Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Hongjing Qu"'
Autor:
Frank Nestle, Ilana Mandel, Dana Haves Ziv, Ilana Goldshtein, Tsuri Peretz, Dror Alishekevitz, Anna Fridman Dror, Motti Hakim, Sharon Hashmueli, Itay Friedman, Yair Sapir, Rita Greco, Hongjing Qu, Dmitri Wiederschain, Lily Pao, Sharad Sharma, Tehila Ben Moshe
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Background Cancer immunotherapy has revolutionized cancer treatment. However, considering the limited success of immunotherapy to only some cancer types and patient cohorts, there is an unmet need for developing new treatments that will result in hig
Externí odkaz:
https://doaj.org/article/ff4c9ecab5914d4a9dd2936b42567401
Autor:
Rita Greco, Hongjing Qu, Hui Qu, Joachim Theilhaber, Gary Shapiro, Richard Gregory, Christopher Winter, Natalia Malkova, Frank Sun, Julie Jaworski, Annie Best, Lily Pao, Andrew Hebert, Mikhail Levit, Alexei Protopopov, Jack Pollard, Keith Bahjat, Dmitri Wiederschain, Sharad Sharma
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
TGFβ is a pleiotropic cytokine that may have both tumor inhibiting and tumor promoting properties, depending on tissue and cellular context. Emerging data support a role for TGFβ in suppression of antitumor immunity. Here we show that SAR439459, a
Externí odkaz:
https://doaj.org/article/038bbe26fd6d49499faa4d6f245b51f2
Autor:
Jian Zhu, Teresa Davoli, Jill M. Perriera, Christopher R. Chin, Gaurav D. Gaiha, Sinu P. John, Frederic D. Sigiollot, Geng Gao, Qikai Xu, Hongjing Qu, Thomas Pertel, Jennifer S. Sims, Jennifer A. Smith, Richard E. Baker, Louise Maranda, Aylwin Ng, Stephen J. Elledge, Abraham L. Brass
Publikováno v:
Cell Reports, Vol 9, Iss 2, Pp 752-766 (2014)
RNAi screens have implicated hundreds of host proteins as HIV-1 dependency factors (HDFs). While informative, these early studies overlap poorly due to false positives and false negatives. To ameliorate these issues, we combined information from the
Externí odkaz:
https://doaj.org/article/b80c3f7209634aecb2d5e9756a0d87f6
Autor:
Jian Zhu, Gaurav D. Gaiha, Sinu P. John, Thomas Pertel, Christopher R. Chin, Geng Gao, Hongjing Qu, Bruce D. Walker, Stephen J. Elledge, Abraham L. Brass
Publikováno v:
Cell Reports, Vol 2, Iss 4, Pp 807-816 (2012)
HIV-1 depends on many host factors for propagation. Other host factors, however, antagonize HIV-1 and may have profound effects on viral activation. Curing HIV-1 requires the reduction of latent viral reservoirs that remain in the face of antiretrovi
Externí odkaz:
https://doaj.org/article/c79ff68d377844489f7b58a07affe3be
Autor:
Hubert Lam, Xingyue He, Cheryl Black, Michele Hoffmann, Joshua Francis, James Parsons, Christian Roy, Jinsheng Liang, Hongjing Qu, Martin Campbell, Tomasz Sewastianik, Jessica Webb, Aude Chapuis, Thomas Schmitt, Philip Greenberg, Damien Hallet, Markus Vallaster, Piotr Pierog, Gary Shapiro, Loic Vincent
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Xingyue He, Michelle Hoffmann, Jinsheng Liang, Hongjing Qu, Allison Drain, Hubert Lam, Shannon Oda, Thomas Schmitt, Aude Chapuis, Philip Greenberg, Gary Shapiro, Loic Vincent
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Qikai Xu, Louise Maranda, Teresa Davoli, Sinu P. John, Thomas Pertel, Christopher R. Chin, Hongjing Qu, Richard Baker, Jian Zhu, Jennifer A. Smith, Abraham L. Brass, Geng Gao, Jill M. Perriera, Stephen J. Elledge, Frederic D. Sigiollot, Aylwin Ng, Gaurav D. Gaiha, Jennifer S. Sims
Publikováno v:
Cell Reports, Vol 9, Iss 2, Pp 752-766 (2014)
Cell reports
Cell reports
SUMMARY RNAi screens have implicated hundreds of host proteins as HIV-1 dependency factors (HDFs). While informative, these early studies overlap poorly due to false positives and false negatives. To ameliorate these issues, we combined information f
Autor:
Peter J. Park, Lovelace J. Luquette, Yifang Liu, Hongjing Qu, Ruibin Xi, Stephen J. Elledge, Long Hu, Zhi John Lu, Geng Gao, Xu Tan
Publikováno v:
Nature biotechnology
The systematic identification of effective drug combinations has been hindered by the unavailability of methods that can explore the large combinatorial search space of drug interactions. Here we present a multiplex screening method named MuSIC (Mult
Autor:
Qikai Xu, Hongjing Qu, Scott W. Lowe, Xu Tan, Stephen J. Elledge, Christof Fellmann, Mamie Z. Li, Zhi John Lu, Long Hu, Geng Gao, Gregory J. Hannon
Publikováno v:
Proceedings of the National Academy of Sciences. 109:869-874
shRNAs can trigger effective silencing of gene expression in mammalian cells, thereby providing powerful tools for genetic studies, as well as potential therapeutic strategies. Specific shRNAs can interfere with the replication of pathogenic viruses
Autor:
Tun Tun Lin, Waldemar Racki, Rita Greco, Fangxian Sun, Dmitri Wiederschain, Jack Pollard, Natalia Malkova, Christopher Winter, Mikhail Levit, Gary Shapiro, Keli Perron, Hongjing Qu, Richard Gregory
Publikováno v:
Cancer Research. 78:2790-2790
TGFβ may act as a tumor suppressor early in tumorigenesis; however, TGFβ is also known to support tumor growth via multiple mechanisms, including promotion of epithelial-mesenchymal transition, fibroblast recruitment, ECM deposition, neovasculariza