Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Hongjiao Xiang"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Objective: Changes in bile acids (BAs) are increasingly recognized as potential targets for non-alcoholic steatohepatitis (NASH). Kaempferol has been proved to be anti-inflammatory and reduce the disorder of lipid metabolism. In order to analyze the
Externí odkaz:
https://doaj.org/article/386944a2fcc24ae0822ea1bbaac5257d
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease around the world, and it often coexists with insulin resistance-related diseases including obesity, diabetes, hyperlipidemia, and hypertension, which seriously threate
Externí odkaz:
https://doaj.org/article/df25e9f3dc8f485fa004c26dcbf9ccc8
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 148, Iss , Pp 112771- (2022)
As a new type of natural flavonoids, dihydromyricetin (DMY) has attracted more and more attention. It has a series of pharmacological effects, such as anti-inflammatory, anti-tumor, anti-oxidation, antibacterial and so on, and it is almost no toxicit
Externí odkaz:
https://doaj.org/article/53ab00fc84f44e0b91e22112916db5fe
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 147, Iss , Pp 112677- (2022)
Lecithin: cholesterol acyltransferase (LCAT) is the only enzyme in plasma which is able to esterify cholesterol and boost cholesterol esterify with phospholipid-derived acyl chains. In order to better understand the progress of LCAT research, it is a
Externí odkaz:
https://doaj.org/article/e24e26b6bc4b48e4becc7b18eb5aaad0
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Endoplasmic reticulum stress (ERS) plays a key role in alcohol liver injury (ALI). Lysophosphatidylcholine acyltransferase 3 (LPCAT3) is a potential modifier of ERS. It was examined whether the protective effect of Qinggan Huoxue Recipe (QGHXR) again
Externí odkaz:
https://doaj.org/article/0bcbcbdcff2e40a2832a129a59640f4e
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 141, Iss , Pp 111918- (2021)
Diabetic kidney disease (DKD) is not only one of the main complications of diabetes, but also the leading cause of the end-stage renal disease (ESRD). The occurrence and development of DKD have always been a serious clinical problem that leads to the
Externí odkaz:
https://doaj.org/article/ba339aff110a4d43b82a0253820cefca
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 139, Iss , Pp 111610- (2021)
Sphingomyelin (SM) can be converted into ceramide (Cer) by neutral sphingomyelinase (NSM) and acid sphingomyelinase (ASM). Cer is a second messenger of lipids and can regulate cell growth and apoptosis. Increasing evidence shows that NSM and ASM play
Externí odkaz:
https://doaj.org/article/d811250fe0174125989deac1d428d43b
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Kaempferol (KP) has a variety of biological effects such as anti-inflammatory, anti-oxidant, anti-aging and cardiovascular protection. Whether KP has a therapeutic effect on non-alcoholic steatohepatitis (NASH), and the detailed mechanism
Externí odkaz:
https://doaj.org/article/d372c64e02fa49df89e44f2f03cee3a4
Autor:
Junmin Wang, Yifei Lu, Caiyun Zhang, Shuxia Tian, Hongjiao Xiang, Peilun Ding, Junming Chen, Guang Ji, Tao Wu
Publikováno v:
International Journal of Medical Sciences. 20:346-358
Publikováno v:
Journal of Cancer
The human patatin-like phospholipase domain-containing 3 gene (PNPLA3) is highly expressed in liver and adipose tissue and encodes a transmembrane polypeptide chain containing 481 amino acids. The I148M variant of PNPLA3 is a single nucleotide polymo