Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Honghui Mao"'
Autor:
Junye Ge, Pengfei Ren, Biqing Tian, Jiaqi Li, Chuchu Qi, Qiyi Huang, Keke Ren, Erling Hu, Honghui Mao, Ying Zang, Shengxi Wu, Qian Xue, Wenting Wang
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110165- (2024)
Summary: Self-grooming is an innate stereotyped behavior influenced by sense and emotion. It is considered an important characteristic in various disease models. However, the neural circuit mechanism underlying sensory-induced and emotion-driven self
Externí odkaz:
https://doaj.org/article/ee2dd881bb634082b33355cbaa0ff65d
Axin2 coupled excessive Wnt‐glycolysis signaling mediates social defect in autism spectrum disorders
Autor:
Mengmeng Wang, Panpan Xian, Weian Zheng, Zhenzhen Li, Andi Chen, Haoxiang Xiao, Chao Xu, Fei Wang, Honghui Mao, Han Meng, Youyi Zhao, Ceng Luo, Yazhou Wang, Shengxi Wu
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 6, Pp 1-20 (2023)
Abstract Social dysfunction is the core syndrome of autism spectrum disorder (ASD) and lacks effective medicine. Although numerous risk genes and relevant environmental factors have been identified, the convergent molecular mechanism underlying ASD
Externí odkaz:
https://doaj.org/article/e52c2912ea124d4eb4fccce223ad9ddb
Autor:
Hong Fan, Jialei Yang, Kun Zhang, Junling Xing, Baolin Guo, Honghui Mao, Wenting Wang, Yingzhou Hu, Wei Lin, Ying Huang, Jian Ding, Caiyong Yu, Fanfan Fu, Li Sun, Jing Wu, Youyi Zhao, Wenbin Deng, Chengji Zhou, Mengsheng Qiu, Shengxi Wu, Yu-Qiang Ding, Yazhou Wang
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-17 (2022)
Abstract Reactive astrogliosis usually bears some properties of neural progenitors. How injury triggers astrocyte dedifferentiation remains largely unclear. Here, we report that ischemia induces rapid up-regulation of Wnt2 protein in apoptotic neuron
Externí odkaz:
https://doaj.org/article/5551ee1e4cd24382b142c66bf6f4be8a
Autor:
Ming Zhang, Jian Wang, Kaixiang Zhang, Guozhen Lu, Yuming Liu, Keke Ren, Wenting Wang, Dazhuan Xin, Lingli Xu, Honghui Mao, Junlin Xing, Xingchun Gao, Weilin Jin, Kalen Berry, Katsuhiko Mikoshiba, Shengxi Wu, Q. Richard Lu, Xianghui Zhao
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
Myelin formation is regulated by epigenetic mechanisms and ensures proper neuronal function during development and after demyelination. Here, the authors show that TET1, a DNA hydroxymethylase, regulates myelination during development and remyelinati
Externí odkaz:
https://doaj.org/article/e1cbd11d253c49be9a1549ae252b0873
Autor:
Chuchu Qi, Andi Chen, Honghui Mao, Erling Hu, Junye Ge, Guaiguai Ma, Keke Ren, Qian Xue, Wenting Wang, Shengxi Wu
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Environmental factors, such as medication during pregnancy, are one of the major causes of autism spectrum disorder (ASD). Valproic acid (VPA) intake during pregnancy has been reported to dramatically elevate autism risk in offspring. Recently, resea
Externí odkaz:
https://doaj.org/article/fd0ebc128a8a498fa236606b58a8f4b4
Autor:
Kaiwen Xi, Xin Huang, Tiaotiao Liu, Yang Liu, Honghui Mao, Mengmeng Wang, Dayun Feng, Wenting Wang, Baolin Guo, Shengxi Wu
Publikováno v:
Neurobiology of Stress, Vol 15, Iss , Pp 100391- (2021)
Post-traumatic stress disorder (PTSD) is a severe, long-term psychological disorder triggered by distressing events. The neural basis and underlying mechanisms of PTSD are not completely understood. Therefore, it is important to determine the patholo
Externí odkaz:
https://doaj.org/article/39f3baf1fc66446dafd971183a69a38c
Autor:
Haiying Liu, Xin Huang, Jinwei Xu, Honghui Mao, Yaohao Li, Keke Ren, Guaiguai Ma, Qian Xue, Huiren Tao, Shengxi Wu, Wenting Wang
Publikováno v:
Neurobiology of Stress, Vol 15, Iss , Pp 100417- (2021)
Self-grooming is an innate, cephalo-caudal progression of body cleaning behaviors that are found in normal rodents but exhibit repetitive and stereotyped patterns in several mouse models, such as autism spectrum disorders (ASDs). It is also recognize
Externí odkaz:
https://doaj.org/article/afbcc5e69918403ea7dcae54442cf8c3
Autor:
Di Chen, Keke Ren, Haiying Liu, Honghui Mao, Zongyan Li, Huiming Mo, Shengjun Xie, Yiwu Shi, Qian Chen, Wenting Wang
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Single neurons, as the basic unit of the brain, consist of a cell body and processes, including dendrites and axons. Even neurons of the same type show various subtle process characteristics to fit into the diverse neural circuits. Different cell typ
Externí odkaz:
https://doaj.org/article/982808b0cdc346418c5053ad288dd589
Autor:
Haiying Liu, Xin Huang, Yaohao Li, Kaiwen Xi, Yiting Han, Honghui Mao, Keke Ren, Wenting Wang, Zhongliang Wu
Publikováno v:
Brain, Behavior, and Immunity. 100:254-266
Acute sleep deprivation is a common condition in modern life and increases anxiety symptoms in healthy individuals. The neuroinflammatory response induced by microglial activation could be an important contributing factor, but its underlying molecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68cc0630aa529a2856bb7e4f529ebc74
https://doi.org/10.1016/j.bbi.2021.12.006
https://doi.org/10.1016/j.bbi.2021.12.006
Autor:
Kaiwen Xi, Haoxiang Xiao, Xin Huang, Ziduo Yuan, Mingyue Liu, Honghui Mao, Haiying Liu, Guaiguai Ma, Zishuo Cheng, Yuqiao Xie, Yang Liu, Dayun Feng, Wenting Wang, Baolin Guo, Shengxi Wu
Publikováno v:
Science Advances. 9
Posttraumatic stress disorder (PTSD) is a highly prevalent and debilitating psychiatric disease often accompanied by severe defensive behaviors, preventing individuals from integrating into society. However, the neural mechanisms of defensiveness in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::968233d401ea9f0578d5777e479c2d17
https://doi.org/10.1126/sciadv.ade5987
https://doi.org/10.1126/sciadv.ade5987