Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Honghui Ma"'
Autor:
Xiwen Xiong, Chenyan Yang, Wei-Qi He, Jiahui Yu, Yue Xin, Xinge Zhang, Rong Huang, Honghui Ma, Shaofang Xu, Zun Li, Jie Ma, Lin Xu, Qunyi Wang, Kaiqun Ren, Xiaoli S. Wu, Christopher R. Vakoc, Jiateng Zhong, Genshen Zhong, Xiaofei Zhu, Yu Song, Hai-Bin Ruan, Qingzhi Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Host defense against helminth infection is mediated by mucosal type 2 immunity. Using gain- and loss-of-function mouse models, and mouse intestinal organoids, Xiong et al. show that SIRT6 modulates tuft and goblet cell expansion in intestinal epithel
Externí odkaz:
https://doaj.org/article/b85f1eb3871d4e778a95e572a2222fdd
Autor:
Jian Huang, Luxin Wang, Yunli Shen, Shengqi Zhang, Yaqun Zhou, Jimin Du, Xiue Ma, Yi Liu, Dandan Liang, Dan Shi, Honghui Ma, Li Li, Qi Zhang, Yi-Han Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Phosphorylation catalyzed by kinases is a key event in signaling pathways involved in cardiomyocyte hypertrophy. Here the authors show that the kinase CLK4 ameliorates cardiac hypertrophy by phosphorylating NEXN.
Externí odkaz:
https://doaj.org/article/36d9e20912b44883a99753a01abd9262
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Several functions have been proposed for m6A in RNA metabolism, yet little is known regarding the specific functions of individual m6A readers. Here, the authors observe that the m6A reader YTHDC2 — which contains an RNA helicase domain — acts on
Externí odkaz:
https://doaj.org/article/3ca83b1462a8473fb1ee44b8fa43183d
Publikováno v:
Protein & Cell, Vol 11, Iss 4, Pp 304-307 (2019)
Externí odkaz:
https://doaj.org/article/1f3b3814cf1b43bf8ec0f00152e258e2
Publikováno v:
Shock and Vibration, Vol 2017 (2017)
Failure of cutterhead driving system (CDS) of tunnel boring machine (TBM) often occurs under shock and vibration conditions. To investigate the dynamic characteristics and reduce system vibration further, an electromechanical coupling model of CDS is
Externí odkaz:
https://doaj.org/article/91ab14eae0c34655abb0a93835bf7dae
Autor:
Liudan Jiang, Jiayong Yin, Maoxiang Qian, Shaoqin Rong, Shengqi Zhang, Kejing Chen, Chengchen Zhao, Yuanqing Tan, Jiayin Guo, Hao Chen, Siyun Gao, Tingting Liu, Yi Liu, Bin Shen, Jian Yang, Yong Zhang, Fei-Long Meng, Jinchuan Hu, Honghui Ma, Yi-Han Chen
Publikováno v:
Journal of the American Chemical Society. 144:1323-1331
As an aberrant base in DNA, uracil is generated by either deoxyuridine (dU) misincorporation or cytosine deamination, and involved in multiple physiological and pathological processes. Genome-wide profiles of uracil are important for study of these p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba32025634db6f27a047903241207d6f
https://doi.org/10.1021/jacs.1c11269
https://doi.org/10.1021/jacs.1c11269
Autor:
Honghui Ma, Chenyan Yang, Jing Wang, Qingzhi Wang, Jie Ma, Zun Li, Xiwen Xiong, Rong Huang, Lin Xu
Publikováno v:
Biochemical and Biophysical Research Communications. 578:142-149
The mechanistic target of rapamycin complex 1 (mTORC1) acts as a central regulator of metabolic pathways that drive cellular growth. Abnormal activation of mTORC1 occurs at high frequency in human and mouse hepatocellular carcinoma (HCC). DEP domain-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::def04e2b35a89df5aff2693f70003df7
https://doi.org/10.1016/j.bbrc.2021.09.036
https://doi.org/10.1016/j.bbrc.2021.09.036
Autor:
Yanjiao Ruan, Honghui Ma, Shengqi Zhang, Hongyu Chen, Dan Shi, Bin Shen, Lei Chen, Haifeng Sun, Yi-Han Chen, Yi Liu, Kejing Chen, Xueying Gu, Hao Chen, Liang Xu, Dandan Liang, Liudan Jiang, Siyun Gao, Jian Yang
Publikováno v:
Journal of Cellular and Molecular Medicine
N 6‐methyladenosine (m6A) is the most prevalent modification in mRNA and engages in multiple biological processes. Previous studies indicated that m6A methyltransferase METTL3 (‘writer’) and demethylase FTO (‘eraser’) play critical roles in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccf523598402d0334a874fc7e248b6af
http://europepmc.org/articles/PMC8642692
http://europepmc.org/articles/PMC8642692
Autor:
Qingzhi Wang, Chenyan Yang, Mingyong Wang, Rong Huang, Zun Li, Xiwen Xiong, Jinghong Zhang, Bo Sun, Honghui Ma, Jie Ma, Yiping Shi
Publikováno v:
Biochemical and Biophysical Research Communications. 569:118-124
The mammalian target of rapamycin complex 1 (mTORC1) is a crucial regulator of adipogenesis and systemic energy metabolism. Its dysregulation leads to a diversity of metabolic diseases, including obesity and type 2 diabetes. DEP-domain containing 5 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87bcd6ca225ca2b18f7315781aacd169
https://doi.org/10.1016/j.bbrc.2021.07.003
https://doi.org/10.1016/j.bbrc.2021.07.003
Publikováno v:
Journal of the American Chemical Society. 143:10902-10909
The asymmetric hydroboration of alkenes has proven to be among the most powerful methods for the synthesis of chiral boron compounds. This protocol is well suitable for activated alkenes such as vinylarenes and alkenes bearing directing groups. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f13ca2ced18af15de3bb43607c4129
https://doi.org/10.1021/jacs.1c06697
https://doi.org/10.1021/jacs.1c06697