Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Hongguang Nie"'
Submersion and hypoxia inhibit alveolar epithelial Na+ transport through ERK/NF-κB signaling pathway
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background Hypoxia is associated with many respiratory diseases, partly due to the accumulation of edema fluid and mucus on the surface of alveolar epithelial cell (AEC), which forms oxygen delivery barriers and is responsible for the disrup
Externí odkaz:
https://doaj.org/article/2170e0acc0834f8ebdc5272bdf2c4212
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 169, Iss , Pp 115896- (2023)
Acute lung injury (ALI) is a progressive inflammatory injury, and mesenchymal stem cells (MSCs) can be used to treat ALI. MSC-conditioned medium (MSC-CM) contains many cytokines, in which keratinocyte growth factor (KGF) is a soluble factor that play
Externí odkaz:
https://doaj.org/article/88bb4f032ce64e47a8bab9c90eab7099
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 163, Iss , Pp 114863- (2023)
Lifeways of worldwide people have changed dramatically amid the coronavirus disease 2019 (COVID-19) pandemic, and public health is at stake currently. In the early stage of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, fibri
Externí odkaz:
https://doaj.org/article/24a9377e248448e4a00c01b81d807da4
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-7 (2022)
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) represents a pandemic threat that has been declared a public health emergency of international concern, whereas the effects of cellula
Externí odkaz:
https://doaj.org/article/c54700a74803495abf9d1371d850f36a
Ferulic acid ameliorates lipopolysaccharide-induced tracheal injury via cGMP/PKGII signaling pathway
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background Tracheal injury is a common clinical condition that still lacks an effective therapy at present. Stimulation of epithelial sodium channel (ENaC) increases Na+ transport, which is a driving force to keep tracheal mucosa free edema
Externí odkaz:
https://doaj.org/article/ede9583247eb480c88fbe2a61eb3e962
Autor:
Jianjun Chang, Hongguang Nie, Xin Ge, Jie Du, Weicheng Liu, Xue Li, Yue Sun, Xinzhi Wei, Zhe Xun, Yan Chun Li
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Idiopathic pulmonary fibrosis (IPF) is a severe disorder leading to progressive and irreversible loss of pulmonary function. In this study we investigated the anti-fibrotic effect of vitamin D using a mouse model of IPF. Lung fibrosis was in
Externí odkaz:
https://doaj.org/article/6b82009ba29f42d6a720d696b13be5a8
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10122 (2023)
Luteolin (Lut), a natural flavonoid compound existing in Perilla frutescens (L.) Britton, has been proven to play a protective role in the following biological aspects: inflammatory, viral, oxidant, and tumor-related. Lut can alleviate acute lung inj
Externí odkaz:
https://doaj.org/article/3752bd733bc7403b8d3879a2e98e506e
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8011 (2023)
Ferulic acid (FA), a prevalent dietary phytochemical, has many pharmacological effects, including anti-oxidation and anti-inflammation effects, and has been widely used in the pharmaceutical, food, and cosmetics industries. Many studies have shown th
Externí odkaz:
https://doaj.org/article/705fe6e7b7ea4b1eb85427f02f6962db
Publikováno v:
Biomolecules, Vol 13, Iss 4, p 578 (2023)
Dyspnea and progressive hypoxemia are the main clinical features of patients with coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Pulmonary pathology shows diffuse alveolar damage
Externí odkaz:
https://doaj.org/article/cb58abc440ac4fb09c53bb852aa4666a
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-14 (2020)
Abstract Aims Acute lung injury (ALI) is a clinical syndrome with high morbidity and mortality, and severe pulmonary edema is one of the characteristics. Epithelial sodium channel (ENaC) located on the apical side of alveolar type 2 epithelial (AT2)
Externí odkaz:
https://doaj.org/article/42cd8f7b6f8747babe3bb36b87766ba0