Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Hongge Fa"'
Autor:
Hongge Fa, Dandan Xiao, Wenguang Chang, Lin Ding, Lanting Yang, Yu Wang, Mengyu Wang, Jianxun Wang
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
ObjectiveMany studies have reported that microRNAs (miRs) are involved in the regulation of doxorubicin (DOX)-induced cardiotoxicity. MiR-194-5p has been reported significantly upregulated in patients with myocardial infarction; however, its role in
Externí odkaz:
https://doaj.org/article/cdd1bc4f4358430da4ef827825b9e414
Publikováno v:
Acta Pharmacol Sin
Anthracyclines, such as doxorubicin (DOX), are well known for their high efficacy in treating multiple cancers, but their clinical usage is limited due to their potential to induce fatal cardiotoxicity. Such detrimental effects significantly impact t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93afba8f7ccedebd318a709cff108fbf
https://europepmc.org/articles/PMC8114921/
https://europepmc.org/articles/PMC8114921/
Publikováno v:
Theranostics
Cancer is a leading cause of mortality and morbidity worldwide. Despite major improvements in current therapeutic methods, ideal therapeutic strategies for improved tumor elimination are still lacking. Recently, immunotherapy has attracted much atten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6749511f79e9b4ad3d3f88b770a32518
https://pubmed.ncbi.nlm.nih.gov/32802188
https://pubmed.ncbi.nlm.nih.gov/32802188
Publikováno v:
Molecular and cellular endocrinology. 508
Cardiovascular complication is a major cause of mortality and morbidity in patients with diabetes. Insulin sensitivity loss is a major contributor to the pathogenesis of cardiovascular diseases in diabetes. Based on our previous research, diacylglyce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e055524f635f61fb6625d94499938f
https://pubmed.ncbi.nlm.nih.gov/32229289
https://pubmed.ncbi.nlm.nih.gov/32229289
Publikováno v:
Toxicology letters. 330
The clinical usage of Doxorubicin (DOX) is limited due to its cardiotoxicity. Although the precise mechanism remains unclear, there is an increasing body of evidence that has demonstrated that mitophagy is responsible for DOX-induced cardiotoxicity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59966fd9c13c1c61ba243aeacb899f90
https://pubmed.ncbi.nlm.nih.gov/32434049
https://pubmed.ncbi.nlm.nih.gov/32434049