Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Hongfei Tong"'
Autor:
Huihui Chen, Yinjuan Ding, Weizhong Zhou, Jiajia Li, Weite Qian, Zhe Zhang, Chao Li, Hongfei Tong, Xing Rong, Maoping Chu, Congde Chen, Dexuan Wang, Xiaoling Guo
Publikováno v:
Stem Cell Research, Vol 51, Iss , Pp 102209- (2021)
The gene mutations of the chloride channel gene (CLCN5) can lead to the inherited X-linked Dent disease (X-Dent). The urine cells of a 4-year-old male X-Dent patient with the hemizygous CLCN5 gene mutation p.R718* (c.2152C > T) were reprogrammed into
Externí odkaz:
https://doaj.org/article/b045a2098a374bd09b16e13315a297bb
Autor:
Yinjuan Ding, Long Wang, Weiping Ji, Zhanguo Chen, Dexuan Wang, Congde Chen, Hongfei Tong, Zhao Han, Chao Niu, Maoping Chu, Jinyu Huang, Xiaoling Guo
Publikováno v:
Stem Cell Research, Vol 49, Iss , Pp 102064- (2020)
Human induced pluripotent stem (iPS) cells expressing Cas9 protein are valuable for the pathogenic mechanism study and drug discovery. These cells can be efficiently induced to differentiate into disease cell models with specific mutations through ad
Externí odkaz:
https://doaj.org/article/7b304af97c644a049bf7b8c54362451f
Autor:
Xiaoling Guo, Weiping Ji, Chao Niu, Yinjuan Ding, Zhanguo Chen, Congde Chen, Hongfei Tong, Zhao Han, Maoping Chu
Publikováno v:
Stem Cell Research, Vol 49, Iss , Pp 102085- (2020)
The gene mutations of the collagen type IV alpha 5 chain (COL4A5) can lead to the inherited haematuria to end-stage renal disease X-linked Alport syndrome (X-LAS). The urine cells of a 5-year-old male X-LAS patient carrying a hemizygous COL4A5 gene m
Externí odkaz:
https://doaj.org/article/d81f04a7266c46f48b656cdeca3370c9
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87603 (2014)
BACKGROUND: Epidemics of HFMD are elevated every year globally, especially in mainland China. The disease now presents as an increasing threat to public health worldwide. METHODS: Five hundred and seventy-one EV71-infected HFMD patients in Beijing Yo
Externí odkaz:
https://doaj.org/article/f19a7bf8e8234e8d83aba65137834688
Autor:
Wei Li, Xiaojie Huang, Hongfei Tong, Yuxuan Wang, Tong Zhang, Wen Wang, Lili Dai, Tongzeng Li, Shengzhang Lin, Hao Wu
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47040 (2012)
BACKGROUND/OBJECTIVE: IFNs are a group of cytokines that possess potent antiviral and antitumor activities, while β-catenin pathway is a proliferative pathway involved in carcinogenesis. Interaction between these two pathways has not been well elabo
Externí odkaz:
https://doaj.org/article/cd50fb238fd045c1a95d4fbc90e51b3e
Publikováno v:
Journal of Molecular Neuroscience. 72:1334-1344
The aim of this study was to analyze the efficacy and underlying mechanism of adipose-derived mesenchymal stem cell exosome (ADSC-exosomes)–mediated protection on methotrexate (MTX)–induced neuronal damage. We established a H2O2induced oxidativ
Publikováno v:
OncoTargets and Therapy. 13:9839-9848
Background Pancreatic cancer is one of the most malignant tumors, and gemcitabine has been considered as the standard treatment and been widely utilized as a first-line drug for advanced pancreatic cancer, but gemcitabine-resistance always occurs aft
Publikováno v:
Cancer Management and Research. 11:8463-8473
Background Excessive expression of EGFR is closely related to tumor formation, transfer and deterioration, which has attracted much attention. EGFR overexpression may be detected in up to 90% of pancreatic tumors. However, drug resistance of EGFR inh
Autor:
Yi Liao, Meimei He, Bin Zhou, Junxue Tu, Hai-Bin Liu, Hongfei Tong, Jingjing Chen, Zhao-Hong Wang
Publikováno v:
OncoTargets and Therapy. 12:5153-5162
Background Hepatocellular carcinoma (HCC) is the second leading cause of death among cancers worldwide. In this study, we aimed to identify the molecular target genes and detect the key mechanisms of HCC. Three gene expression profiles (GSE84006, GSE
Autor:
Congde Chen, Yinjuan Ding, Zhao Han, Chao Niu, Xiaoling Guo, Maoping Chu, Zhanguo Chen, Weiping Ji, Hongfei Tong
Publikováno v:
Stem Cell Research, Vol 49, Iss, Pp 102085-(2020)
The gene mutations of the collagen type IV alpha 5 chain (COL4A5) can lead to the inherited haematuria to end-stage renal disease X-linked Alport syndrome (X-LAS). The urine cells of a 5-year-old male X-LAS patient carrying a hemizygous COL4A5 gene m