Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Hongdong Shi"'
Publikováno v:
Molecules, Vol 26, Iss 15, p 4389 (2021)
Lung cancer is one of the most common malignancies with the highest mortality rate and the second-highest incidence rate after breast cancer, posing a serious threat to human health. The accidental discovery of the antitumor properties of cisplatin i
Externí odkaz:
https://doaj.org/article/a90069ddd8d94cfeb7e90ad9e2f8c953
Publikováno v:
Dalton Transactions. 50:14498-14512
With the highest incidence, breast cancer is the leading cause of cancer deaths among women in the world. Tumor metastasis is the major contributor of high mortality in breast cancer, and the existence of cancer stem cells (CSCs) has been proven to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd4faec00360effcfd647efdaa339a7b
https://doi.org/10.1039/d1dt02909f
https://doi.org/10.1039/d1dt02909f
Publikováno v:
Dalton transactions (Cambridge, England : 2003). 51(17)
Ruthenium polypyridyl complexes have been widely used as bioprobes and photosensitizers. However, several disadvantages including slow cellular uptake, nonspecific binding with biomolecules and toxicity limit their applications. In this study, a nano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea12a8533d7404743cc19b83a9c704ff
https://pubmed.ncbi.nlm.nih.gov/35438705
https://pubmed.ncbi.nlm.nih.gov/35438705
Autor:
Qianling Zhang, Hongdong Shi, Jin-Gang Liu, Zigang Li, Yi Wang, Xiaoyan Chai, Pingyu Zhang, Haijie Chen, Weirong Qin
Publikováno v:
Dalton Transactions. 49:972-976
An HCBP1 peptide-ruthenium conjugate (Ru-β-Ala-FQHPSFI) as a potential candidate for targeted therapy of hepatoma was synthesized. Ru-β-Ala-FQHPSFI shows drastically enhanced cytotoxicity and high selectivity for hepatoma cells versus noncancer liv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b42f84e923a34d71513fa91b641daa88
https://doi.org/10.1039/c9dt03856f
https://doi.org/10.1039/c9dt03856f
Autor:
Yucai Wang, Kai Zhong, Hai Huang, Yangzhong Liu, Tiantian Wu, Yun Wu, Hongdong Shi, Hongyi Yang
Publikováno v:
Chemical Communications. 55:5175-5178
A multifunctional nanobody-drug conjugate (NDC) was constructed in this work for the targeted delivery of a platinum prodrug and an MRI contrast agent. The NDC can be specifically internalized into EGFR positive cancer cells, resulting in higher ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a419c5684d7113d9cb1db554c9702e42
https://doi.org/10.1039/c9cc01391a
https://doi.org/10.1039/c9cc01391a
Publikováno v:
Dalton transactions (Cambridge, England : 2003). 50(19)
Iridium complexes have been widely applied as molecular sensors because of their rich photophysical properties, including large Stokes shifts, long emission lifetimes, environment-sensitive emissions, and high luminescence quantum yields. In this pap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24054758bb60eeeca513554585c8def7
https://pubmed.ncbi.nlm.nih.gov/33900334
https://pubmed.ncbi.nlm.nih.gov/33900334
Publikováno v:
Journal of materials chemistry. B. 3(47)
Intracellular protein delivery has great biomedical applications; the safe and efficient delivery vectors are crucial for achieving this goal. Here we report a platform for efficient protein delivery using calcium phosphate (CaP) nanoparticles. The w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f085d9e524435c5c3624b8a7084dfb
https://pubmed.ncbi.nlm.nih.gov/32263125
https://pubmed.ncbi.nlm.nih.gov/32263125
Publikováno v:
Journal of materials chemistry. B. 6(7)
Targeted delivery of anticancer drugs that selectively accumulate in malignant cells could enhance drug efficacy and reduce side effects of conventional chemotherapy. In this work, we designed a single domain antibody (nanobody) based drug delivery s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa400b57440a6188963c1ed0405358b
https://pubmed.ncbi.nlm.nih.gov/32254288
https://pubmed.ncbi.nlm.nih.gov/32254288
Autor:
Hongdong Shi, Jingxue Lou, Yi Wang, Simin Lin, Yangzhong Liu, Pingyu Zhang, Qianling Zhang, Hu Yatao
Publikováno v:
Journal of Inorganic Biochemistry. 221:111489
Inspired by the unique glass cell wall of diatom, we design a new nanostructure of human serum albumin nanoparticle (HSANP) coated with silica (HSA/SiO2), which consists of a core-satellite assembly of small silica nanoparticles on a single HSANP. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b2475968adcf97f10fa963176e45da9
https://doi.org/10.1016/j.jinorgbio.2021.111489
https://doi.org/10.1016/j.jinorgbio.2021.111489
Autor:
Hai Huang, Jun Wang, Yucai Wang, Yangzhong Liu, Yuanzeng Min, Hongdong Shi, Jing Liu, Andrew Z. Wang
Publikováno v:
Chemical Communications. 53:212-215
Co-delivery of all-trans-retinoic acid and paclitaxel using albumin-bound nanoparticles demonstrated a significantly improved anti-metastatic effect to breast cancer both in vitro and in vivo. Notably, the co-delivery nanoparticles exhibited more pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f21a529e9fe0a827953569885d9727b7
https://doi.org/10.1039/c6cc08146k
https://doi.org/10.1039/c6cc08146k