Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Hongdi Meng"'
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106485 (2014)
Although chemotherapy-induced peripheral neuropathy (CIPN) is a dose-limiting side effect of platinum drugs, the mechanisms of this toxicity remain unknown. Previous work in our laboratory suggests that cisplatin-induced CIPN is secondary to DNA dama
Externí odkaz:
https://doaj.org/article/40cd0620932046fbb7a88a310540a022
Publikováno v:
Molecular and Cellular Neuroscience. 82:105-117
Peripheral neuropathy is a dose-limiting and debilitating side effect of the chemotherapeutic drug, paclitaxel. Consequently, elucidating the mechanisms by which this drug alters sensory neuronal function is essential for the development of successfu
Publikováno v:
Brain and Development. 34:739-745
Clinical findings, pathological features and tripeptidyl peptidase 1 (TPP1) activity and genetic mutation analysis data of nine patients affected with the late-infantile form of neuronal ceroid lipofuscinoses (LINCL) in China are systematically revie
Publikováno v:
Neuropharmacology. 53:81-91
Activity-dependent regulation of BDNF expression plays important roles in synaptic plasticity and neuronal function. We have investigated glutamate receptor-mediated regulation of BDNF expression in the cerebellum of wild-type and stargazer (stg) mic
Publikováno v:
Journal of Neuroscience Methods. 128:1-8
Electrostatic layer-by-layer (LbL) self-assembly, a novel method for ultrathin film coating has been applied to silicone rubber to encourage nerve cell adhesion. The surfaces studied consisted of precursor layers, with alternating cationic poly(ethyl
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106485 (2014)
PLoS ONE
PLoS ONE
Although chemotherapy-induced peripheral neuropathy (CIPN) is a dose-limiting side effect of platinum drugs, the mechanisms of this toxicity remain unknown. Previous work in our laboratory suggests that cisplatin-induced CIPN is secondary to DNA dama
Publikováno v:
Brain research. 1160
The stargazer (stg) mouse exhibits severe cerebellar ataxia, abnormal motor behavior, and absence epilepsy. Selective failure of cerebellar brain-derived neurotrophic factor (BDNF) expression is one of the molecular defects in stg mutant. To determin
Publikováno v:
Brain research. 1124(1)
Stargazin mutation results in absence epilepsy and cerebellar ataxia in stargazer (stg) mice. We have previously discovered defects of AMPA receptor function, failure of BDNF expression and immature morphology specifically in the cerebellar cortex of
Autor:
Xiaoxi Qiao, Hongdi Meng
Publikováno v:
Journal of bioenergetics and biomembranes. 35(6)
Voltage-dependent calcium channels (VDCC) are essential regulators of intracellular calcium concentration, which in turn influences a broad spectrum of cellular functions especially in neurons. Identification of several calcium channel mutations as t
Publikováno v:
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. 19(4)
To investigate mutations of MECP2 gene in classical sporadic Rett syndrome (RTT) patients in China.Polymerase chain reaction, single strand conformation polymorphism, cloning and direct sequencing were employed to analyse the three exons of MECP2 gen