Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Hongde Li"'
Autor:
Weiya Li, Hongde Li, Shiqin Peng, Junli Li, Yuan Feng, Yong Peng, Jiafu Wei, Zhengang Zhao, Tianyuan Xiong, Haoran Yang, Chengxiang Song, Lin Bai, Yijun Yao, Fei Chen, Yue Yin, Mao Chen
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-10 (2024)
Abstract Background The triglyceride glucose (TyG) index, as a reliable marker of insulin resistance, is associated with the incidence and poor prognosis of various cardiovascular diseases. However, the relationship between the TyG index and clinical
Externí odkaz:
https://doaj.org/article/f01ca073a55b4cf194c35904380d113b
Autor:
Nader H. Mahmoudzadeh, Yasaman Heidarian, Jason P. Tourigny, Alexander J. Fitt, Katherine Beebe, Hongde Li, Arthur Luhur, Kasun Buddika, Liam Mungcal, Anirban Kundu, Robert A. Policastro, Garrett J. Brinkley, Gabriel E. Zentner, Travis Nemkov, Robert Pepin, Geetanjali Chawla, Sunil Sudarshan, Aylin R. Rodan, Angelo D'Alessandro, Jason M. Tennessen
Publikováno v:
Molecular Metabolism, Vol 89, Iss , Pp 102013- (2024)
Objectives: The mitochondrial enzyme L-2-hydroxyglutarate dehydrogenase (L2HGDH) regulates the abundance of L-2-hydroxyglutarate (L-2HG), a potent signaling metabolite capable of influencing chromatin architecture, mitochondrial metabolism, and cell
Externí odkaz:
https://doaj.org/article/c959551a1a6c44d4a4238d794febab0c
Landslide susceptibility analysis based on a PSO-DBN prediction model in an earthquake-stricken area
Publikováno v:
Frontiers in Environmental Science, Vol 10 (2022)
In recent years, the major geological hazard of landslides has greatly impact normal human life. Deep belief networks (DBN) is a commonly used deep learning model, and the DBN hyperparameter determination problem is the key to its application. To imp
Externí odkaz:
https://doaj.org/article/6f9b471eddc744cdbf2505c3f9d287b1
Autor:
Hongde Li, Pengfei Rong, Xiaoqian Ma, Wei Nie, Yan Chen, Juan Zhang, Qiong Dong, Min Yang, Wei Wang
Publikováno v:
Journal of Diabetes Research, Vol 2020 (2020)
Transplantation of umbilical cord mesenchymal stem cells (UC-MSCs) is currently considered a novel therapeutic strategy for diabetic nephropathy (DN). However, the mechanisms by which UC-MSCs ameliorate renal fibrosis in DN are not well understood. H
Externí odkaz:
https://doaj.org/article/d8a5d298742846dea5265f93f1c248ba
Publikováno v:
Cancer & Metabolism, Vol 6, Iss 1, Pp 1-11 (2018)
Abstract Background Inflammation, metabolism, and epigenetic modulation are highly interconnected processes that can be altered during tumorigenesis. However, because of the complexity of these interactions, direct cause and effect during tumorigenes
Externí odkaz:
https://doaj.org/article/3e2fffe2c9cf47de91cd35fa96c04cd8
Autor:
Wenlin Zhang, Hongde Li, Diego G. Ogando, Shimin Li, Matthew Feng, Francis W. Price, Jr, Jason M. Tennessen, Joseph A. Bonanno
Publikováno v:
EBioMedicine, Vol 16, Iss C, Pp 292-301 (2017)
Corneal endothelium (CE) is among the most metabolically active tissues in the body. This elevated metabolic rate helps the CE maintain corneal transparency by its ion and fluid transport properties, which when disrupted, leads to visual impairment.
Externí odkaz:
https://doaj.org/article/05d493b6c4604c87a19d3ac27673e71e
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 9 (2018)
The enantiomers of 2-hydroxyglutarate (2HG) are potent regulators of metabolism, chromatin modifications and cell fate decisions. Although these compounds are associated with tumor metabolism and commonly referred to as oncometabolites, both D- and L
Externí odkaz:
https://doaj.org/article/e2b9583676ad4a29863d51b89810fd39
Autor:
Chenhong Zhang, Aihua Yin, Hongde Li, Ruirui Wang, Guojun Wu, Jian Shen, Menghui Zhang, Linghua Wang, Yaping Hou, Haimei Ouyang, Yan Zhang, Yinan Zheng, Jicheng Wang, Xiaofei Lv, Yulan Wang, Feng Zhang, Benhua Zeng, Wenxia Li, Feiyan Yan, Yufeng Zhao, Xiaoyan Pang, Xiaojun Zhang, Huaqing Fu, Feng Chen, Naisi Zhao, Bruce R. Hamaker, Laura C. Bridgewater, David Weinkove, Karine Clement, Joel Dore, Elaine Holmes, Huasheng Xiao, Guoping Zhao, Shengli Yang, Peer Bork, Jeremy K. Nicholson, Hong Wei, Huiru Tang, Xiaozhuang Zhang, Liping Zhao
Publikováno v:
EBioMedicine, Vol 2, Iss 8, Pp 968-984 (2015)
Gut microbiota has been implicated as a pivotal contributing factor in diet-related obesity; however, its role in development of disease phenotypes in human genetic obesity such as Prader–Willi syndrome (PWS) remains elusive. In this hospitalized i
Externí odkaz:
https://doaj.org/article/5ec5bb4f691e4712aeebac59885ecc16
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 2, Pp 2355-2369 (2013)
Cells are constantly damaged by factors that can induce DNA damage. Eukaryotic cells must rapidly load DNA repair proteins onto damaged chromatin during the DNA damage response (DDR). Chromatin-remodeling complexes use the energy from ATP hydrolysis
Externí odkaz:
https://doaj.org/article/ca1852c4f5c0475a8c672dbc826b81c3
Publikováno v:
Journal of Agricultural and Food Chemistry. 71:1405-1416