Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Hongchuan Liu"'
Autor:
Jiawei Guan, Hongchuan Liu, Yan Chai, Jie Yu, Jian Yao, Jing Wang, Zhiwei Pan, Jing Zhang, Yuehua Zhou, Hui Liu, Sheng Yao, Jianxun Qi, Hui Feng, George F. Gao, Qihui Wang, Yi Shi, Shuguang Tan
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTCytotoxic T lymphocyte-associated antigen 4 (CTLA-4) is a critical inhibitory checkpoint molecule, and monoclonal antibodies (mAbs) targeting CTLA-4 that restore anti-tumor T cell immunity have achieved clinical success. Here, we report a hum
Externí odkaz:
https://doaj.org/article/a7f6d01c43cd47519759b8c736f47447
Autor:
Fengze Wang, Li Li, Yang Dou, Rui Shi, Xiaomin Duan, Hongchuan Liu, Jing Zhang, DanDan Liu, Jing Wu, Yang He, Jun Lan, Bai Lu, Hui Feng, Jinghua Yan
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 548-551 (2022)
The neutralizing antibody is a potential therapeutic for the ongoing COVID-19 pandemic. As an antiviral agent, numerous mAbs recognize the epitopes that overlap with ACE2-binding sites in the SARS-CoV-2-RBD. Some studies have shown that residual chan
Externí odkaz:
https://doaj.org/article/6c4076ee56804353bcf7166d10f6e8fa
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3925-3934 (2021)
T cell immunoglobulin and ITIM domain (TIGIT) is a novel immune checkpoint that has been considered as a target in cancer immunotherapy. Current available bioassays for measuring the biological activity of therapeutic antibodies targeting TIGIT are r
Externí odkaz:
https://doaj.org/article/76252f793db54e3abe1cd2d473fb156b
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Immunotherapy especially immune checkpoint inhibitors (ICIs) has brought favorable clinical results for numerous cancer patients. However, the efficacy of ICIs in colorectal cancer (CRC) is still unsatisfactory due to the poor median progression-free
Externí odkaz:
https://doaj.org/article/d78494d36f7b46fd9ee6b3ac9cff2d13
Autor:
Pengfei Li, Haitang Wu, Zhixia Zhao, Ping Du, Haitong Xu, Hongchuan Liu, Yu Zhou, Weiyue Yu, Hao Li, Lihong Liu
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Clevidipine is an ultrashort-acting dihydropyridine calcium antagonist, which can control blood pressure accurately. It is necessary to develop a liquid chromatography–tandem mass spectrometry (LC-MS/MS) method to quantitate clevidipine and its act
Externí odkaz:
https://doaj.org/article/ea1ebd11990e4109963376bf9ec765ec
Autor:
Gangling Xu, Chuanfei Yu, Wenbo Wang, Cexiong Fu, Hongchuan Liu, Yanping Zhu, Yuan Li, Chunyu Liu, Zhihao Fu, Gang Wu, Meng Li, Sha Guo, Xiaojuan Yu, Jialiang Du, Yalan Yang, Maoqin Duan, Yongfei Cui, Hui Feng, Lan Wang
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has triggered a serious public health crisis worldwide, and considering the novelty of the disease, preventative and therapeutic measures alike are urgently needed. To acce
Externí odkaz:
https://doaj.org/article/4b58bf08a1ef4ecb99be7efd904ffd8f
Publikováno v:
Advances in Materials Science and Engineering, Vol 2022 (2022)
Moisture has a significant effect on the properties of concrete, and drying concrete in an oven is a common method to obtain specimens with different moisture content. In this paper, C30 concrete specimens with different sizes were oven-dried at cons
Externí odkaz:
https://doaj.org/article/7cb31557b7624ecea80c262228740c14
Autor:
Pengfei Li, Jun Peng, Yuexin Li, Lili Gong, Yali Lv, He Liu, Tianhong Zhang, Song Yang, Hongchuan Liu, Jinglai Li, Lihong Liu
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Akebia saponin D (ASD) has a variety of biological activities and great medicinal potential, but its oral bioavailability is so low as to limit its development. Its pharmacokinetic profiles and excretion and metabolism in vivo have not be
Externí odkaz:
https://doaj.org/article/cdef13c152984de8a6e169ee61b69f54
Autor:
HONGCHUAN LIU
Publikováno v:
Scalable Computing: Practice & Experience; Sep2024, Vol. 25 Issue 5, p3259-3267, 9p
Publikováno v:
Bioanalysis. 15:269-282
Background: Aimed to simultaneously measure linezolid, voriconazole, cefoperazone and fluconazole in human plasma suitable for therapeutic drug monitoring applications, a robust, rapid and easy-to-use HPLC–MS/MS approach was developed and validated