Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Hongcang Gu"'
Autor:
Qiang Zhang, Yonghua Ding, Quanzhong Ren, Feng Zhang, Guoqiang Lyu, Tongxin Lu, Zhen Song, Qing Wang, Yongxiang Cheng, Jing Wang, Hongcang Gu
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 23, Iss 1, Pp 1-10 (2024)
Abstract Purpose Bone and joint tuberculosis (BJTB) is a distinct variant of tuberculosis in which clinical diagnosis often leads to relative misdiagnosis and missed diagnoses. This study aimed to evaluate the diagnostic accuracy of the targeted nano
Externí odkaz:
https://doaj.org/article/155dbd0c7d3d4cd596686d41b011c7ce
Autor:
Aimei Liu, Sang Liu, Kangyan Lv, Qingdong Zhu, Jun Wen, Jianpeng Li, Chengyuan Liang, Xuegang Huang, Chunming Gong, Qingfeng Sun, Hongcang Gu
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
BackgroundResistance to anti-tuberculous drugs is a major challenge in the treatment of tuberculosis (TB). We aimed to evaluate the clinical availability of nanopore-based targeted next-generation sequencing (NanoTNGS) for the diagnosis of drug-resis
Externí odkaz:
https://doaj.org/article/f6ff1b294bcb4348830fd678f48bb91d
Autor:
Shirong Zhang, Shutao He, Xin Zhu, Yunfei Wang, Qionghuan Xie, Xianrang Song, Chunwei Xu, Wenxian Wang, Ligang Xing, Chengqing Xia, Qian Wang, Wenfeng Li, Xiaochen Zhang, Jinming Yu, Shenglin Ma, Jiantao Shi, Hongcang Gu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Identifying the primary site of metastatic cancer is critical to guiding the subsequent treatment. Approximately 3–9% of metastatic patients are diagnosed with cancer of unknown primary sites (CUP) even after a comprehensive diagnostic wor
Externí odkaz:
https://doaj.org/article/9608e5d3facd4de7a19d3fd6fba5dd24
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 2, p 86 (2024)
The term ‘liquid biopsy’ has become widely used by clinicians with the development of non-invasive diagnostic and monitoring techniques for malignancies. Liquid biopsy can provide genetic information for early diagnosis, risk stratification, trea
Externí odkaz:
https://doaj.org/article/1f351d8cd81047e8b67efd8c26ddb422
Autor:
Hongying Zhang, Meng Wang, Ximei Han, Ting Wang, Yanjuan Lei, Yu Rao, Peisong Xu, Yunfei Wang, Hongcang Gu
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
ObjectivesLower respiratory tract infections (LRTIs) are one of the causes of mortality among infectious diseases. Microbial cultures commonly used in clinical practice are time-consuming, have poor sensitivity to unculturable and polymicrobial patte
Externí odkaz:
https://doaj.org/article/923dc4eb8b7848449098dd9c0c86c9a4
Autor:
Qingmei Deng, Yongqing Cao, Xiaofeng Wan, Bin Wang, Aimin Sun, Huanzhong Wang, Yunfei Wang, Hongzhi Wang, Hongcang Gu
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Cancer patients are at high risk of infections and infection-related mortality; thereby, prompt diagnosis and precise anti-infectives treatment are critical. This study aimed to evaluate the performance of nanopore amplicon sequencing in identifying
Externí odkaz:
https://doaj.org/article/f117e496ea664d42b0f46f82efeb7d25
Autor:
David Gokhman, Malka Nissim-Rafinia, Lily Agranat-Tamir, Genevieve Housman, Raquel García-Pérez, Esther Lizano, Olivia Cheronet, Swapan Mallick, Maria A. Nieves-Colón, Heng Li, Songül Alpaslan-Roodenberg, Mario Novak, Hongcang Gu, Jason M. Osinski, Manuel Ferrando-Bernal, Pere Gelabert, Iddi Lipende, Deus Mjungu, Ivanela Kondova, Ronald Bontrop, Ottmar Kullmer, Gerhard Weber, Tal Shahar, Mona Dvir-Ginzberg, Marina Faerman, Ellen E. Quillen, Alexander Meissner, Yonatan Lahav, Leonid Kandel, Meir Liebergall, María E. Prada, Julio M. Vidal, Richard M. Gronostajski, Anne C. Stone, Benjamin Yakir, Carles Lalueza-Fox, Ron Pinhasi, David Reich, Tomas Marques-Bonet, Eran Meshorer, Liran Carmel
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
How traits specific to modern humans have evolved is difficult to study. Here, Gokhman et al. compare measured and reconstructed DNA methylation maps of present-day humans, archaic humans and chimpanzees and find that genes that affect vocal tract an
Externí odkaz:
https://doaj.org/article/f72a64784f804644b521ad8a4ae77ab7
Autor:
Alessandro Pastore, Federico Gaiti, Sydney X. Lu, Ryan M. Brand, Scott Kulm, Ronan Chaligne, Hongcang Gu, Kevin Y. Huang, Elena K. Stamenova, Wendy Béguelin, Yanwen Jiang, Rafael C. Schulman, Kyu-Tae Kim, Alicia Alonso, John N. Allan, Richard R. Furman, Andreas Gnirke, Catherine J. Wu, Ari M. Melnick, Alexander Meissner, Bradley E. Bernstein, Omar Abdel-Wahab, Dan A. Landau
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
In chronic lymphocytic leukemia (CLL), evolution is driven by transcriptional and epigenetic heterogeneity. Here, the authors integrate epigenomic analyses to show how intra-tumoral epigenetic diversity results in divergent chromatin states in CLL ce
Externí odkaz:
https://doaj.org/article/84f8fc2c23c040aca441459292bfd167
Autor:
Hui Pang, Xiaowei Yu, Young Mi Kim, Xianfu Wang, Jeremy K. Jinkins, Jianing Yin, Shibo Li, Hongcang Gu
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
The subchromosomal region 1q21.1 is one of the hotspots in the human genome for deletions and reciprocal duplications, owing to the existence of hundreds of segmental duplications. Recurrent deletions and duplications in this region are thought to be
Externí odkaz:
https://doaj.org/article/b295b28e875947b2adc8a7285033ba6a
Publikováno v:
Frontiers in Pediatrics, Vol 8 (2020)
Kagami–Ogata syndrome (KOS) is a rare imprinting disorder characterized by skeletal abnormalities, dysmorphic facial features, growth retardation and developmental delay. The genetic etiology of KOS includes paternal uniparental disomy 14 [upd(14)p
Externí odkaz:
https://doaj.org/article/6c5b2cd161034f96af72108f154c2710