Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Hongbo You"'
Autor:
Tianwu Chen, Xizhuang Bai, Lunhao Bai, Wai Sin Chan, Shiyi Chen, Chen Chen, Jiwu Chen, Liaobin Chen, Guofeng Dai, Zhizeng Gao, Yang Guo, Yong Hu, Ning Hu, Huayang Huang, Xunwu Huang, Xuan Huang, Jingmin Huang, Yifan Kang, Hung Maan Lee, Hongyun Li, Yunxia Li, Jin Li, Kuanxin Li, Yanlin Li, Jian Li, Qi Li, Ruixin Lin, Xinwei Liu, Ning Liu, Wei Lü, Hongbin Lü, Xiaogang Ma, Kun Mi, Zhiming Qi, Luning Sun, Jun Tao, Xueren Teng, Xuesong Wang, Jianquan Wang, Kai Wang, Fei Wang, Hong Wang, Weiming Wang, Meng Wu, Yayi Xia, Gengyan Xing, Weidong Xu, Youjia Xu, Kun Yin, Hongbo You, Jia-Kuo Yu, Patrick Yung, Hui Zhang, Xinghuo Zhang, Xintao Zhang, Chunli Zhang, Wentao Zhang, Weiguo Zhang, Yufei Zhang, Keyuan Zhang, Yadong Zhang, Lei Zhang, Qichun Zhao, Jiapeng Zheng, Jingbin Zhou, Liwu Zhou, Yongsheng Xu
Publikováno v:
Journal of Orthopaedic Translation, Vol 48, Iss , Pp 163-175 (2024)
Background: In the recent decade, there has been substantial progress in the technologies and philosophies associated with diagnosing and treating anterior cruciate ligament (ACL) injuries in China. The therapeutic efficacy of ACL reconstruction in r
Externí odkaz:
https://doaj.org/article/24c98dedf7ca4482ab109a8bff41605d
Autor:
Rui Lu, Yunkun Qu, Zhenggang Wang, Zhiyi He, Shimeng Xu, Peng Cheng, Zhengtao Lv, Hongbo You, Fengjing Guo, Anmin Chen, Jiaming Zhang, Shuang Liang
Publikováno v:
Journal of Orthopaedic Translation, Vol 47, Iss , Pp 207-222 (2024)
Objectives: TANK-binding kinase 1 (TBK1) is pivotal in autoimmune and inflammatory diseases, yet its role in osteoarthritis (OA) remains elusive. This study sought to elucidate the effect of the TBK1 inhibitor BX795 on OA and to delineate the underly
Externí odkaz:
https://doaj.org/article/fede2b11d8404b65a820a8cbf5153851
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-12 (2023)
Abstract Osteoarthritis (OA) is defined as a degenerative joint disease that can affect all tissues of the joint, including the articular cartilage, subchondral bone, ligaments capsule, and synovial membrane. The conventional nonoperative treatments
Externí odkaz:
https://doaj.org/article/2b9aaaaab57d4069b77a828b5506af01
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-11 (2023)
Abstract Background Omega-3 polyunsaturated fatty acids (n-3 PUFAs) confers anti-inflammatory efficacy, which has been suggested to be effective for patients with osteoarthritis (OA). However, previous studies evaluating the influence of n-3 PUFAs su
Externí odkaz:
https://doaj.org/article/0a2eed9eb4db43bba20dc7bcb33a62ee
Autor:
Rui Lu, Ying-Guang Wang, Yunkun Qu, Shan-Xi Wang, Cheng Peng, Hongbo You, Wentao Zhu, Anmin Chen
Publikováno v:
Bone & Joint Research, Vol 12, Iss 4, Pp 259-273 (2023)
Aims: Osteoarthritis (OA) is a prevalent joint disorder with inflammatory response and cartilage deterioration as its main features. Dihydrocaffeic acid (DHCA), a bioactive component extracted from natural plant (gynura bicolor), has demonstrated ant
Externí odkaz:
https://doaj.org/article/8e2dec9b84224d96b5d0747e2c774266
Autor:
Yi He, Wei Wang, Haiting Zhou, Xiaojian Huang, Yinguang Wang, Yunkun Qu, Hao Cheng, Hongbo You
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Intervertebral disc degeneration, local lumbar segmental morphology changes, and atrophy of multifidus muscle have been considered to be associated with degenerative lumbar spondylolisthesis. However, there remains a great deal of controvers
Externí odkaz:
https://doaj.org/article/2aa78190b9f04b999a716ca98a403a57
Autor:
Rui Lu, Haoran Xu, Xiaofeng Deng, Yingguang Wang, Zhiyi He, Shimeng Xu, Shuang Liang, Xiaojian Huang, Hongbo You, Fengjing Guo, Peng Cheng, An-min Chen
Publikováno v:
Journal of Orthopaedic Translation, Vol 39, Iss , Pp 74-87 (2023)
Background: The incidence of intervertebral disc degeneration (IVDD) is a common degenerative disease with inflammation, decreased autophagy, and progression of fibrosis as its possible pathogenesis. Physalin A (PA) is a widely studied anti-inflammat
Externí odkaz:
https://doaj.org/article/a03e4746eef24df594908cc1f8ce1341
Autor:
Rui Lu, Zhenni Wei, Zhenggang Wang, Shimeng Xu, Kai Sun, Peng Cheng, Xiaojian Huang, Hongbo You, Fengjing Guo, Shuang Liang, An-min Chen
Publikováno v:
iScience, Vol 26, Iss 2, Pp 105936- (2023)
Summary: Osteoarthritis (OA) is a trauma-/age-related degenerative disease characterized by chronic inflammation as one of its pathogenic mechanisms. Mulberroside A (MA), a natural bioactive withanolide, demonstrates anti-inflammatory properties in v
Externí odkaz:
https://doaj.org/article/3cb5baf51f164da3a1ca2a09fb9dfa61
Autor:
Yi He, Haiting Zhou, Xiaojian Huang, Yunkun Qu, Yingguang Wang, Wenbin Pei, Rui Zhang, Sheng Chen, Hongbo You
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionTumor microenvironment (TME) has been shown to be extensively involved in tumor development. However, the dynamic change of TME components and their effects are still unclear. Here, we attempted to identify TME-related genes that could he
Externí odkaz:
https://doaj.org/article/c465bc62d5da445cac4a1626f84a533e
Autor:
Rui Lu, Zhiyi He, Weikai Zhang, Yingguang Wang, Peng Cheng, Zhengtao Lv, Xuefeng Yuan, Fengjing Guo, Hongbo You, An-min Chen, Weihua Hu
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundOsteoarthritis (OA) is a common aging-related degenerative joint disease with chronic inflammation as its possible pathogenesis. Oroxin B (OB), a flavonoid isolated from traditional Chinese herbal medicine, possesses anti-inflammation prope
Externí odkaz:
https://doaj.org/article/ccfb77cf2b3c4629851e5810c4fc1b5d