Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hongbo, Men"'
Autor:
Xiang Wang, Xinxin Chen, Wenqian Zhou, Hongbo Men, Terigen Bao, Yike Sun, Quanwei Wang, Yi Tan, Bradley B. Keller, Qian Tong, Yang Zheng, Lu Cai
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 2, Pp 708-722 (2022)
Herein, we define the role of ferroptosis in the pathogenesis of diabetic cardiomyopathy (DCM) by examining the expression of key regulators of ferroptosis in mice with DCM and a new ex vivo DCM model. Advanced glycation end-products (AGEs), an impor
Externí odkaz:
https://doaj.org/article/671ecb597711419db3f96eba8c32435d
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Physiological reactive oxygen species (ROS) are important regulators of intercellular signal transduction. Oxidative and antioxidation systems maintain a dynamic balance under physiological conditions. Increases in ROS levels destroy the dynamic bala
Externí odkaz:
https://doaj.org/article/183b6dd814e44caeb8017f267dc17df8
Autor:
Quanwei Wang, Bradley B. Keller, Yang Zheng, Qian Tong, Terigen Bao, Wenqian Zhou, Lu Cai, Hongbo Men, Yike Sun, Xiang Wang, Yi Tan, Xinxin Chen
Publikováno v:
Acta Pharmaceutica Sinica B. 12:708-722
Herein, we define the role of ferroptosis in the pathogenesis of diabetic cardiomyopathy (DCM) by examining the expression of key regulators of ferroptosis in mice with DCM and a new ex vivo DCM model. Advanced glycation end-products (AGEs), an impor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35a18ee4cf845220e1e31f338b67b79f
https://doi.org/10.1016/j.apsb.2021.10.005
https://doi.org/10.1016/j.apsb.2021.10.005
Publikováno v:
International Journal of Biological Sciences. 18:970-982
Caspase recruitment domain-containing protein 9 (CARD9) is an adaptor protein expressed on myeloid cells and located downstream of pattern recognition receptors (PRRs), which transduces signals involved in innate immunity. CARD9 deficiency is associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2477a34990e61cfe0db25b349586f9
https://doi.org/10.7150/ijbs.65979
https://doi.org/10.7150/ijbs.65979
Publikováno v:
Journal of Cellular and Molecular Medicine
To efficiently prevent diabetic cardiomyopathy (DCM), we have explored and confirmed that metallothionein (MT) prevents DCM by attenuating oxidative stress, and increasing expression of proteins associated with glucose metabolism. To determine whethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691d2ce820ee29f3805182f9dfbf078b
http://europepmc.org/articles/PMC8278119
http://europepmc.org/articles/PMC8278119
Publikováno v:
International Journal of Biological Sciences
Mediator complex subunit 13 (MED13, previously known as THRAP1 and TRAP240) is a subunit of the cyclin-dependent kinase 8 (CDK8) kinase module in the eukaryotic mediator complex. MED13 has been known to play critical roles in cell cycle, development,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef86776e86c96c2410f986a3eea32f9c
https://doi.org/10.7150/ijbs.52290
https://doi.org/10.7150/ijbs.52290
Publikováno v:
Cellular and Molecular Life Sciences. 78:2001-2018
Cardiovascular disease (CVD) remains the leading cause of mortality globally, so further investigation is required to identify its underlying mechanisms and potential targets for its prevention. The transcription factor p53 functions as a gatekeeper,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cab4eac871c89de762e0b88a21d4fe98
https://doi.org/10.1007/s00018-020-03694-6
https://doi.org/10.1007/s00018-020-03694-6
Publikováno v:
Experimental and Therapeutic Medicine
The relationship between cancer and heart failure has been extensively studied in the last decade. These studies have focused on describing heart injury caused by certain cancer treatments, including radiotherapy, chemotherapy and targeted therapy. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f8f7be12a332626f3ab016e679754f
https://doi.org/10.3892/etm.2021.10898
https://doi.org/10.3892/etm.2021.10898
Autor:
Wenqian Zhou, Jamie L. Young, Hongbo Men, Haina Zhang, Haitao Yu, Qian Lin, He Xu, Jianxiang Xu, Yi Tan, Yang Zheng, Lu Cai
Publikováno v:
The Science of the total environment. 809
We previously showed the development of cardiac remodeling (hypertrophy or fibrosis) in mice with either post-weaning high-fat diet (HFD, 60% kcal fat) feeding or exposure to chronic low-dose cadmium. Here, we determined whether whole-life exposure t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a7b8df0305d78d1a5376dea0e1d7ddf
https://pubmed.ncbi.nlm.nih.gov/34875320
https://pubmed.ncbi.nlm.nih.gov/34875320
Publikováno v:
Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 12 (2021)
Frontiers in Endocrinology, Vol 12 (2021)
Physiological reactive oxygen species (ROS) are important regulators of intercellular signal transduction. Oxidative and antioxidation systems maintain a dynamic balance under physiological conditions. Increases in ROS levels destroy the dynamic bala
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b73e190a25785ab05ebe204edc3eed