Zobrazeno 1 - 10
of 981
pro vyhledávání: '"Hongbing, Zhang"'
Publikováno v:
Meikuang Anquan, Vol 55, Iss 10, Pp 214-220 (2024)
To solve the problem of serious pollution and dust accumulation under the traditional mixed ventilation of the fully mechanized excavation face, the idea of using the air flow control device of the air outlet and the jet air curtain of the exhaust ou
Externí odkaz:
https://doaj.org/article/d55670ccc76e49a8a8b1d9b253af15e8
Autor:
Shuyun Zhao, Shuai Hao, Jiasheng Zhou, Xinran Chen, Tianhua Zhang, Zhaolai Qi, Ting Zhang, Sajid Jalal, Chuanxin Zhai, Lu Yin, Yufei Bo, Hongming Teng, Yue Wang, Dongyan Gao, Hongbing Zhang, Lin Huang
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-17 (2024)
Abstract Background Patients with tuberous sclerosis complex (TSC) develop renal cysts and/or angiomyolipomas (AMLs) due to inactive mutations of either TSC1 or TSC2 and consequential mTOR hyperactivation. The molecular events between activated mTOR
Externí odkaz:
https://doaj.org/article/b9949ffce8544f0a9fbed3a7b5573e82
Autor:
Zihe Zhang, Yongwen Li, Ruifeng Shi, Chaoyi Jia, Songlin Xu, Guangsheng Zhu, Peijun Cao, Hua Huang, Xuanguang Li, Hongbing Zhang, Minghui Liu, Chen Chen, Hongyu Liu, Chunsheng Kang, Jun Chen
Publikováno v:
Cell Death and Disease, Vol 15, Iss 9, Pp 1-14 (2024)
Abstract Osimertinib is a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (EGFR-TKI) approved for patients with EGFR T790M resistance mutations as first- or second-line treatment of EGFR-positive patients. Resistanc
Externí odkaz:
https://doaj.org/article/6cd58d2ae3984a0ea93766d76679bcb3
Autor:
Guangsheng Zhu, Yanan Wang, Yingjie Wang, Hua Huang, Boshi Li, Peijie Chen, Chen Chen, Hongbing Zhang, Yongwen Li, Hongyu Liu, Jun Chen
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-13 (2024)
Abstract Lung cancer is a leading cause of cancer-related mortality globally, with a dismal 5-year survival rate, particularly for Lung Adenocarcinoma (LUAD). Mechanical changes within the tumor microenvironment, such as extracellular matrix (ECM) re
Externí odkaz:
https://doaj.org/article/0e3e54da3a96473ea73b41bcc6512931
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
PurposeThis research intends to investigate the treatment of non-small cell lung cancer (NSCLC) using Toripalimab, focusing on its effectiveness and safety profile. Efficacy refers to the survival prognosis, while safety pertains to the occurrence of
Externí odkaz:
https://doaj.org/article/95fe3df6de374cb9bd7f49f110b19d39
Autor:
Zixi Wang, Huaiyuan Zong, Weiwei Liu, Wei Lin, Anjiang Sun, Zhao Ding, Xu Chen, Xiaofeng Wan, Yanyan Liu, Zhongdong Hu, Hongbing Zhang, Hongwu Li, Yehai Liu, Dapeng Li, Sumei Zhang, Xiaojun Zha
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-22 (2024)
Abstract Background The dysregulated mechanistic target of rapamycin complex 1 (mTORC1) signaling plays a critical role in ferroptosis resistance and tumorigenesis. However, the precise underlying mechanisms still need to be fully understood. Methods
Externí odkaz:
https://doaj.org/article/bddf02bc52074441a2ce5fd662fbebd1
Autor:
Fuqiang Huang, Jing Guo, Na Zhao, Mengjie Hou, Xiaochen Gai, Shuhui Yang, Pei Cai, Yanan Wang, Qian Ma, Qi Zhao, Li Li, Huayu Yang, Yanling Jing, Di Jin, Zhongdong Hu, Xiaojun Zha, Hongyang Wang, Yilei Mao, Fangming Liu, Hongbing Zhang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background Although hepatitis B virus (HBV) infection is a major risk factor for hepatic cancer, the majority of HBV carriers do not develop this lethal disease. Additional molecular alterations are thus implicated in the process of liver tu
Externí odkaz:
https://doaj.org/article/fcae3e2c4b5f427887e202af29fbad5f
Autor:
Fangming Liu, Yuting Wu, Baohui Zhang, Shuhui Yang, Kezhuo Shang, Jie Li, Pengju Zhang, Weiwei Deng, Linlin Chen, Liang Zheng, Xiaochen Gai, Hongbing Zhang, Jing Ni
Publikováno v:
Chinese Medical Journal, Vol 137, Iss 2, Pp 181-189 (2024)
Abstract. Background:. Liver cancer is largely resistant to chemotherapy. This study aimed to identify the effective chemotherapeutics for β-catenin-activated liver cancer which is caused by gain-of-function mutation of catenin beta 1 (CTNNB1), the
Externí odkaz:
https://doaj.org/article/a44d8ab78eb44fd2b839a2b9b0332a41
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 2, Pp 309-315 (2024)
Macrophage migration inhibitory factor (MIF), a multifunctional cytokine, is secreted by various cells and participates in inflammatory reactions, including innate and adaptive immunity. There are some evidences that MIF is involved in many vitreoret
Externí odkaz:
https://doaj.org/article/650bc3313e0047faabe713f7df2d2e8e
Publikováno v:
环境与职业医学, Vol 40, Iss 12, Pp 1411-1418 (2023)
BackgroundNoise and dust are the most widespread occupational hazards. Animal studies have shown that they may cause impaired fasting glucose (IFG) by disturbing glucose metabolism and impairing the function of pancreatic islet cells, which can lead
Externí odkaz:
https://doaj.org/article/d860313f44df41f199205fd42bd73d8c