Zobrazeno 1 - 10
of 186
pro vyhledávání: '"Hongbin, Han"'
Autor:
Tianhao Mei, Ying Chen, Yajuan Gao, Hang Zhao, Xingzhou Lyu, Jing Lin, Tianye Niu, Hongbin Han, Zhiqian Tong
Publikováno v:
npj Microgravity, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract During space flight, prolonged weightlessness stress exerts a range of detrimental impacts on the physiology and psychology of astronauts. These manifestations encompass depressive symptoms, anxiety, and impairments in both short-term memory
Externí odkaz:
https://doaj.org/article/0dc218d535d04f43816a0bbbc980eb01
Publikováno v:
Health Data Science, Vol 4 (2024)
Background: MRI segmentation offers crucial insights for automatic analysis. Although deep learning-based segmentation methods have attained cutting-edge performance, their efficacy heavily relies on vast sets of meticulously annotated data. Methods:
Externí odkaz:
https://doaj.org/article/77332cbdba9c44919e1d6d572044d95b
Publikováno v:
Frontiers in Marine Science, Vol 10 (2023)
Since 2015, the coastal waters of Qinhuangdao in Hebei province, China have experienced green tide disasters for consecutive years. Resource utilization is an important measure for preventing and controlling green tides. To comprehensively utilize gr
Externí odkaz:
https://doaj.org/article/889c90dad1c44ad4b9a55f9c58434927
Autor:
Nan Niu, Fang Qiu, Qianshi Xu, Guijin He, Xi Gu, Wenbin Guo, Dianlong Zhang, Zhigao Li, Yi Zhao, Yong Li, Ke Li, Hao Zhang, Peili Zhang, Yuanxi Huang, Gangling Zhang, Hongbin Han, Zhengang Cai, Pengfei Li, Hong Xu, Guanglei Chen, Jinqi Xue, Xiaofan Jiang, Alireza Hamidian Jahromi, Jinshi Li, Yu Zhao, Eduardo de Faria Castro Fleury, Shiwen Huo, Huajun Li, Guy Jerusalem, Domenico Tripodi, Tong Liu, Xinyu Zheng, Caigang Liu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Neoadjuvant therapy is recommended for patients with locally advanced breast cancer. Here the authors report the results of a phase 2 clinical trial of oral neoadjuvant therapy with pyrotinib (pan-HER tyrosine kinase inhibitor), letrozole (aromatase
Externí odkaz:
https://doaj.org/article/1d9c37ba0fbf4148af08531c29508fb7
Publikováno v:
npj Digital Medicine, Vol 5, Iss 1, Pp 1-13 (2022)
Abstract The mobile health (mHealth) industry is an enormous global market; however, the dropout or continuance of mHealth is a major challenge that is affecting its positive outcomes. To date, the results of studies on the impact factors have been i
Externí odkaz:
https://doaj.org/article/36dd69815e8040d99ab2961bd4587f2e
Publikováno v:
Digital Health, Vol 9 (2023)
Objectives In solving the global challenge of sleep disorders, Mobile Health app is one of the important means to monitor, diagnose, and intervene in sleep disorders. This study aims to (1) summarize the status and trends of research in this field; (
Externí odkaz:
https://doaj.org/article/2568658acb1942248e828681d2240e53
Autor:
Kun Shang, Lingpu Zhang, Yingjie Yu, Haihua Xiao, Yajuan Gao, Liu Yang, Jia Huang, Haiqin Song, Hongbin Han
Publikováno v:
Materials Today Bio, Vol 18, Iss , Pp 100548- (2023)
USP1 (Ubiquitin-specific protease 1) is closely related to the prognosis of patients with liver cancer and plays an important role in DNA damage repair. C527 is a selective USP1 inhibitor (USP1i), which can regulate the protein ubiquitination to effe
Externí odkaz:
https://doaj.org/article/ddb13d7aa8c847e3bbf1c2e0dc4304b6
Autor:
Mingfu Nuo, Shaojiang Zheng, Qinglian Wen, Hongjuan Fang, Tong Wang, Jun Liang, Hongbin Han, Jianbo Lei
Publikováno v:
Journal of Medical Internet Research, Vol 25, p e42856 (2023)
BackgroundSleep disorders are a global challenge, affecting a quarter of the global population. Mobile health (mHealth) sleep apps are a potential solution, but 25% of users stop using them after a single use. User satisfaction had a significant impa
Externí odkaz:
https://doaj.org/article/c218d37221804094a67bca094c699bba
Autor:
Lingpu Zhang, Lin Zhu, Lin Tang, Jiayi Xie, Yajuan Gao, Changyuan Yu, Kun Shang, Hongbin Han, Chaoyong Liu, Yunfeng Lu
Publikováno v:
Advanced Science, Vol 10, Iss 3, Pp n/a-n/a (2023)
Abstract Camptothecin (CPT) is a potent chemotherapeutic agent for various cancers, but the broader application of CPT is still hindered by its poor bioavailability and systemic toxicity. Here, a prodrug that releases CPT in response to glutathione (
Externí odkaz:
https://doaj.org/article/04e7bdc84b844aa0bcb71427e4b16b77
Publikováno v:
The Lancet Regional Health. Americas, Vol 17, Iss , Pp 100421- (2023)
Externí odkaz:
https://doaj.org/article/47cccfa262604b62ae77267bc98af4c4