Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hong-he Liu"'
G-quadruplexes offer a conserved structural motif for NONO recruitment to NEAT1 architectural lncRNA
Autor:
Adan Velasquez, Tao Zhang, Shraddha Teli, Jiou Wang, Hong-he Liu, Eric A J Simko, Aaron R. Haeusler
Publikováno v:
Nucleic Acids Research
The long non-coding RNA NEAT1 serves as a scaffold for the assembly of paraspeckles, membraneless nuclear organelles involved in gene regulation. Paraspeckle assembly requires NEAT1 recruitment of the RNA-binding protein NONO, however the NEAT1 eleme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9157b11095d0523aeeac47bfd17238d3
https://doi.org/10.1093/nar/gkaa475
https://doi.org/10.1093/nar/gkaa475
Publikováno v:
Nucleic Acids Research
DNA supercoiling is an important regulator of gene activity. The transmission of transcription-generated supercoiling wave along a DNA helix provides a way for a gene being transcribed to communicate with and regulate its neighboring genes. Currently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a82ef308a0c586385d691f4c90c96406
https://doi.org/10.1093/nar/gky534
https://doi.org/10.1093/nar/gky534
Publikováno v:
ACS Chemical Biology. 12:2609-2618
Transcription induces formation of intramolecular G-quadruplex structures at the upstream region of a DNA duplex by an upward transmission of negative supercoiling through the DNA. Currently the regulation of such G-quadruplex formation remains uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ed05274aca02ea6f3e822300d6b7dc5
https://doi.org/10.1021/acschembio.7b00435
https://doi.org/10.1021/acschembio.7b00435
Autor:
Daisuke Murata, Hong-he Liu, Sungtaek Oh, Chan Hyun Na, Jiou Wang, Kie Itoh, Tao Wang, Hiromi Sesaki, Thomas Hartung, Liang Zhao
Publikováno v:
Cell Metab
The haploinsufficiency of C9orf72 is implicated in the most common forms of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), but the full spectrum of C9orf72 functions remains to be established. Here, we report that C9orf72 is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::932468d2488b166a74d3d4af1e6c6de5
https://pubmed.ncbi.nlm.nih.gov/33545050
https://pubmed.ncbi.nlm.nih.gov/33545050
Autor:
Yon Ju Ji, Scott Bailey, Kenji Johnson, Mingming Liu, Kaitlin Johnson, Hong-he Liu, Yu Ning Lu, Yongwon Suk, Yang Liu, Jiou Wang, Tao Wang
Publikováno v:
Genesdevelopment. 32(21-22)
Cells undergo metabolic adaptation during environmental changes by using evolutionarily conserved stress response programs. This metabolic homeostasis is exquisitely regulated, and its imbalance could underlie human pathological conditions. We report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3bc809ab84fc9780ad8001a46f157c7
https://pubmed.ncbi.nlm.nih.gov/30767689
https://pubmed.ncbi.nlm.nih.gov/30767689
Publikováno v:
Chemical Science
RNA G-quadruplex formation in a defined sequence in living bacterial cells is detected by bimolecular fluorescence complementation with sequence and structure specificity.
G-quadruplexes are implicated in many essential cellular processes and se
G-quadruplexes are implicated in many essential cellular processes and se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73dccdef34e6f1840f6e3ac630923a2b
https://doi.org/10.1039/c5sc03946k
https://doi.org/10.1039/c5sc03946k
Autor:
Lin Guo, Goran Periz, Patrick C. Mullane, James Shorter, Jiou Wang, Hong-he Liu, Shao En Ong, Amelia F. Alessi, Ho Yon Hwang, Elad Elkayam, Amirhossein Ghanbari Niaki, John Kim, Yen Ching Wu, Amit Arora, Hejia Wang, Sua Myong, Lu He, Yon Ju Ji, Anthony K.L. Leung, Tao Zhang, Leemor Joshua-Tor
Publikováno v:
Molecular cell. 69(5)
MicroRNA-mediated gene silencing is a fundamental mechanism in the regulation of gene expression. It remains unclear how the efficiency of RNA silencing could be influenced by RNA-binding proteins associated with the microRNA-induced silencing comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a318f971d5a3ebf7eebcc8675665dea
https://pubmed.ncbi.nlm.nih.gov/29499134
https://pubmed.ncbi.nlm.nih.gov/29499134
Publikováno v:
Nucleic Acids Research
G-quadruplexes, four-stranded structures formed by Guanine-rich nucleic acids, are implicated in many physiological and pathological processes. G-quadruplex-forming sequences are abundant in genomic DNA, and G-quadruplexes have recently been shown to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c105d47a664e40a0783d6019d99fec16
http://europepmc.org/articles/PMC3737545
http://europepmc.org/articles/PMC3737545
Autor:
Jia-yu Zhang, Xin-min Li, Zheng Tan, Yi-de He, Bi-Feng Yuan, Ke-wei Zheng, Hong-he Liu, Yu-hua Hao
G-quadruplex structures formed by guanine-rich nucleic acids are implicated in essential physiological and pathological processes and nanodevices. G-quadruplexes are normally composed of four Gn (n ≥ 3) tracts assembled into a core of multiple stac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::911fd017b43867896510a15f0e7e63fd
https://europepmc.org/articles/PMC4664295/
https://europepmc.org/articles/PMC4664295/
Publikováno v:
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]. 47(7)
We aimed to establish a sensitive quantified method for the simultaneous determination of melamine and cyanuric acid residues in water and urine by hydrophilic interaction liquid chromatography coupled with electrospray tandem mass spectrometry (HILI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ad5b01001dbeeb36d00c28af08b4360
https://pubmed.ncbi.nlm.nih.gov/24304959
https://pubmed.ncbi.nlm.nih.gov/24304959