Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Hong-fen Guo"'
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundDevelopment of successful antibody-based immunotherapeutic and radioimmunotherapeutic strategies rely on the identification of cell surface tumor-associated antigens (TAA) with restricted expression on normal tissues. Desmoplastic small rou
Externí odkaz:
https://doaj.org/article/679164f905264f2cb89d6a6c7abaf612
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 3 (2023)
Background Success of T cell immunotherapy hinges on the tumor microenvironment (TME), and abnormal tumor vasculature is a hallmark of most solid tumors and associated with immune evasion. The efficacy of T cell engaging bispecific antibody (BsAb) tr
Externí odkaz:
https://doaj.org/article/17ef157b8e354f31898832bfc06a22de
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/1417a766f63b4510809ccc4f8117efda
Autor:
Madelyn Espinosa-Cotton, Sayed Shahabuddin Hoseini, Hong-fen Guo, Nai-Kong V Cheung, Yi Feng, Mallika Vadlamudi, Hoa Tran, Irene Cheung
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Background Acute myeloid leukemia (AML) remains one of the most challenging hematological malignancies. Despite progress in therapeutics, majority of patients succumb to this neoplasm. CD33 is a proven therapeutic target, given its expression on most
Externí odkaz:
https://doaj.org/article/2b7364e3683249408f5bae5eadc73c5c
Publikováno v:
Stem Cell Research, Vol 15, Iss 2, Pp 419-426 (2015)
Neuroblastoma, a malignancy of multipotent embryonic neural crest cells, is the most common extracranial solid cancer in childhood and most common cancer in infancy. Cellular phenotype has been shown to be an important determinant of the malignant po
Externí odkaz:
https://doaj.org/article/d3d2e8d779134a85b38919f567ef1782
Autor:
Jeanette D. Walton, David R. Kattan, Sharon K. Thomas, Barbara A. Spengler, Hong-Fen Guo, June L. Biedler, Nai-Kong V. Cheung, Robert A. Ross
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 6, Iss 6, Pp 838-845 (2004)
Cellular heterogeneity is a hallmark of human neuroblastoma tumors and cell lines. Within a single neuroblastoma are cells from distinct neural crest lineages whose relative abundance is significant for prognosis. We postulate that a self-renewing mu
Externí odkaz:
https://doaj.org/article/3d82b77190214067a8f8a24165bf19e2
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63359 (2013)
Ganglioside GD2 is a cell surface glycolipid that is highly expressed on cancer cells of neuroectodermal origin, including neuroblastoma, retinoblastoma, melanoma, sarcomas, brain tumors and small cell lung cancer. Monoclonal antibodies (MoAb) that t
Externí odkaz:
https://doaj.org/article/3cb65e90811e4ea2b1ccebc1c107c4ee
Publikováno v:
Journal of Visualized Experiments.
Autor:
Sarah M. Cheal, Steven M. Larson, Nai Kong V. Cheung, Neeta Pandit-Taskar, Achim Jungbluth, Andrea Cercek, Garrett M. Nash, Sébastien Monette, Pat B. Zanzonico, Brian H. Santich, Hong-fen Guo, Hong Xu, Mitesh Patel, Daniela Burnes Vargas, Blesida Punzalan, Edward K. Fung, Darren R. Veach, Sebastian K. Chung, Meghan M. Bell, Christopher S. Chandler
Peritoneal carcinomatosis (PC) is considered incurable, and more effective therapies are needed. Herein we test the hypothesis that GPA33-directed intracompartmental pretargeted radioimmunotherapy (PRIT) can cure colorectal peritoneal carcinomatosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acef59b9b8016bb1ef603c3ce50fbe38
https://doi.org/10.1158/1535-7163.c.6543270.v1
https://doi.org/10.1158/1535-7163.c.6543270.v1
Figure S4 shows the result of CD45RO and CD25 staining using cells from TDCC assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::008d1dab6bd4aaaa961c147148d6db46
https://doi.org/10.1158/1535-7163.22505382.v1
https://doi.org/10.1158/1535-7163.22505382.v1