Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Hong-Xue Chen"'
Autor:
Jing, Wen, Jian-Wu, Zhang, Yuan-Xia, Lyu, Hui, Zhang, Kai-Xi, Deng, Hong-Xue, Chen, Ying, Wei
Publikováno v:
Chinese Journal of Integrative Medicine. 29:325-332
To evaluate the antidiarrheal effect of ethanol extract of Glycyrrhiza uralensis Fisch root (GFR) in vivo and jejunal contraction in vitro.In vivo, 50 mice were divided into negative control, positive control (verapamil), low-, medium- and high-dose
Publikováno v:
Organic & Biomolecular Chemistry. 17:2099-2102
We report a facile synthetic strategy toward CH2-substituted phosphothreonine mimetics. Herein, inexpensive valine with a directing group was converted into homothreonine via palladium-catalyzed γ-methyl C(sp3)–H bond activation, followed by const
Autor:
Hua-Zhen Duan, Hong-Xue Chen, Yan-Mei Li, Yun-Lai Zhang, Jie Kang, Rong Chang, Yong-Xiang Chen
Publikováno v:
Organic Letters. 20:3278-3281
A novel and facile synthetic strategy for α,α-difluorinated phosphonate mimetics of phosphoserine/phosphothreonine utilizing rhodium-catalyzed asymmetric hydrogenation was developed. The dehydrogenated substrate β-difluorophosphonomethyl α-(acyla
Autor:
Fang-Yi Li, Hong-Xue Chen, Benjamin Sperlich, Katrin Weise, Roland Winter, Yan-Mei Li, Yong-Xiang Chen, Samy Al-Ayoubi, Si-Yu Zhang, Yufen Zhao
Publikováno v:
ACS Chemical Biology. 12:1703-1710
K-Ras4B is one of the most frequently mutated Ras isoforms in cancer. The signaling activity of K-Ras4B depends on its localization to the plasma membrane (PM), which is mainly mediated by its polybasic farnesylated C-terminus. On top of the constitu
Publikováno v:
Organicbiomolecular chemistry. 17(8)
We report a facile synthetic strategy toward CH2-substituted phosphothreonine mimetics. Herein, inexpensive valine with a directing group was converted into homothreonine via palladium-catalyzed γ-methyl C(sp3)-H bond activation, followed by constru
Autor:
Si-Qi Huang, Jie Kang, Yan-Mei Li, Yun-Lai Zhang, Yong-Xiang Chen, Rong Chang, Fang-Yi Li, Hong-Xue Chen
Publikováno v:
Tetrahedron Letters. 58:2551-2553
Phosphatase-inert peptidomimetics containing phosphonate pSer analogue have been developed as valuable biological tools for probing and regulating pSer-dependent protein-protein interactions (PPIs) in cellular context. Herein, we report a facile and
Autor:
Hong-Xue Chen, Jie Kang, Rong Chang, Yun-Lai Zhang, Hua-Zhen Duan, Yan-Mei Li, Yong-Xiang Chen
Publikováno v:
Organic Letters; 6/1/2018, Vol. 20 Issue 11, p3278-3281, 4p