Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Hong-Xia Tian"'
Autor:
Hong‐xia Tian, Zhi‐hong Chen, Guang‐Ling Jie, Zhen Wang, Hong‐hong Yan, Si‐pei Wu, Shui‐lian Zhang, Dan‐xia Lu, Xu‐chao Zhang, Yi‐long Wu
Publikováno v:
Cancer Medicine, Vol 12, Iss 1, Pp 396-406 (2023)
Abstract Objective NF1 is a tumor suppressor gene that encodes the neurofibromin protein and negatively regulates Ras signaling. This study was aimed to investigate the molecular, clinical characteristics, and prognostic features of NF1 gene in EGFR
Externí odkaz:
https://doaj.org/article/e5f7395017c04009a1b841fdf49f70cf
Autor:
Guang-Ling Jie, Lun-Xi Peng, Mei-Mei Zheng, Hao Sun, Song-Rong Wang, Si-Yang Maggie Liu, Kai Yin, Zhi-Hong Chen, Hong-Xia Tian, Jin-Ji Yang, Xu-Chao Zhang, Hai-Yan Tu, Qing Zhou, Catherine C. L. Wong, Yi-Long Wu
Publikováno v:
Cancers, Vol 15, Iss 1, p 302 (2023)
MET inhibitors have shown promising efficacy for MET-dysregulated non-small cell lung cancer (NSCLC). However, quite a few patients cannot benefit from it due to the lack of powerful biomarkers. This study aims to explore the potential role of plasma
Externí odkaz:
https://doaj.org/article/32700ef873ae4300add7ca7225550022
Autor:
Hong-Xia Tian, Xu-Chao Zhang, Zhen Wang, Jin-Ji Yang, Wei-Bang Guo, Zhi-Hong Chen, Yi-Long Wu
Publikováno v:
Chinese Medical Journal, Vol 130, Iss 12, Pp 1446-1453 (2017)
Background: Drug resistance to targeted therapies occurs in lung cancer, and resistance mechanisms related to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are continuously being discovered. We aimed to establish a novel m
Externí odkaz:
https://doaj.org/article/c14f5df97e7d4e04a6a541562b837a54
Publikováno v:
Protein & Cell, Vol 7, Iss 10, Pp 699-713 (2016)
ABSTRACT Mitochondria play a key role in various cell processes including ATP production, Ca2 + homeostasis, reactive oxygen species (ROS) generation, and apoptosis. The selective removal of impaired mitochondria by autophagosome is known as mitophag
Externí odkaz:
https://doaj.org/article/32adcb7066634cbf8d93dda37ed3c3d4
Autor:
Hong-Xia Tian, Xu-Chao Zhang, Zhen Wang, Jian-Guang Chen, Shi-Liang Chen, Wei-Bang Guo, Yi-Long Wu
Publikováno v:
Cancer Biology & Medicine, Vol 13, Iss 1, Pp 68-76 (2016)
Objective: This study aims to establish a method for highly parallel multiplexed detection of genetic mutations in Chinese lung cancer samples through Agena iPLEX chemistry and matrix-assisted laser desorption ionization time-of-flight analysis on Ma
Externí odkaz:
https://doaj.org/article/4f7b3ead94694ceab53734db996033a1
Autor:
Hong‐xia Tian, Zhi‐hong Chen, Guang‐Ling Jie, Zhen Wang, Hong‐hong Yan, Si‐pei Wu, Shui‐lian Zhang, Dan‐xia Lu, Xu‐chao Zhang, Yi‐long Wu
Publikováno v:
Cancer Medicine. 12:396-406
NF1 is a tumor suppressor gene that encodes the neurofibromin protein and negatively regulates Ras signaling. This study was aimed to investigate the molecular, clinical characteristics, and prognostic features of NF1 gene in EGFR mutant lung cancer
Autor:
Yi-Long Wu, Tony S. Mok, Ri-Qiang Liao, Qiang Nie, Wen-Zhao Zhong, Xue-Ning Yang, Bin-Chao Wang, Zhen Wang, Ben-Yuan Jiang, Yi-Sheng Huang, Hua-Jun Chen, Zhi Xie, Hong-Xia Tian, Qing Zhou, Chong-Rui Xu, Jian Su, Xu-Chao Zhang, Jin-Ji Yang
PDF file - 253KB, Representative IHC graphs of EGFR, p-EGFR, ALK, p-ALK in EGFR-mutant/ALK-negative, EGFR-WT/ALK-positive tumors, and EGFR-WT/ALK-negative tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b43deb1ee170625da6390299c1445ce7
https://doi.org/10.1158/1078-0432.22448814
https://doi.org/10.1158/1078-0432.22448814
Autor:
Yi-Long Wu, Tony S. Mok, Ri-Qiang Liao, Qiang Nie, Wen-Zhao Zhong, Xue-Ning Yang, Bin-Chao Wang, Zhen Wang, Ben-Yuan Jiang, Yi-Sheng Huang, Hua-Jun Chen, Zhi Xie, Hong-Xia Tian, Qing Zhou, Chong-Rui Xu, Jian Su, Xu-Chao Zhang, Jin-Ji Yang
Purpose: We investigated the incidence of concomitant epidermal growth factor receptor (EGFR) mutations and anaplastic lymphoma kinase (ALK) rearrangements in Chinese patients with non–small cell lung cancer (NSCLC), and assessed responses to EGFR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b5bf599c0d2471615854e52eb98e91
https://doi.org/10.1158/1078-0432.c.6521490.v1
https://doi.org/10.1158/1078-0432.c.6521490.v1
Autor:
Yi-Long Wu, Tony S. Mok, Ri-Qiang Liao, Qiang Nie, Wen-Zhao Zhong, Xue-Ning Yang, Bin-Chao Wang, Zhen Wang, Ben-Yuan Jiang, Yi-Sheng Huang, Hua-Jun Chen, Zhi Xie, Hong-Xia Tian, Qing Zhou, Chong-Rui Xu, Jian Su, Xu-Chao Zhang, Jin-Ji Yang
PDF file - 63KB.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::324c6b56ed1788b9ab27785ba5e56f2b
https://doi.org/10.1158/1078-0432.22448811.v1
https://doi.org/10.1158/1078-0432.22448811.v1
Autor:
Yi-Long Wu, Tony S. Mok, Ri-Qiang Liao, Qiang Nie, Wen-Zhao Zhong, Xue-Ning Yang, Bin-Chao Wang, Zhen Wang, Ben-Yuan Jiang, Yi-Sheng Huang, Hua-Jun Chen, Zhi Xie, Hong-Xia Tian, Qing Zhou, Chong-Rui Xu, Jian Su, Xu-Chao Zhang, Jin-Ji Yang
PDF file - 635KB, Sequence results of EML4-ALK fusion variants.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72461fc2e5f95ebf7ffdb600ff3c8c21
https://doi.org/10.1158/1078-0432.22448817
https://doi.org/10.1158/1078-0432.22448817