Zobrazeno 1 - 10
of 1 062
pro vyhledávání: '"Hong-Wen Deng"'
Autor:
Anjum Shaik, Kristoffer Larsen, Nancy E. Lane, Chen Zhao, Kuan-Jui Su, Joyce H. Keyak, Qing Tian, Qiuying Sha, Hui Shen, Hong-Wen Deng, Weihua Zhou
Publikováno v:
Bone Reports, Vol 22, Iss , Pp 101805- (2024)
Hip fractures present a significant healthcare challenge, especially within aging populations, where they are often caused by falls. These fractures lead to substantial morbidity and mortality, emphasizing the need for timely surgical intervention. D
Externí odkaz:
https://doaj.org/article/72ff07d14f2343cf963820df19849a0d
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
Although DNA methylation (DNAm) has been implicated in the pathogenesis of numerous complex diseases, from cancer to cardiovascular disease to autoimmune disease, the exact methylation sites that play key roles in these processes remain elusive. One
Externí odkaz:
https://doaj.org/article/ce4c8e39384040168a51e23a5c1425e9
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-16 (2024)
Abstract Accurate prognosis for cancer patients can provide critical information for optimizing treatment plans and improving life quality. Combining omics data and demographic/clinical information can offer a more comprehensive view of cancer progno
Externí odkaz:
https://doaj.org/article/8f18583803f14a7dacc3fdd578081d36
Autor:
Jingjing Zhu, Shuai Liu, Keenan A. Walker, Hua Zhong, Dalia H. Ghoneim, Zichen Zhang, Praveen Surendran, Sarah Fahle, Adam Butterworth, Md Ashad Alam, Hong-Wen Deng, Chong Wu, Lang Wu
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Specific peripheral proteins have been implicated to play an important role in the development of Alzheimer’s disease (AD). However, the roles of additional novel protein biomarkers in AD etiology remains elusive. The availabili
Externí odkaz:
https://doaj.org/article/9809b45fd9a347d1b2f020ba0d3123a1
Autor:
Wei-Wei Pang, Yi-Sheng Cai, Chong Cao, Fu-Rong Zhang, Qin Zeng, Dan-Yang Liu, Ning Wang, Xiao-Chao Qu, Xiang-Ding Chen, Hong-Wen Deng, Li-Jun Tan
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundThe immune microenvironment assumes a significant role in the pathogenesis of osteoarthritis (OA). However, the current biomarkers for the diagnosis and treatment of OA are not satisfactory. Our study aims to identify new OA immune-related
Externí odkaz:
https://doaj.org/article/03b968bb8b5144b7b29fc1f48875d72e
Autor:
Xu Lin, Hong-Mei Xiao, Hui-Min Liu, Wan-Qiang Lv, Jonathan Greenbaum, Rui Gong, Qiang Zhang, Yuan-Cheng Chen, Cheng Peng, Xue-Juan Xu, Dao-Yan Pan, Zhi Chen, Zhang-Fang Li, Rou Zhou, Xia-Fang Wang, Jun-Min Lu, Zeng-Xin Ao, Yu-Qian Song, Yin-Hua Zhang, Kuan-Jui Su, Xiang-He Meng, Chang-Li Ge, Feng-Ye Lv, Zhe Luo, Xing-Ming Shi, Qi Zhao, Bo-Yi Guo, Neng-Jun Yi, Hui Shen, Christopher J. Papasian, Jie Shen, Hong-Wen Deng
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Although the gut microbiota has been reported to influence osteoporosis risk, the individual species involved, and underlying mechanisms, remain largely unknown. We performed integrative analyses in a Chinese cohort of peri-/post-menopausal
Externí odkaz:
https://doaj.org/article/b8089b80377041d18871e82953a90031
Publikováno v:
International Journal of Oral Science, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract The biomolecular mechanisms that regulate tooth root development and odontoblast differentiation are poorly understood. We found that Atp6i deficient mice (Atp6i −/− ) arrested tooth root formation, indicated by truncated Hertwig’s epi
Externí odkaz:
https://doaj.org/article/e3ea1eb5e24b4b01a0e9565183c1fde4
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionThe number of primordial follicles (PFs) in mammals determines the ovarian reserve, and impairment of primordial follicle formation (PFF) will cause premature ovarian insufficiency (POI).MethodsBy analyzing public single-cell RNA sequenci
Externí odkaz:
https://doaj.org/article/7230b2eb96504e9f84e1469054897bb9
Publikováno v:
Neuroimage: Reports, Vol 3, Iss 4, Pp 100191- (2023)
Most packages for the analysis of fMRI-based functional connectivity (FC) and genomic data are used with a programming language interface, lacking an easy-to-navigate GUI frontend. This exacerbates two problems found in these types of data: demograph
Externí odkaz:
https://doaj.org/article/d301d048a7874a4a8a809032ce884c54
Autor:
Chen Zhao, Joyce H. Keyak, Xuewei Cao, Qiuying Sha, Li Wu, Zhe Luo, Lan-Juan Zhao, Qing Tian, Michael Serou, Chuan Qiu, Kuan-Jui Su, Hui Shen, Hong-Wen Deng, Weihua Zhou
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundHip fracture occurs when an applied force exceeds the force that the proximal femur can support (the fracture load or “strength”) and can have devastating consequences with poor functional outcomes. Proximal femoral strengths for specif
Externí odkaz:
https://doaj.org/article/41f27814caf746efa6a4af37bfe51164