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Akademický článek

FTO Inhibits Insulin Secretion and Promotes NF-κB Activation through Positively Regulating ROS Production in Pancreatic β cells.

Autor: Hong-Qi Fan, Wei He, Kuan-Feng Xu, Zhi-Xiao Wang, Xin-Yu Xu, Heng Chen

Publikováno v: PLoS ONE, Vol 10, Iss 5, p e0127705 (2015)

FTO (Fat mass and obesity-associated) is associated with increased risk of obesity and type 2 diabetes incurrence. Pancreas islet β cells dysfunction and insulin resistance are major causes of type 2 diabetes. However, whether FTO plays an important

Externí odkaz: https://doaj.org/article/a634ca445b8046fbbadd3e87478f70a6

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Akademický článek

Association of serum uric acid with 2-hour postload glucose in Chinese with impaired fasting plasma glucose and/or HbA1c.

Autor: Hong-Qi Fan, Wei Tang, Zhi-Xiao Wang, Su-Juan Wang, Yue-Hua Qin, Qi Fu, Yuan Gao, Min Sun, Mei Zhang, Hong-Wen Zhou, Tao Yang

Publikováno v: PLoS ONE, Vol 8, Iss 7, p e67759 (2013)

ObjectiveTo examine whether serum uric acid (SUA) is associated with 2-hour postload glucose (2-h PG) in Chinese with impaired fasting plasma glucose (IFG) and/or HbA1c (IA1C).Research design and methodsAnthropometric and biochemical examinations, su

Externí odkaz: https://doaj.org/article/a27cac1a90354147a559903c1e34a2de

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Changes in levels of testosterone, insulin sensitivity and metabolic profiles during GnRH therapy: Reciprocity between insulin sensitivity and pituitary responsiveness to GnRH in teenage and young male patients with congenital hypogonadotropic hypogonadism

Autor: Hong‐Qi Fan, Yu‐Cheng Wang, Wei He, Hong‐Wen Zhou, Tao Yang

Publikováno v: Clinical endocrinologyREFERENCES. 97(6)

A direct evaluation of insulin sensitivity on pituitary response to gonadotropin relasing hormone (GnRH) has not been shown in congenital hypogonadotropic hypogonadism (CHH), despite a growing body of evidence in the association of testosterone conce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274c83f5d63612292984b165aacaa92a
https://pubmed.ncbi.nlm.nih.gov/36181235

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Peripheral and central augmentation indexes in relation to the CYP4F2 polymorphisms in Chinese

Autor: Yi Zhang, Hong-Qi Fan, Ji-Guang Wang, Chang-Sheng Sheng, Bang-Chuan Hu, Fa-Hong Li, Yan Li

Publikováno v: Journal of Hypertension. 29:501-508

Objective Cytochrome (CYP) 4F2 isoform is a key metabolizing enzyme for the renal 20-hydroxyeicosatetraenoic acid (20-HETE), which, as an endogenous vasoconstrictor, may influence properties of the peripheral muscular arteries and arterioles. We, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a783907933160613cfae9b5214d8e568
https://doi.org/10.1097/hjh.0b013e328342673c

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Prognostic value of isolated nocturnal hypertension on ambulatory measurement in 8711 individuals from 10 populations

Publikováno v: Journal of Hypertension, 28(10), 2036-2045. LIPPINCOTT WILLIAMS & WILKINS
Journal of Hypertension; Vol 28
Journal of Hypertension

BACKGROUND: We and other investigators previously reported that isolated nocturnal hypertension on ambulatory measurement (INH) clustered with cardiovascular risk factors and was associated with intermediate target organ damage. We investigated wheth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6534adb86cd8d9fb4347826ae511ae2b
https://doi.org/10.1097/hjh.0b013e32833b49fe

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Resistin induces insulin resistance, but does not affect glucose output in rat-derived hepatocytes

Autor: Jie Qiu, Hong-qi Fan, Feng Liu, Bin Wang, Tao Yang, Rong-hua Chen, Mei Guo, Nan Gu, Li Fei, Chun-Mei Zhang, Xiao-qing Pan, Xirong Guo, Min Zhang

Publikováno v: Acta Pharmacologica Sinica. 29:98-104

Aim: The aim of the present study was to observe the effects of resistin on insulin sensitivity and glucose output in rat-derived hepatocytes. Methods: The rat hepatoma cell line H4IIE was cultured and stimulated with resistin; supernant glucose and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f62db79f98b53c3728a2c7543cfb92d
https://doi.org/10.1111/j.1745-7254.2008.00709.x

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Prolonged exposure to resistin inhibits glucose uptake in rat skeletal muscles

Autor: Xirong Guo, Li Fei, Ronghua Chen, Mei Guo, Xiao-qin Pan, Nan Gu, Hong-qi Fan, Feng Liu

Publikováno v: Acta pharmacologica Sinica. 28(3)

Aim: To assess the effects and mechanisms of the action of resistin on basal and insulin-stimulated glucose uptake in rat skeletal muscle cells. Methods: Rat myo-blasts (L6) were cultured and differentiated into myotubes followed by stimulation with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a374993996b59e8e2040a775149830e0
https://pubmed.ncbi.nlm.nih.gov/17303005

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