Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Hong-Kiat Ng"'
Publikováno v:
Biology Direct, Vol 13, Iss 1, Pp 1-26 (2018)
Abstract Background Though earlier works on modelling transcript abundance from vertebrates to lower eukaroytes have specifically singled out the Zip’s law, the observed distributions often deviate from a single power-law slope. In hindsight, while
Externí odkaz:
https://doaj.org/article/8a8f12e57acf4714a1fcf42dd15e91c3
Autor:
Theresia Mina, Yik Weng Yew, Hong Kiat Ng, Nilanjana Sadhu, Gervais Wansaicheong, Rinkoo Dalan, Dorrain Yan Wen Low, Benjamin Chih Chiang Lam, Elio Riboli, Eng Sing Lee, Joanne Ngeow, Paul Elliott, Konstadina Griva, Marie Loh, Jimmy Lee, John Chambers
Publikováno v:
The Lancet Regional Health. Western Pacific, Vol 33, Iss , Pp 100710- (2023)
Summary: Background: Obesity and related metabolic disturbances including diabetes, hypertension and hyperlipidemia predict future cognitive decline. Asia has a high prevalence of both obesity and metabolic disease, potentially amplifying the future
Externí odkaz:
https://doaj.org/article/3e18564e800c4e7c8343b6997b4fc7b1
Identification of genetic effects underlying type 2 diabetes in South Asian and European populations
Autor:
Marie Loh, Weihua Zhang, Hong Kiat Ng, Katharina Schmid, Amel Lamri, Lin Tong, Meraj Ahmad, Jung-Jin Lee, Maggie C. Y. Ng, Lauren E. Petty, Cassandra N. Spracklen, Fumihiko Takeuchi, Md. Tariqul Islam, Farzana Jasmine, Anuradhani Kasturiratne, Muhammad Kibriya, Karen L. Mohlke, Guillaume Paré, Gauri Prasad, Mohammad Shahriar, Miao Ling Chee, H. Janaka de Silva, James C. Engert, Hertzel C. Gerstein, K. Radha Mani, Charumathi Sabanayagam, Marijana Vujkovic, Ananda R. Wickremasinghe, Tien Yin Wong, Chittaranjan S. Yajnik, Salim Yusuf, Habibul Ahsan, Dwaipayan Bharadwaj, Sonia S. Anand, Jennifer E. Below, Michael Boehnke, Donald W. Bowden, Giriraj R. Chandak, Ching-Yu Cheng, Norihiro Kato, Anubha Mahajan, Xueling Sim, Mark I. McCarthy, Andrew P. Morris, Jaspal S. Kooner, Danish Saleheen, John C. Chambers
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Marie Loh, Weihua Zhang et al. use a genome-wide association study meta-analysis to examine variants associated with Type 2 diabetes (T2D) in South Asian and European ancestry cohorts. Their results provide further insights into the genetic mechanism
Externí odkaz:
https://doaj.org/article/07ab4de945a54b4f8a1b8fb3e19f5d29
Autor:
Theresia Mina, Yik Weng Yew, Hong Kiat Ng, Nilanjana Sadhu, Gervais Wansaicheong, Rinkoo Dalan, Dorrain Yan Wen Low, Benjamin Chih Chiang Lam, Elio Riboli, Eng Sing Lee, Joanne Ngeow, Paul Elliott, Konstadina Griva, Marie Loh, Jimmy Lee, John Chambers
Background: Obesity and related metabolic disturbances including diabetes, hypertension and hyperlipidemia predict future cognitive decline. Asia has a high prevalence of both obesity and metabolic disease, potentially amplifying the future burden of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f330f0c6ab9c5ee252618ffdb11ce911
https://hdl.handle.net/10356/165808
https://hdl.handle.net/10356/165808
Autor:
Marie Loh, Weihua Zhang, Hong Kiat Ng, Katharina Schmid, Amel Lamri, Lin Tong, Meraj Ahmad, Jung-Jin Lee, Maggie C. Y. Ng, Lauren E. Petty, Cassandra N. Spracklen, Fumihiko Takeuchi, Md. Tariqul Islam, Farzana Jasmine, Anuradhani Kasturiratne, Muhammad Kibriya, Karen L. Mohlke, Guillaume Paré, Gauri Prasad, Mohammad Shahriar, Miao Ling Chee, H. Janaka de Silva, James C. Engert, Hertzel C. Gerstein, K. Radha Mani, Charumathi Sabanayagam, Marijana Vujkovic, Ananda R. Wickremasinghe, Tien Yin Wong, Chittaranjan S. Yajnik, Salim Yusuf, Habibul Ahsan, Dwaipayan Bharadwaj, Sonia S. Anand, Jennifer E. Below, Michael Boehnke, Donald W. Bowden, Giriraj R. Chandak, Ching-Yu Cheng, Norihiro Kato, Anubha Mahajan, Xueling Sim, Mark I. McCarthy, Andrew P. Morris, Jaspal S. Kooner, Danish Saleheen, John C. Chambers
Publikováno v:
Communications Biology. 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4b84c2d2a2713087fcad4cd9be8265c
https://doi.org/10.1038/s42003-022-03404-x
https://doi.org/10.1038/s42003-022-03404-x
Publikováno v:
Molecular Metabolism, Vol 27, Iss, Pp S33-S41 (2019)
Molecular Metabolism
Molecular Metabolism
Background Obesity and type 2 diabetes (T2D) are major public health issues worldwide, and put a significant burden on the healthcare system. Genetic variants, along with traditional risk factors such as diet and physical activity, could account for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a0de3d49a9b993f8e59584a25f5aa7
https://doi.org/10.1016/j.molmet.2019.06.011
https://doi.org/10.1016/j.molmet.2019.06.011
Autor:
Li Zhou, Hong Kiat Ng, Daniela I. Drautz-Moses, Stephan C. Schuster, Stephan Beck, Changhoon Kim, John Campbell Chambers, Marie Loh
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Whole genome bisulfite sequencing (WGBS), with its ability to interrogate methylation status at single CpG site resolution epigenome-wide, is a powerful technique for use in molecular experiments. Here, we aim to advance strategies for accurate and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e03fdac17a8f586da53da73e663b6747
http://hdl.handle.net/10220/49792
http://hdl.handle.net/10220/49792
Publikováno v:
Biology Direct, Vol 13, Iss 1, Pp 1-26 (2018)
Biology Direct
Biology Direct
Background Though earlier works on modelling transcript abundance from vertebrates to lower eukaroytes have specifically singled out the Zip’s law, the observed distributions often deviate from a single power-law slope. In hindsight, while power-la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e12279b6ae495ce23b966fbb0caba49
https://doi.org/10.1186/s13062-018-0204-y
https://doi.org/10.1186/s13062-018-0204-y
Significant transcripts calls of comparative dilution analysis (AGS versus NUGC3) before and after power-law correction. (DOCX 16 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cd9bff888240b51343b62f614624e76
Table S2. Significant transcripts calls of comparative dilution analysis (AGS versus NUGC3) before and after power-law correction. (DOCX 16 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331a16f99453212690211f42477cf791