Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Hong-Jun Lee"'
Autor:
Sung Woo Lee, Soyoon Kim, Bokyung Kim, Jung Bae Seong, Young-Ho Park, Hong Jun Lee, Dong Kyu Choi, Eunbyul Yeom, Dong-Seok Lee
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-17 (2024)
Abstract Background Targeting the tumor microenvironment represents an emerging therapeutic strategy for cancer. Macrophages are an essential part of the tumor microenvironment. Macrophage polarization is modulated by mitochondrial metabolism, includ
Externí odkaz:
https://doaj.org/article/8225297662494e4fb3f25c4ffcc9baeb
Publikováno v:
Korean Journal of Pediatrics, Vol 59, Iss Suppl 1, Pp S116-S120 (2016)
Congenital hyperinsulinism (CHI) is a rare condition that can cause irreversible brain damage during the neonatal period owing to the associated hypoglycemia. Hypoglycemia in CHI occurs secondary to the dysregulation of insulin secretion. CHI has bee
Externí odkaz:
https://doaj.org/article/031e6de77a064c8d8d8bc7a7c1a261c8
Publikováno v:
International Neurourology Journal, Vol 27, Iss 4, Pp 271-279 (2023)
Purpose Ischemia of the bladder can occur if neovascular formation cannot keep pace with hypoxia induced by chronic bladder outlet obstruction (BOO). The aim of this study was to examine changes in angiogenesis growth factor expression generated by c
Externí odkaz:
https://doaj.org/article/8f12f25a98ee411b8a3ffc9c21ace23f
Publikováno v:
International Neurourology Journal, Vol 27, Iss 4, Pp 234-242 (2023)
Purpose Men with diabetes mellitus (DM) often present with severe erectile dysfunction (ED). This ED is less responsive to current pharmacological therapies. If we know the upregulated or downregulated genes of diabetic ED, we can inhibit or enhance
Externí odkaz:
https://doaj.org/article/aa891271d3a042279636da29d80f169f
Autor:
Hong Jun Lee, Jae Seung Lee, Hyesung So, Ja Kyung Yoon, Jin-Young Choi, Hye Won Lee, Beom Kyung Kim, Seung Up Kim, Jun Yong Park, Sang Hoon Ahn, Do Young Kim
Publikováno v:
Yonsei Medical Journal; Jul2024, Vol. 65 Issue 7, p371-379, 9p
Publikováno v:
Redox Report, Vol 26, Iss 1, Pp 53-61 (2021)
Objectives: Although glutamate is an essential factor in the neuronal system, excess glutamate can produce excitotoxicity. We previously reported that Peroxiredoxin 5 (Prx5) protects neuronal cells from glutamate toxicity via its antioxidant effects.
Externí odkaz:
https://doaj.org/article/acd1aa8712b748aba6a93a102762b2e6
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 1889 (2022)
In Alzheimer’s disease, reactive oxygen species (ROS) are generated by the deposition of amyloid-beta oligomers (AβOs), which represent one of the important causes of neuronal cell death. Additionally, AβOs are known to induce autophagy via ROS i
Externí odkaz:
https://doaj.org/article/97e981e075944fd1a71def3ff2c89c36
Autor:
Jung Yeon Lim, Jung Eun Lee, Soon A Park, Sang In Park, Jung-Min Yon, Jeong-Ah Park, Sin-Soo Jeun, Seung Joon Kim, Hong Jun Lee, Sung Won Kim, Seung Ho Yang
Publikováno v:
Cells, Vol 11, Iss 6, p 1029 (2022)
The aim of this study was to validate the use of human brain organoids (hBOs) to investigate the therapeutic potential and mechanism of human-neural-crest-derived nasal turbinate stem cells (hNTSCs) in models of Alzheimer’s disease (AD). We generat
Externí odkaz:
https://doaj.org/article/a6707528855a42919f737ff89a98fe1a
Publikováno v:
International Journal of Control, Automation and Systems. 21:1233-1242
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::016de5c2d4dbe26656c8bb7da5273a2f
https://doi.org/10.1007/s12555-021-1033-9
https://doi.org/10.1007/s12555-021-1033-9
Autor:
Lusine Danielyan, Matthias Schwab, Georg Siegel, Bianca Brawek, Olga Garaschuk, Nithi Asavapanumas, Marine Buadze, Ali Lourhmati, Hans-Peter Wendel, Meltem Avci-Adali, Marcel A. Krueger, Carsten Calaminus, Ulrike Naumann, Stefan Winter, Elke Schaeffeler, Annett Spogis, Sandra Beer-Hammer, Jonas J. Neher, Gabriele Spohn, Anja Kretschmer, Eva-Maria Krämer-Albers, Kerstin Barth, Hong Jun Lee, Seung U. Kim, William H. Frey, II, Claus D. Claussen, Dirk M. Hermann, Thorsten R. Doeppner, Erhard Seifried, Christoph H. Gleiter, Hinnak Northoff, Richard Schäfer
Publikováno v:
EBioMedicine, Vol 60, Iss , Pp 102989- (2020)
Background: Stem cells` (SC) functional heterogeneity and its poorly understood aetiology impedes clinical development of cell-based therapies in regenerative medicine and oncology. Recent studies suggest a strong correlation between the SC migration
Externí odkaz:
https://doaj.org/article/50fadaeaeb26482dbe9ab2d00b7b2fef