Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Hong-Jie Qian"'
Autor:
Yu-zhou Gui, Wei Wang, Qing-qing Wu, Qi-chen Ding, Hong-jie Qian, Qiu-bei Lu, Ying-jun Zhang, Yu-lei Zhuang, Li Deng, Ying-lin Zuo, Lin Luo, Jing-ying Jia
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Heart failure is the most costly cardiovascular disorder. New treatments are urgently needed. This study aims to evaluate the safety, pharmacokinetics, and pharmacodynamic profile of HEC95468, a soluble guanylate cyclase (sGC) stimulator, in healthy
Externí odkaz:
https://doaj.org/article/471eb2450690481191e91200a2f0c4db
Autor:
Hong-Yan Zhou, Hua Sui, Yang-Jianing Zhao, Hong-Jie Qian, Nan Yang, Lu Liu, Qing Guan, Yue Zhou, Hong-Li Lin, Da-Peng Wang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Inflammation is a type of defense response against tissue damage, and can be mediated by lymphocytes and macrophages. Fibrosis is induced by tissue injury and inflammation, which leads to an increase in fibrous connective tissue in organs and a decre
Externí odkaz:
https://doaj.org/article/839b9533475445758f17cdafa2090eeb
Autor:
Hong-Jie, Qian, Yu, Wang, Meng-Qi, Zhang, Yuan-Chao, Xie, Qing-Qing, Wu, Li-Yu, Liang, Ye, Cao, Hua-Qing, Duan, Guang-Hui, Tian, Juan, Ma, Zhuo-Bing, Zhang, Ning, Li, Jing-Ying, Jia, Jing, Zhang, Haji Akber, Aisa, Jing-Shan, Shen, Chen, Yu, Hua-Liang, Jiang, Wen-Hong, Zhang, Zhen, Wang, Gang-Yi, Liu
Publikováno v:
Acta Pharmacologica Sinica. 43:3130-3138
VV116 (JT001) is an oral drug candidate of nucleoside analog against SARS-CoV-2. The purpose of the three phase I studies was to evaluate the safety, tolerability, and pharmacokinetics of single and multiple ascending oral doses of VV116 in healthy s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f77db18606a2fac97fa1e043e75236f
https://doi.org/10.1038/s41401-022-00895-6
https://doi.org/10.1038/s41401-022-00895-6
Autor:
Chen Yu, Wei Wang, Dong-ying Lu, Meng-qi Zhang, Yun Liu, Fu Zhu, Liang Xin, Hong-jie Qian, Yiping Wang, Jie-mei Jin, Hongchao Zheng, Gangyi Liu, Jingying Jia
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 42:593-599
Sulcardine sulfate is a novel antiarrhythmic agent with mechanism of action as a multi-ion channel blocker. Preclinical studies in animal models have demonstrated that sulcardine sulfate is efficacious in atrial and ventricular arrhythmias, and conse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b3597dabfeefd6c4e3f0da2c81c078
https://doi.org/10.1007/s13318-016-0370-1
https://doi.org/10.1007/s13318-016-0370-1