Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Hong-Jen Lee"'
Autor:
Hong-Jen Lee, Chien-Feng Li, Diane Ruan, Jiabei He, Emily D. Montal, Sonja Lorenz, Geoffrey D. Girnun, Chia-Hsin Chan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Cancer cells develop specific metabolic adaptations. Here, the authors show that in prostate cancer models, the ubiquitin ligase Hect9 promotes tumor growth by accelerating glucose metabolism via ubiquitination of Hexokinase 2, a central regulator of
Externí odkaz:
https://doaj.org/article/c1e48419d9bc4725802932966b49bd52
Publikováno v:
Molecular & Cellular Oncology, Vol 6, Iss 5 (2019)
Our study uncovered that HectH9 drives glycolysis and tumor development by K63-linked ubiquitination of Hexokinase 2 (HK2). This mechanism is critical for HK2 localization to mitochondria for activating HK2’s functions in glycolysis promotion and a
Externí odkaz:
https://doaj.org/article/c9d61ab415f44592a6666405a41b3488
Autor:
Hong-Jen Lee, 李宏仁
96
Active control technology is applied on the vibration suppression of a micron positioning stage. The frequency range of vibration to control is 0~40Hz(especially lower than 10Hz), and the amplitude is lower than 20um(peak value). Th
Active control technology is applied on the vibration suppression of a micron positioning stage. The frequency range of vibration to control is 0~40Hz(especially lower than 10Hz), and the amplitude is lower than 20um(peak value). Th
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/wa4sm5
Autor:
Hong-Jen Lee, 李宏仁
92
PartI:Abstract Ricin, consists of A chain (RTA) and B chain (RTB), is a toxic protein which was isolated from the seeds of the castor beans Ricinus communis. It is a member of type Ⅱ ribosome-inactivating protein (RIP). The RTA possesses
PartI:Abstract Ricin, consists of A chain (RTA) and B chain (RTB), is a toxic protein which was isolated from the seeds of the castor beans Ricinus communis. It is a member of type Ⅱ ribosome-inactivating protein (RIP). The RTA possesses
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/03227554177038464641
Autor:
Hong-Jen Lee
Thesis (M.A.)--National Taiwan University Graduate Institute of Biochemistry and Molecularbiology
Includes bibliographical references
Includes bibliographical references
Autor:
Mien-Chie Hung, Gabriel N. Hortobagyi, Edward T.H. Yeh, Yan Wang, Hui-Lung Sun, Chia-Jui Yen, Jennifer L. Hsu, Wen-Hsuan Yu, Weiya Xia, Heng-Huan Lee, Yi Du, Hong-Jen Lee, Hirohito Yamaguchi, Chun-Te Chen
Several antiangiogenic drugs targeting VEGF/VEGF receptor (VEGFR) that were approved by the Food and Drug Administration for many cancer types, including colorectal and lung cancer, can effectively reduce tumor growth. However, targeting the VEGF sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f68c6b6cfc056a298ee311664f806ba7
https://doi.org/10.1158/1535-7163.c.6535329
https://doi.org/10.1158/1535-7163.c.6535329
Autor:
Mien-Chie Hung, Gabriel N. Hortobagyi, Edward T.H. Yeh, Yan Wang, Hui-Lung Sun, Chia-Jui Yen, Jennifer L. Hsu, Wen-Hsuan Yu, Weiya Xia, Heng-Huan Lee, Yi Du, Hong-Jen Lee, Hirohito Yamaguchi, Chun-Te Chen
Supplementary Figures 1-4 from Dual Targeting of Tumor Angiogenesis and Chemotherapy by Endostatin–Cytosine Deaminase–Uracil Phosphoribosyltransferase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::521110bb67c27c15c1827288f0fb525c
https://doi.org/10.1158/1535-7163.22496592.v1
https://doi.org/10.1158/1535-7163.22496592.v1
Autor:
Mien-Chie Hung, Gabriel N. Hortobagyi, Edward T.H. Yeh, Yan Wang, Hui-Lung Sun, Chia-Jui Yen, Jennifer L. Hsu, Wen-Hsuan Yu, Weiya Xia, Heng-Huan Lee, Yi Du, Hong-Jen Lee, Hirohito Yamaguchi, Chun-Te Chen
Supplementary Methods from Dual Targeting of Tumor Angiogenesis and Chemotherapy by Endostatin–Cytosine Deaminase–Uracil Phosphoribosyltransferase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b74c342730440d62080b5119a777b3
https://doi.org/10.1158/1535-7163.22496589.v1
https://doi.org/10.1158/1535-7163.22496589.v1
Publikováno v:
The FASEB Journal. 35
Publikováno v:
2020 China Semiconductor Technology International Conference (CSTIC).
Hotspots often lead to unexpected critical dimension (CD) behavior, degradation of process window and ultimately impact wafer yield. The most important aspects of the patterning process in device manufacturing are to calibrate the OPC model, correct