Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Hong-Guang Nie"'
Publikováno v:
Cellular Physiology and Biochemistry, Vol 44, Iss 3, Pp 1120-1132 (2017)
Epithelial sodium channels (ENaC) play an important role in re-absorbing excessive luminal fluid by building up an osmotic Na+ gradient across the tight epithelium in the airway, the lung, the kidney, and the colon. The ENaC is a major pathway for re
Externí odkaz:
https://doaj.org/article/7efdad14e4bc4b4eb4563ef29495e984
Autor:
Cong Liu, Yana Ma, Zhenlei Su, Runzhen Zhao, Xiaoli Zhao, Hong-Guang Nie, Ping Xu, Lili Zhu, Mo Zhang, Xiumin Li, Xiaoju Zhang, Michael A. Matthay, Hong-Long Ji
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
BackgroundAcute lung injury (ALI) is characterized by suppressed fibrinolytic activity in bronchoalveolar lavage fluid (BALF) attributed to elevated plasminogen activator inhibitor-1 (PAI-1). Restoring pulmonary fibrinolysis by delivering tissue-type
Externí odkaz:
https://doaj.org/article/8caac9b5e7c243bbabc4774b4bc5cb01
Autor:
Michael A. Matthay, Deepa Bhattarai, Hong-Long Ji, Yongchang Chang, Gibran Ali, Hong-Guang Nie, Xiaoli Zhao, Runzhen Zhao, Xuefeng Su
Background and PurposeLung oedema in association with suppressed fibrinolysis is a hallmark of lung injury. We aimed to test whether plasmin cleaves epithelial sodium channels (ENaC) to resolve lung oedema fluid.Experimental ApproachesHuman lungs and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b4e36ce92568c1befb093f0b98af253
https://doi.org/10.1101/2020.02.09.940619
https://doi.org/10.1101/2020.02.09.940619
Publikováno v:
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Cellular Physiology and Biochemistry, Vol 44, Iss 3, Pp 1120-1132 (2017)
Cellular Physiology and Biochemistry, Vol 44, Iss 3, Pp 1120-1132 (2017)
Epithelial sodium channels (ENaC) play an important role in re-absorbing excessive luminal fluid by building up an osmotic Na+ gradient across the tight epithelium in the airway, the lung, the kidney, and the colon. The ENaC is a major pathway for re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2859e3f9e413cf1125ca8ef4b3bd7616
https://doi.org/10.1159/000485417
https://doi.org/10.1159/000485417
Publikováno v:
The Journal of Membrane Biology. 248:197-204
Ion channel expression and activity may be affected during tumor development and cancer growth. Activation of potassium (K(+)) channels in human breast cancer cells is reported to be involved in cell cycle progression. In this study, we investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b93ce834c7a6848b14251d905b5168
https://doi.org/10.1007/s00232-014-9757-6
https://doi.org/10.1007/s00232-014-9757-6
Autor:
Dong-Yun Han1, Hong-Guang Nie1,2, Xiu Gu1,3, Nayak, Ramesh C.1, Xue-Feng Su1, Jian Fu1, Yongchang Chang4, Rao, Vijay1, Hong-Long Ji1,5 james.ji@uthct.edu
Publikováno v:
Respiratory Research. 2010, Vol. 11, p65-81. 17p.
Autor:
Run Zhen Zhao, Andrew Lee, Yao Huang, Xue Feng Su, Yongchang Chang, Sadis Matalon, Hong Guang Nie, Hong Long Ji, Dong Yun Han
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology
Salt absorption via apical epithelial sodium channels (ENaC) is a critical rate-limiting process in maintaining airway and lung lining fluid at the physiological level. δ ENaC (termed δ1 in this article) has been detected in human lung epithelial c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f1299bc31581c262f4a13a3eba09ad
https://doi.org/10.1152/ajplung.00331.2011
https://doi.org/10.1152/ajplung.00331.2011
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 3, p 881 (2018)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Transepithelial fluid and salt re-absorption in epithelial tissues play an important role in fluid and salt homeostasis. In absorptive epithelium, fluid and salt flux is controlled by machinery mainly composed of epithelial sodium channels (ENaC), cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36e47ba5deaab7f8ba703369ba6d8e7
https://doi.org/10.3390/ijms19030881
https://doi.org/10.3390/ijms19030881
Autor:
Xiu Gu, Weifeng Song, Xiao Hui Fang, Sadis Matalon, Shipeng Wei, Lan Chen, Hong Long Ji, Dong Yun Han, Jun Li, Hong Guang Nie
Publikováno v:
The Journal of Physiology. 587:2663-2676
Airway and alveolar fluid clearance is mainly governed by vectorial salt movement via apically located rate-limiting Na+ channels (ENaC) and basolateral Na+/K+-ATPases. ENaC is regulated by a spectrum of protein kinases, i.e. protein kinase A (PKA),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfa94512f6c59faaafb9045afd78d2a9
https://doi.org/10.1113/jphysiol.2009.170324
https://doi.org/10.1113/jphysiol.2009.170324
SARS-CoV proteins decrease levels and activity of human ENaC via activation of distinct PKC isoforms
Autor:
Weifeng Song, Sadis Matalon, Yong Jian Zhou, Hong Guang Nie, Xue Feng Su, Zhiqian Gao, Hong Long Ji, Albert Tousson, Yu Xian He, Ji-Bin Peng, Ying Liao, Yi Jiang
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology
Among the multiple organ disorders caused by the severe acute respiratory syndrome coronavirus (SARS-CoV), acute lung failure following atypical pneumonia is the most serious and often fatal event. We hypothesized that two of the hydrophilic structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c80a4432dac29ad9620946744a0515c8