Neural computational modeling reveals a major role of corticospinal gating of central oscillations in the generation of essential tremor

Autor: Hong-en Qu, Chuanxin M Niu, Si Li, Man-zhao Hao, Zi-xiang Hu, Qing Xie, Ning Lan

Publikováno v: Neural Regeneration Research, Vol 12, Iss 12, Pp 2035-2044 (2017)

Essential tremor, also referred to as familial tremor, is an autosomal dominant genetic disease and the most common movement disorder. It typically involves a postural and motor tremor of the hands, head or other part of the body. Essential tremor is

Externí odkaz: https://doaj.org/article/33cbe911125b4f1a92db83f06210b771

RuCl3·3H2O Catalyzed Reactions: Facile Synthesis of Bis(indolyl)methanes under Mild Conditions

Autor: Liang-Xian Liu, Qiao-Sheng Hu, Kai-Hui Yu, Ning Wang, Chen Xiao, Hong-En Qu

Publikováno v: Molecules, Vol 16, Iss 5, Pp 3855-3868 (2011)

RuCl3·3H2O was found to be an effective catalyst for reactions of indoles, 2-methylthiophene, and 2-methylfuran with aldehydes to afford the corresponding bis(indolyl)methanes, bis(thienyl)methanes, and bis(fur-2-yl)methanes in moderate to excellent

Externí odkaz: https://doaj.org/article/9a5c490885d443718b62cb6341193117

Regioselective Synthesis of β-Aryl Enaminones and 1,4,5- Trisubstituted 1,2,3-Triazoles from Chalcones and Benzyl Azides

Autor: Hong-En Qu, Xian-chun Tan, Ying-Chun Wang, Heng-Shan Wang, Yu-Yang Xie, Ying-Ming Pan

Publikováno v: Advanced Synthesis & Catalysis. 356:3347-3355

Depending on the solvent used, the efficient synthesis of either β-aryl enaminones (DMF) or 1,4,5-trisubstituted 1,2,3-triazoles (toluene) succeeds in a highly regioselective manner.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd9981edea2d32c0537feb0ce1d786df
https://doi.org/10.1002/adsc.201400315

Synthesis of Ethyl Isoxazole-3-Carboxylates Using an Ionic Liquid as a Soluble Support

Autor: Shou-Ri Sheng, Mingzhong Cai, Qiao-Sheng Hu, Wusheng Sheng, Hong-En Qu

Publikováno v: Journal of Heterocyclic Chemistry. 51:315-321

A regioselective 1,3-dipolar cycloadditions of ionic liquid-supported vinyl ethers, derived from ionic liquid-supported α-phenylselenomethyl ether, with ethyl cyanoformate N-oxide gave supported isoxazoline derivatives, which were then cleaved from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::96ba859a4f9ce40a28c4f7e506e385e5
https://doi.org/10.1002/jhet.1673

Synthesis and Biological Evaluation of Novel Dehydroabietic Acid Derivatives Conjugated with Acyl-Thiourea Peptide Moiety as Antitumor Agents

Autor: Ying-Ming Pan, Dong Liang, Le Jin, Hong-En Qu, Xiaochao Huang, Ye Zhang, Zhen-Feng Chen, Heng-Shan Wang

Publikováno v: International Journal of Molecular Sciences
Volume 16
Issue 7
Pages 14571-14593
International Journal of Molecular Sciences, Vol 16, Iss 7, Pp 14571-14593 (2015)

A series of dehydroabietic acid (DHAA) acyl-thiourea derivatives were designed and synthesized as potent antitumor agents. The in vitro pharmacological screening results revealed that the target compounds exhibited potent cytotoxicity against HeLa, S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e69f87ca5d8850b6130ec16b0a77320