Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Hong-Di Ma"'
Autor:
Shu-Han Yang, Liang Li, Yu-Qing Xie, Yuan Yao, Cai-Yue Gao, Liang-Huan Liao, Hong-Di Ma, M. Eric Gershwin, Zhe-Xiong Lian
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Autoimmune diseases often induce dysregulated hematopoiesis with altered number and function of hematopoietic stem and progenitor cells (HSPCs). However, there are limited studies on the direct regulation of HSPCs on T cells, which are often detrimen
Externí odkaz:
https://doaj.org/article/be8c31ee0a534850b9aa48ab6e23b14b
Autor:
Zhe-Xiong Lian, William M. Ridgway, M. Eric Gershwin, Zhigang Tian, Zhi-Bin Zhao, Wei Yang, Hong Di Ma, Weici Zhang, Fang Ting Lu, Yin Hu Wang, Jie Long, Jie Cao, Qi Miao
Publikováno v:
Cellular & molecular immunology, vol 17, iss 2
Cell Mol Immunol
Cell Mol Immunol
Liver-resident NK cells are distinct from conventional NK cells and play an important role in the maintenance of liver homeostasis. How liver-resident NK cells participate in autoimmune cholangitis remains unclear. Here, we extensively investigated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64ab595a4b2a04d20658c3702e9b9d33
https://escholarship.org/uc/item/8p61g60m
https://escholarship.org/uc/item/8p61g60m
Autor:
Bin Liu, Koichi Tsuneyama, Yongjian Zhou, Jinjun Wang, Wen Tao Ma, M. Eric Gershwin, Liang Li, Zhi-Bin Zhao, Cai Yue Gao, Zhe-Xiong Lian, Hong Di Ma, Weici Zhang, Qing Zhi Liu
Publikováno v:
Journal of Autoimmunity. 95:47-57
Gut microbiota and bacterial translocation have been implicated as significant contributors to mucosal immune responses and tolerance; alteration of microbial molecules, termed pathogen-associated molecular patterns (PAMP) and bacterial translocation
Autor:
Fang Ting Lu, Wei Yang, Yin Hu Wang, Zhi-Bin Zhao, Hong Di Ma, Zhe-Xiong Lian, William M. Ridgway, M. Eric Gershwin, Jing Bo Yang, Wei Tang, Koichi Tsuneyama, Yan Jie Jia
Publikováno v:
Journal of Autoimmunity. 66:108-117
There is a significant unmet need in the treatment of primary biliary cirrhosis (PBC) despite significant data on the effector pathways that lead to biliary duct damage. We focused attention on a murine model of PBC, the dominant negative transformin
Publikováno v:
Clinical Reviews in Allergy & Immunology. 50:390-403
Primary biliary cirrhosis (PBC) is a chronic inflammatory autoimmune disease that develops based upon the interaction of genetic and environmental factors. Recent genome-wide association studies (GWAS) have identified dozens of predisposing variants
Autor:
Qing Zhi Liu, Hong Di Ma, Yan Qing Yang, M. Eric Gershwin, Wen Tao Ma, Zhe-Xiong Lian, Zhi-Bin Zhao, Jing Bo Yang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Scientific Reports
Primary biliary cholangitis (PBC) is an autoimmune liver disease characterized by the destruction of interlobular biliary ductules, which progressively leads to cholestasis, hepatic fibrosis, cirrhosis, and eventually liver failure. Several mouse mod
Autor:
Wei Yang, Yuan Yao, Koichi Tsuneyama, Scott L. Friedman, Yan Yan Tao, Liang Li, Hong Di Ma, Weici Zhang, Fang Ting Lu, Yan Qing Yang, Zhe-Xiong Lian, M. Eric Gershwin
Publikováno v:
Journal of Autoimmunity. 51:99-108
The IL-12 family modulates T cell mediated autoimmune diseases and GWAS in PBC have suggested a critical role of IL-12 and its subunits in modulating portal inflammation. We have taken advantage of an aggressive model of portal inflammation and colit
Autor:
Fang Ting Lu, Xiao-Song He, M. Eric Gershwin, Wei Yang, Yan Ru Deng, Hong Di Ma, Koichi Tsuneyama, Yin Hu Wang, Anna Mae Diehl, Cheng Hai Liu, Ping Liu, Zhe-Xiong Lian
Publikováno v:
Journal of Autoimmunity. 46:25-34
There have been major advances in defining the immunological events associated with fibrosis in various chronic liver diseases. We have taken advantage of this data to focus on the mechanisms of action of a unique multi-kinase inhibitor, coined soraf
Autor:
Koichi Tsuneyama, William M. Ridgway, M. Eric Gershwin, Zhe-Xiong Lian, Wen Tao Ma, Aftab A. Ansari, Zhi-Bin Zhao, Hong Di Ma, Mu Zi Ying Liu, Yun Yun Fei, Qing Zhi Liu, Jin Ming Gao
CXC Chemokine Receptor 3 (CXCR3) is functionally pleiotropic and not only plays an important role in chemotaxis, but also participates in T cell differentiation and may play a critical role in inducing and maintaining immune tolerance. These observat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f82936f8b578f5071432bff1d766a8
https://europepmc.org/articles/PMC5357510/
https://europepmc.org/articles/PMC5357510/
Autor:
Zhenye Yang, Zhi-Bin Zhao, Yan Jie Jia, M. Eric Gershwin, Wen Tao Ma, Hong Di Ma, Zhe-Xiong Lian, Qing Zhi Liu, Jing Bo Yang, Qinghua Shi, Yan Qing Yang
Publikováno v:
Cell Death & Disease
Molecular mechanisms that modulate liver regeneration are of critical importance for a number of hepatic disorders. Kupffer cells and natural killer (NK) cells are two cell subsets indispensable for liver regeneration. We have focused on these two po