High expression of Ku70 promotes proliferation of ovarian cancer cell lines and is associated with a poor prognosis for patients

Autor: WANG Juan, ZHANG Xiao-yan, ZHU Ai-hua, YU Hong-bo, FAN Xin-dan, TANG Chun-hui, YAO Xiu-fang

Publikováno v: Jichu yixue yu linchuang, Vol 42, Iss 9, Pp 1391-1399 (2022)

Objective To investigate the expression of X-ray-repaired cross complementary protein 6 (Ku70/XRCC6) in epithelial ovarian cancer(EOC) and its effects on the proliferation, apoptosis and migration of ovarian cancer cells. Methods Western blot was use

Externí odkaz: https://doaj.org/article/550b1fc52dd94ca1a27f2432315e0967

Enhanced tensile properties and wear resistance of additively manufactured CoCrFeMnNi high-entropy alloy at cryogenic temperature

Autor: Hong-Ge Li, Peng-Cheng Che, Xiao-Kun Yang, Yong-Jiang Huang, Zhi-Liang Ning, Jian-Fei Sun, Hong-Bo Fan

Publikováno v: Rare Metals. 41:1210-1216

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::53751590e9b5fdd498021888e0596c8f
https://doi.org/10.1007/s12598-021-01867-1

Cordyceps militaris Immunomodulatory Protein Promotes the Phagocytic Ability of Macrophages through the TLR4-NF-κB Pathway

Autor: Hong-Bo Fan, Jun-Fang Lin, Qianwang Zheng, Li-Qiong Guo, Qing Han, Yuan Zou, Yingli Liu

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 12188, p 12188 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 22

Enhancing the phagocytosis of immune cells with medicines provides benefits to the physiological balance by removing foreign pathogens and apoptotic cells. The fungal immunomodulatory protein (FIP) possessing various immunopotentiation functions may

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f187d403d9e6cb4a0cfb03473651ec04
https://www.mdpi.com/1422-0067/22/22/12188

CDX2 Stimulates the Proliferation of Porcine Intestinal Epithelial Cells by Activating the mTORC1 and Wnt/β -Catenin Signaling Pathways.

Autor: Hong-Bo Fan¹ fanhb@stu.scau.edu.cn, Zhen-Ya Zhai¹ zhai@stu.scau.edu.cn, Xiang-Guang Li¹ li.7924@osu.edu, Chun-Qi Gao¹ cqgao@scau.edu.cn, Hui-Chao Yan¹ yanhc@scau.edu.cn, Zhe-Sheng Chen² chenz@stjohns.edu, Xiu-Qi Wang¹ xqwang@scau.edu.cn

Publikováno v: International Journal of Molecular Sciences. Nov2017, Vol. 18 Issue 11, p2447. 13p.

Acute exposure to deoxynivalenol inhibits porcine enteroid activity via suppression of the Wnt/β-catenin pathway

Autor: Zhenya Zhai, Xiu-Qi Wang, Chen Mingxia, Chun-Qi Gao, Xiang-guang Li, Hui-Chao Yan, Hou-Long Fu, Min Zhu, Hong-Bo Fan, Jia-Yi Zhou

Publikováno v: Toxicology letters. 305

The intake of food containing deoxynivalenol frequently causes damage to the intestine, the renewal of which is driven by intestinal stem cells (ISCs). Nevertheless, the toxicity of deoxynivalenol on ISCs and its underlying mechanisms remain to be el

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2df0c21689935165404a033a71a49259
https://pubmed.ncbi.nlm.nih.gov/30690062