Zobrazeno 1 - 10
of 389
pro vyhledávání: '"Hong Yan Lin"'
Autor:
Ya Ya Cao, Yuan Yuan Chen, Ming Shu Wang, Jing Jing Tong, Meng Xu, Chi Zhao, Hong Yan Lin, Long Can Mei, Jin Dong, Wen Lin Zhang, Yu Xuan Qin, Wei Huang, Dan Zhang, Guang Fu Yang
Publikováno v:
Redox Biology, Vol 63, Iss , Pp 102751- (2023)
Catalase (CAT) is an important antioxidant enzyme that breaks down H2O2 into water and oxygen. Inhibitor-modulating CAT activity in cancer cells is emerging as a potential anticancer strategy. However, the discovery of CAT inhibitors towards the heme
Externí odkaz:
https://doaj.org/article/b74183b4f2e34846a1c79c4a32702af6
Publikováno v:
Advanced Agrochem, Vol 2, Iss 2, Pp 163-172 (2023)
4-Hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, HPPD) is currently one of the popular targets of herbicide research, and herbicides targeting it have shown promising results in treating resistant weeds. However, the long-term application of HPPD
Externí odkaz:
https://doaj.org/article/a423cd753a2b4b63b631ea9c18878afa
Autor:
Jin Dong, Jiangqing Dong, Xin-He Yu, Yao-Chao Yan, Jia-Xu Nan, Bo He, Bao-Qin Ye, Wen-Chao Yang, Hong-Yan Lin, Guang-Fu Yang
Publikováno v:
Advanced Agrochem, Vol 1, Iss 2, Pp 174-181 (2022)
4-Hydrophenylpyruvate dioxygenase (HPPD), a key enzyme involved in tyrosine catabolism, has long been considered a promising target for herbicides and drugs. Several types of HPPD inhibitors have been developed as high-potency drugs or herbicides. Un
Externí odkaz:
https://doaj.org/article/9aa7e6bc183c4c999e703ceb994a0772
Autor:
Xiaoyan Zeng, Yurou Huang, Jing Dong, Xiaoxie Ma, Jia-Xu Nan, Weijie Chen, Hong-Yan Lin, Wen-Chao Yang, Xiaogang Liu, Jun Yin, Guang-Fu Yang
Publikováno v:
Advanced Agrochem, Vol 1, Iss 1, Pp 73-84 (2022)
The upregulation of 4-hydroxyphenylpyruvate dioxygenase (HPPD) can protect plants from adverse abiotic stress. Therefore, studying the changes of HPPD under abiotic stress is extremely valuable. In this study, we employed a rational molecular design
Externí odkaz:
https://doaj.org/article/bfcac10b054a4d8a92bd51d43edb9c4c
Autor:
Jin Dong, Xin-He Yu, Jiangqing Dong, Gao-Hua Wang, Xin-Long Wang, Da-Wei Wang, Yao-Chao Yan, Han Xiao, Bao-Qin Ye, Hong-Yan Lin, Guang-Fu Yang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 8/20/2024, Vol. 121 Issue 34, p1-11, 30p
Autor:
Hong-Yan Lin, Hong-Wei Han, Yin-Song Wang, De-Liu He, Wen-Xue Sun, Lu Feng, Zhong-Ling Wen, Min-Kai Yang, Gui-Hua Lu, Xiao-Ming Wang, Jin-Liang Qi, Yong-Hua Yang
Publikováno v:
Chinese Medicine, Vol 15, Iss 1, Pp 1-14 (2020)
Abstract Background Tamoxifen (TAM) is a cell type-specific anti-estrogen and is applied to improve the survival of patients with estrogen receptor positive (ER +) breast cancer. However, long-term TAM use can induce serious drug resistance, leading
Externí odkaz:
https://doaj.org/article/df00be6842d54f5eaec3dbbccef0f6f9
Publikováno v:
Trends in Biochemical Sciences. 48:568-584
Publikováno v:
ACS Omega, Vol 4, Iss 17, Pp 17366-17378 (2019)
Externí odkaz:
https://doaj.org/article/7fc19ea50ac64a109762711ae876a9cc
Autor:
Jia-Xu Nan, Jin Dong, Jun-Qiao Cao, Guang-Yi Huang, Xing-Xing Shi, Xue-Fang Wei, Qiong Chen, Hong-Yan Lin, Guang-Fu Yang
Publikováno v:
Journal of Agricultural and Food Chemistry. 71:5783-5795
Autor:
Jin Dong, Jiangqing Dong, Xin-He Yu, Yao-Chao Yan, Jia-Xu Nan, Bao-Qin Ye, Wen-Chao Yang, Hong-Yan Lin, Guang-Fu Yang
Publikováno v:
Journal of Agricultural and Food Chemistry. 71:1170-1177
High-potency 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitors are usually featured by time-dependent inhibition. However, the molecular mechanism underlying time-dependent inhibition by HPPD inhibitors has not been fully elucidated. Here, based