Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Hong Y, Choi"'
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 561 (2023)
ATP-binding cassette transporter A1 (ABCA1) has been identified as the molecular defect in Tangier disease. It is biochemically characterized by absence of high-density lipoprotein cholesterol (HDL-C) in the circulation, resulting in the accumulation
Externí odkaz:
https://doaj.org/article/a0bed07d30a14ac487fc298bdf61cace
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
The capacity of macrophages to dispose of cholesterol deposited in the atherosclerotic plaque depends on their ability to activate cholesterol efflux pathways. To develop athero-protective therapies aimed at promoting macrophage cholesterol efflux, c
Externí odkaz:
https://doaj.org/article/b0e9603fbf0a423aa5bc63539ff79bd4
Autor:
Hong Y. Choi, Iulia Iatan, Isabelle Ruel, Leslie Brown, Lindsay Hales, Shiwon Choi, Jacques Genest
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 43:609-617
The recent identification of the cell-surface protein DSC1 (desmocollin 1) as a negative regulator of HDL (high-density lipoprotein) biogenesis has attracted us to revisit the old HDL biogenesis hypothesis: HDL biogenesis reduces atherosclerosis. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ff80e67018fe1979434e133a20c0d2a
https://doi.org/10.1161/atvbaha.122.318275
https://doi.org/10.1161/atvbaha.122.318275
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Objective: Our recent studies showed that desmocollin 1 (DSC1) binds to apoA-I in order to inhibit apoA-I-mediated high density lipoprotein (HDL) biogenesis in atherosclerotic plaques. To promote HDL biogenesis in the plaque, here we search for small
Externí odkaz:
https://doaj.org/article/a3e31297f6cc4cdc84df9325136ada30
Publikováno v:
Endocrinology and Metabolism Clinics of North America. 51:557-572
Decades of research have shown that high-density lipoprotein cholesterol (HDL-C) levels in humans are associated with atherosclerotic cardiovascular disease (ASCVD). This association is strong and coherent across populations and remains after the eli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b8ed6d3dc0d31dd2d6e6d26a3ec8537
https://doi.org/10.1016/j.ecl.2022.01.003
https://doi.org/10.1016/j.ecl.2022.01.003
Autor:
Jacques Genest, Hong Y. Choi
Publikováno v:
Atherosclerosis. 345:39-40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ab540e06980fc3ce89586483f06c2d
https://doi.org/10.1016/j.atherosclerosis.2022.02.005
https://doi.org/10.1016/j.atherosclerosis.2022.02.005
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology
Frontiers in Pharmacology
Objective: Our recent studies showed that desmocollin 1 (DSC1) binds to apoA-I in order to inhibit apoA-I-mediated high density lipoprotein (HDL) biogenesis in atherosclerotic plaques. To promote HDL biogenesis in the plaque, here we search for small
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc69fe3c9ddb733fc508b7d5b113a42
https://doi.org/10.3389/fphar.2021.679456
https://doi.org/10.3389/fphar.2021.679456
Autor:
Hong Y Choi, Yun Liu, Christian Tennert, Yoshie Sugiura, Andromachi Karakatsani, Stephan Kröger, Eric B Johnson, Robert E Hammer, Weichun Lin, Joachim Herz
Publikováno v:
eLife, Vol 2 (2013)
ApoE, ApoE receptors and APP cooperate in the pathogenesis of Alzheimer’s disease. Intriguingly, the ApoE receptor LRP4 and APP are also required for normal formation and function of the neuromuscular junction (NMJ). In this study, we show that APP
Externí odkaz:
https://doaj.org/article/729afe712e7f427d8571088a9a1ccb06
Publikováno v:
Current Opinion in Cardiology. 33:311-316
Purpose of review Plasma levels of HDL cholesterol are a biomarker of cardiovascular health but not a therapeutic target, as demonstrated by the failure of pharmacological modulation of HDL cholesterol to prevent or treat atherosclerotic cardiovascul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c03a5c5d632f800f7b1c1650bdb028
https://doi.org/10.1097/hco.0000000000000508
https://doi.org/10.1097/hco.0000000000000508
Publikováno v:
Current Opinion in Lipidology. 29:36-41
Purpose of review The major cardio-protective function of HDL is to remove excess cellular cholesterol in the process of HDL particle formation and maturation. The HDL biogenic procedure requiring protein-lipid interactions has been incompletely unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c70414b3a46a6451e3eb9cbd87baa8a2
https://doi.org/10.1097/mol.0000000000000470
https://doi.org/10.1097/mol.0000000000000470