Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Hong Shuo Sun"'
Autor:
Limei Zhang, Guojian Zhao, Zhengwei Luo, Zining Yu, Gaigai Liu, Guangjun Su, Xiaolu Tang, Zhidong Yuan, Cheng Huang, Hong-Shuo Sun, Zhong-Ping Feng, Zhihua Huang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 178, Iss , Pp 117209- (2024)
A1 polarization of astrocytes mediated prolonged inflammation contributing to brain injury in ischemic stroke. We have previously shown that AD16 protects against neonatal hypoxic-ischemic brain damage in vivo and oxygen-glucose deprivation in vitro.
Externí odkaz:
https://doaj.org/article/903436583e544f98a3b5cbe5e141744d
SNAP-25, but not SNAP-23, is essential for photoreceptor development, survival, and function in mice
Autor:
Mengjia Huang, Chun Hin Chow, Akshay Gurdita, Hidekiyo Harada, Victor Q. B. Pham Truong, Sarah Eide, Hong-Shuo Sun, Zhong-Ping Feng, Philippe P. Monnier, Valerie A. Wallace, Shuzo Sugita
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract SNARE-mediated vesicular transport is thought to play roles in photoreceptor glutamate exocytosis and photopigment delivery. However, the functions of Synaptosomal-associated protein (SNAP) isoforms in photoreceptors are unknown. Here, we re
Externí odkaz:
https://doaj.org/article/b9879e6b53ed4557a4ce88532d44b2b2
Autor:
Ye Peng, Jun-rui Ye, Sha-sha Wang, Wen-bin He, Zhong-ping Feng, Hong-shuo Sun, Shi-feng Chu, Zhao Zhang, Nai-hong Chen
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-17 (2023)
Abstract Parkinson’s disease (PD) is pathologically manifested by the aggregation of α-synuclein, which has been envisioned as a promising disease-modifying target for PD. Here, we identified 20C, a bibenzyl compound derived from Gastrodia elata,
Externí odkaz:
https://doaj.org/article/c502ea60b4eb41b9afd18262f3212636
Autor:
Wen-yu Ma, Qing-lin Wu, Sha-sha Wang, Hong-yun Wang, Jun-rui Ye, Hong-shuo Sun, Zhong-ping Feng, Wen-bin He, Shi-feng Chu, Zhao Zhang, Nai-hong Chen
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-23 (2023)
Abstract Ischemic stroke is characterized by the presence of reactive microglia. However, its precise involvement in stroke etiology is still unknown. We used metabolic profiling and showed that chemokine like factor 1 (CKLF1) causes acute microglial
Externí odkaz:
https://doaj.org/article/7f8bc31b84224e17b6bcd65f5948714d
Autor:
Mengjia Huang, Na-Ryum Bin, Jayant Rai, Ke Ma, Chun Hin Chow, Sarah Eide, Hidekiyo Harada, Jianbing Xiao, Daorong Feng, Hong-Shuo Sun, Zhong-Ping Feng, Herbert Y. Gaisano, Jeffrey E. Pessin, Philippe P. Monnier, Kenichi Okamoto, Liang Zhang, Shuzo Sugita
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106664- (2023)
Summary: SNARE-mediated membrane fusion plays a crucial role in presynaptic vesicle exocytosis and also in postsynaptic receptor delivery. The latter is considered particularly important for synaptic plasticity and learning and memory, yet the identi
Externí odkaz:
https://doaj.org/article/3e434672cf0e4a088f5a59acf5406521
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
Objective: Therapeutic hypothermia (TH) is the current standard of care for neonatal hypoxic-ischemic encephalopathy (HIE), yet morbidity and mortality remain significant. Adjuvant neuroprotective agents have been suggested to augment hypothermic-med
Externí odkaz:
https://doaj.org/article/ab7c7dc6360f424a83f4119e033eb693
Autor:
Nancy Dong, Julia Bandura, Zhaolei Zhang, Yan Wang, Karine Labadie, Benjamin Noel, Angus Davison, Joris M. Koene, Hong-Shuo Sun, Marie-Agnès Coutellec, Zhong-Ping Feng
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-25 (2021)
Abstract Background The pond snail Lymnaea stagnalis (L. stagnalis) has been widely used as a model organism in neurobiology, ecotoxicology, and parasitology due to the relative simplicity of its central nervous system (CNS). However, its usefulness
Externí odkaz:
https://doaj.org/article/42deca5416ba433e8c9820699cea952f
Publikováno v:
Frontiers in Digital Health, Vol 3 (2021)
Regular blood pressure (BP) monitoring enables earlier detection of hypertension and reduces cardiovascular disease. Cuff-based BP measurements require equipment that is inconvenient for some individuals and deters regular home-based monitoring. Sinc
Externí odkaz:
https://doaj.org/article/f9201cd68cd349bca01ee753d037c899
Autor:
Hong-Bin Lin, Ying-Hui Lin, Jin-Yu Zhang, Wen-Jing Guo, Andrea Ovcjak, Zhi-Jian You, Zhong-Ping Feng, Hong-Shuo Sun, Feng-Xian Li, Hong-Fei Zhang
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Ischemic stroke remains a devastating disease which is the leading cause of death worldwide. Visual impairment after stroke is a common complication which may lead to vision loss, greatly impacting life quality of patients. While ischemic stroke is t
Externí odkaz:
https://doaj.org/article/49dd3a7609d64a4a97abf165064bc6d0
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2021)
Alzheimer's disease (AD) is a neurodegenerative disorder associated with continual decline in cognition and ability to perform routine functions such as remembering familiar places or understanding speech. For decades, amyloid beta (Aβ) was viewed a
Externí odkaz:
https://doaj.org/article/7ca07ba4f41141e180303a7305df3475