Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Hong S Lu"'
Autor:
Na Wang, Lishu He, Hui Lin, Lunbo Tan, Yuan Sun, Xiaoying Zhang, A H Jan Danser, Hong S Lu, Yongcheng He, Xifeng Lu
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0225356 (2020)
High plasma LDL cholesterol (LDL-c) concentration is a major risk factor for atherosclerosis. Hepatic LDL receptor (LDLR) regulates LDL metabolism, and thereby plasma LDL-c concentration. Recently, we have identified the (pro)renin receptor [(P)RR] a
Externí odkaz:
https://doaj.org/article/48567772fdb54c3cb959de5c46f8d188
Autor:
Hisashi Sawada, MD, PhD, Zachary A. Beckner, BS Candidate, Sohei Ito, MD, PhD, Alan Daugherty, PhD, DSc, Hong S. Lu, MD, PhD
Publikováno v:
JVS - Vascular Science, Vol 3, Iss , Pp 64-72 (2022)
The mechanistic basis for the formation of aortic aneurysms and dissection needs to be elucidated to facilitate the development of effective medications. β-Aminopropionitrile administration in mice has been used frequently to study the pathologic fe
Externí odkaz:
https://doaj.org/article/2fa8c548ee814d34914889a2c352832a
Autor:
Shayan Mohammadmoradi, Hisashi Sawada, Sohei Ito, Adam E. Mullick, Deborah A. Howatt, Michael Franklin, Hong S. Lu, Alan Daugherty
Publikováno v:
JVS - Vascular Science, Vol 4, Iss , Pp 100161- (2023)
Externí odkaz:
https://doaj.org/article/f50d2489fcbb441e8cecdffa18fc3285
Autor:
Hong S. Lu, Alan Daugherty
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
To respond to the NIH's policy for rigor and reproducibility in preclinical research, many journals have implemented guidelines and checklists to guide authors in improving the rigor and reproducibility of their research. Transparency in developing d
Externí odkaz:
https://doaj.org/article/cf59f52275874acd82130f7df91957d6
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/89666659e3fa44eab6c294f1e6515d06
Autor:
Dien Ye, Xiaofei Yang, Liwei Ren, Hong S. Lu, Yuan Sun, Hui Lin, Lunbo Tan, Na Wang, Genevieve Nguyen, Michael Bader, Adam E. Mullick, A. H. Jan Danser, Alan Daugherty, Yizhou Jiang, Yidan Sun, Furong Li, Xifeng Lu
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Objective: Elevated plasma cholesterol concentrations contributes to ischemic cardiovascular diseases. Recently, we showed that inhibiting hepatic (pro)renin receptor [(P)RR] attenuated diet-induced hypercholesterolemia and hypertriglyceridemia in lo
Externí odkaz:
https://doaj.org/article/9afa4c3acbca4a4285530bd6e4d40d51
Autor:
Masayoshi Kukida, Hisashi Sawada, Satoko Ohno‐Urabe, Deborah A. Howatt, Jessica J. Moorleghen, Marko Poglitsch, Alan Daugherty, Hong S. Lu
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/e16c7f4835ac4c8ca5a5bc6711088253
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 339 (2022)
Aortic aneurysms and dissections are life-threatening conditions that have a high risk for lethal bleeding and organ malperfusion. Many studies have investigated the molecular basis of these diseases using mouse models. In mice, ex vivo, in situ, and
Externí odkaz:
https://doaj.org/article/447ab8000a864e72bb5d26b34706166a
Publikováno v:
Journal of the American College of Cardiology. 81:1260-1262
Autor:
Hisashi Sawada, Satoko Ohno-Urabe, Dien Ye, Michael K. Franklin, Jessica J. Moorleghen, Deborah A. Howatt, Adam E. Mullick, Alan Daugherty, Hong S. Lu
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology, 42(10), 1254-1261. Lippincott Williams & Wilkins
Background: Cross-linking of lysine residues in elastic and collagen fibers is a vital process in aortic development. Inhibition of lysyl oxidase by BAPN (β-aminopropionitrile) leads to thoracic aortopathies in mice. Although the renin-angiotensin s