Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Hong Ro Kim"'
Autor:
Seung Joon Lee, Won Suk Lee, Eun-Jin Go, Hannah Yang, Hong Ro Kim, Bong-Seog Kim, Chan Kim, Hong Jae Chon
Publikováno v:
Cancer Research. 83:1800-1800
Background: PI3Kδ and PI3Kγ are mainly expressed in leukocytes, indicating that they are involved in immune modulation of the tumor microenvironment (TME). Additionally, DNA-dependent protein kinase (DNA-PK) plays a pivotal role as a mediator in re
Autor:
Shailesh R. Satpute, Brian Berman, Ming Tan, Kamal D. Moudgil, James E. Simon, Rajesh Rajaiah, Qingli Wu, Hong Ro Kim
Publikováno v:
The Journal of Nutrition. 138:2111-2116
Green tea, a product of the dried leaves of Camellia sinensis, is the most widely consumed beverage in the world. The polyphenolic compounds from green tea (PGT) possess antiinflammatory properties. We investigated whether PGT can afford protection a
Publikováno v:
The Journal of Immunology. 177:6634-6641
Many autoimmune diseases are believed to involve primarily T cell-mediated effector mechanisms. There is increasing realization, however, that Abs may also play a vital role in the propagation of T cell-driven disorders. In this study, on the rat adj
Publikováno v:
The Journal of Immunology. 175:219-227
Dimethyl dioctadecyl ammonium bromide (DDA) (C38H80NBr) is a nonantigenic lipoid material. DDA-induced arthritis (DIA) in the Lewis (LEW) (RT.1l) rat is a new experimental model for human rheumatoid arthritis (RA). DIA is a T cell-mediated autoimmune
Publikováno v:
The Journal of Immunology. 173:181-188
The 65-kDa mycobacterial heat shock protein (Bhsp65) has been invoked in the pathogenesis of both adjuvant arthritis (AA) in the Lewis rat (RT.1l) and human rheumatoid arthritis. Arthritic Lewis rats in the late phase of AA show diversification of th
Publikováno v:
IUBMB Life. 48:429-433
HSP90 is one of the most abundant heat shock proteins (HSPs) in eukaryotic cells and is found in complex with several regulatory proteins such as kinases and transcription factors. Geldanamycin (GA), a benzoquinone ansamycin, specifically binds to HS
Publikováno v:
IUBMB Life. 48:425-428
Geldanamycin (GA), a benzoquinone ansamycin, is one of the specific inhibitors of 90-kDa heat shock protein and induces growth inhibition and apoptosis in certain cancer cell lines. We have investigated the mechanism of GA-induced growth inhibition i
Publikováno v:
The Journal of rheumatology. 34(11)
In autoimmune situations, the outcome of immune response against a disease-related antigen is typically viewed in terms of the balance between the pathogenic versus the protective subsets of antigen-reactive T cells. Using the rat adjuvant arthritis
Autor:
Sin Hye Cho, Hong Ro Kim, Jung Mogg Kim, Eunkyeong Jang, Sang-Koo Lee, Jeehee Youn, Doo-Jin Paik
Publikováno v:
Arthritis and rheumatism. 54(2)
Objective K/BxN-transgenic mice are a model of autoimmune arthritis, similar to rheumatoid arthritis. This study was undertaken to determine whether inhibition of lymphopenia-provoked homeostatic expansion can prevent spontaneous development of disea
Publikováno v:
Journal of biochemistry. 126(6)
In eukaryotic cells, HSP90 is associated with several protein kinases and regulates their activities. HSP90 was also reported to possess an autophosphorylase activity. In this study, we examined in vitro autophosphorylation of HSP90, which was purifi