Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Hong Quach"'
Autor:
Calvin Chi, Olivia Solomon, Caroline Shiboski, Kimberly E. Taylor, Hong Quach, Diana Quach, Lisa F. Barcellos, Lindsey A. Criswell
Publikováno v:
PLoS ONE, Vol 18, Iss 3 (2023)
Heterogeneity in Sjögren’s syndrome (SS), increasingly called Sjögren’s disease, suggests the presence of disease subtypes, which poses a major challenge for the diagnosis, management, and treatment of this autoimmune disorder. Previous work di
Externí odkaz:
https://doaj.org/article/5cf9d5e1391c46a78718a37c70bcff07
Autor:
Brooke Rhead, Xiaorong Shao, Jennifer S. Graves, Tanuja Chitnis, Amy T. Waldman, Timothy Lotze, Teri Schreiner, Anita Belman, Lauren Krupp, Benjamin M. Greenberg, Bianca Weinstock–Guttman, Gregory Aaen, Jan M. Tillema, Moses Rodriguez, Janace Hart, Stacy Caillier, Jayne Ness, Yolanda Harris, Jennifer Rubin, Meghan S. Candee, Mark Gorman, Leslie Benson, Soe Mar, Ilana Kahn, John Rose, T. Charles Casper, Hong Quach, Diana Quach, Catherine Schaefer, Emmanuelle Waubant, Lisa F. Barcellos, the US Network of Pediatric MS Centers
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 6, Pp 1053-1061 (2019)
Abstract Objective Onset of multiple sclerosis (MS) occurs in childhood for approximately 5% of cases (pediatric MS, or ped‐MS). Epigenetic influences are strongly implicated in MS pathogenesis in adults, including the contribution from microRNAs (
Externí odkaz:
https://doaj.org/article/7e4b193be7ec429facf7230a6a5acd9e
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0255549 (2021)
[This corrects the article DOI: 10.1371/journal.pone.0248429.].
Externí odkaz:
https://doaj.org/article/9dae9acd9df74a2daea59c7b80626311
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0248429 (2021)
Differential methylation of immune genes has been a consistent theme observed in Sjögren's syndrome (SS) in CD4+ T cells, CD19+ B cells, whole blood, and labial salivary glands (LSGs). Multiple studies have found associations supporting genetic cont
Externí odkaz:
https://doaj.org/article/c11b66334bc24771b69701ce39d609d6
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230884 (2020)
Endothelial cells are a primary site of leukocyte recruitment during inflammation. An increase in tumor necrosis factor-alpha (TNFa) levels as a result of infection or some autoimmune diseases can trigger this process. Several autoimmune diseases are
Externí odkaz:
https://doaj.org/article/cc20f204e6b84325b1868b34855d90b8
Autor:
Olivia Solomon, Julie MacIsaac, Hong Quach, Gwen Tindula, Michael S. Kobor, Karen Huen, Michael J. Meaney, Brenda Eskenazi, Lisa F. Barcellos, Nina Holland
Publikováno v:
Epigenetics, Vol 13, Iss 6, Pp 655-664 (2018)
Analysis of DNA methylation helps to understand the effects of environmental exposures as well as the role of epigenetics in human health. Illumina, Inc. recently replaced the HumanMethylation450 BeadChip (450K) with the EPIC BeadChip, which nearly d
Externí odkaz:
https://doaj.org/article/8340d24672c84fb7b92507e4afdfdbfe
Autor:
Brooke Rhead, Ina S Brorson, Tone Berge, Cameron Adams, Hong Quach, Stine Marit Moen, Pål Berg-Hansen, Elisabeth Gulowsen Celius, Dipen P Sangurdekar, Paola G Bronson, Rodney A Lea, Sean Burnard, Vicki E Maltby, Rodney J Scott, Jeannette Lechner-Scott, Hanne F Harbo, Steffan D Bos, Lisa F Barcellos
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0206511 (2018)
DNA methylation is an epigenetic mark that is influenced by environmental factors and is associated with changes to gene expression and phenotypes. It may link environmental exposures to disease etiology or indicate important gene pathways involved i
Externí odkaz:
https://doaj.org/article/f7193d155a0b49f58deed8a0dedea550
Autor:
Annette Langer-Gould, Robyn Lucas, Anny H. Xiang, Lie H. Chen, Jun Wu, Edlin Gonzalez, Samantha Haraszti, Jessica B. Smith, Hong Quach, Lisa F. Barcellos
Publikováno v:
Nutrients, Vol 10, Iss 3, p 268 (2018)
Multiple sclerosis (MS) incidence and serum 25-hydroxyvitamin D (25OHD) levels vary by race/ethnicity. We examined the consistency of beneficial effects of 25OHD and/or sun exposure for MS risk across multiple racial/ethnic groups. We recruited incid
Externí odkaz:
https://doaj.org/article/2bbbfbde0a914ee79d575e7055a12b82
Autor:
Annette Langer-Gould, Robyn M. Lucas, Anny H. Xiang, Jun Wu, Lie H. Chen, Edlin Gonzales, Samantha Haraszti, Jessica B. Smith, Hong Quach, Lisa F. Barcellos
Publikováno v:
Nutrients, Vol 10, Iss 2, p 184 (2018)
Blacks have different dominant polymorphisms in the vitamin D-binding protein (DBP) gene that result in higher bioavailable vitamin D than whites. This study tested whether the lack of association between 25-hydroxyvitamin D (25OHD) and multiple scle
Externí odkaz:
https://doaj.org/article/5fdcc12ef9384c1ab40d8dd9c53f8686
Autor:
Steffan D Bos, Christian M Page, Bettina K Andreassen, Emon Elboudwarej, Marte W Gustavsen, Farren Briggs, Hong Quach, Ingvild S Leikfoss, Anja Bjølgerud, Tone Berge, Hanne F Harbo, Lisa F Barcellos
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0117403 (2015)
Determine whether MS-specific DNA methylation profiles can be identified in whole blood or purified immune cells from untreated MS patients.Whole blood, CD4+ and CD8+ T cell DNA from 16 female, treatment naïve MS patients and 14 matched controls was
Externí odkaz:
https://doaj.org/article/cef36fcc044540e299fe4568b13bea96