Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Hong Q. Smith"'
Autor:
Emily W. Helm, Amy M. Peiper, Matthew Phillips, Caroline G. Williams, Michael B. Sherman, Theresa Kelley, Hong Q. Smith, Sorin O. Jacobs, Dhairya Shah, Sarah M. Tatum, Neha Iyer, Marco Grodzki, Joyce C. Morales Aparicio, Elizabeth A. Kennedy, Mikayla S. Manzi, Megan T. Baldridge, Thomas J. Smith, Stephanie M. Karst
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Noroviruses are the leading cause of severe childhood diarrhea and foodborne disease worldwide. While they are a major cause of disease in all age groups, infections in the very young can be quite severe with annual estimates of 50,000-200,000 fatali
Externí odkaz:
https://doaj.org/article/977826bdb7f747619d7e66707745bdfc
Autor:
Michael B. Sherman, Alexis N. Williams, Hong Q. Smith, B. Montgomery Pettitt, Christiane E. Wobus, Thomas J. Smith
Publikováno v:
Viruses, Vol 13, Iss 11, p 2162 (2021)
Noroviruses are responsible for almost a fifth of all cases of gastroenteritis worldwide. The calicivirus capsid is composed of 180 copies of VP1 with a molecular weight of ~58 kDa. This coat protein is divided into the N-terminus (N), the shell (S)
Externí odkaz:
https://doaj.org/article/05de2b4e581245df82b16756955a039b
Publikováno v:
Viruses, Vol 12, Iss 6, p 618 (2020)
Protein-shelled viruses have been thought as “tin cans” that merely carry the genomic cargo from cell to cell. However, through the years, it has become clear that viruses such as rhinoviruses and caliciviruses are active and dynamic structures w
Externí odkaz:
https://doaj.org/article/76939ba3cd4e49f4a3626e448f3aa154
Autor:
Abimbola O. Kolawole, Hong Q. Smith, Sophia A. Svoboda, Madeline S. Lewis, Michael B. Sherman, Gillian C. Lynch, B. Montgomery Pettitt, Thomas J. Smith, Christiane E. Wobus
Publikováno v:
mSphere, Vol 2, Iss 5 (2017)
ABSTRACT Ideal antiviral vaccines elicit antibodies (Abs) with broad strain recognition that bind to regions that are difficult to mutate for escape. Using 10 murine norovirus (MNV) strains and 5 human norovirus (HuNoV) virus-like particles (VLPs), w
Externí odkaz:
https://doaj.org/article/8c3e915739ee40cdb50d1aac4ea2b75c
Autor:
Hong Q. Smith, Thomas J. Smith
Publikováno v:
Viruses, Vol 11, Iss 3, p 235 (2019)
Noroviruses are responsible for almost a fifth of all cases of gastroenteritis worldwide. New strains evolve every 2–4 years by escaping herd immunity and cause worldwide epidemics. In the US alone, noroviruses are responsible for ~20 million cases
Externí odkaz:
https://doaj.org/article/db2b3bc8d4754651be6295c0693b554a
Autor:
Hong Q. Smith, Christiane E. Wobus, B. Montgomery Pettitt, Alexis N. Williams, Thomas J. Smith, Michael B. Sherman, Stefan Taube
Publikováno v:
J Virol
Human norovirus is the leading cause of gastroenteritis worldwide, with no approved vaccine or antiviral treatment to mitigate infection. These plus-strand RNA viruses have T = 3 icosahedral protein capsids with 90 pronounced protruding (P) domain di
Autor:
Thomas J. Smith, Christiane E. Wobus, Alexis N. Williams, Hong Q. Smith, B. Montgomery Pettitt, Michael B. Sherman
Publikováno v:
Viruses
Viruses, Vol 13, Iss 2162, p 2162 (2021)
Viruses, Vol 13, Iss 2162, p 2162 (2021)
Noroviruses are responsible for almost a fifth of all cases of gastroenteritis worldwide. The calicivirus capsid is composed of 180 copies of VP1 with a molecular weight of ~58 kDa. This coat protein is divided into the N-terminus (N), the shell (S)
Autor:
B. Montgomery Pettitt, Thomas J. Smith, Christiane E. Wobus, Michael B. Sherman, Stefan Taube, Alexis N. Williams, Hong Q. Smith
Publikováno v:
J Virol
Noroviruses, members of the Caliciviridae family, are the major cause of epidemic gastroenteritis in humans, causing ∼20 million cases annually. These plus-strand RNA viruses have T=3 icosahedral protein capsids with 90 pronounced protruding (P) do
Publikováno v:
Viruses, Vol 12, Iss 618, p 618 (2020)
Viruses
Viruses
Protein-shelled viruses have been thought as “tin cans” that merely carry the genomic cargo from cell to cell. However, through the years, it has become clear that viruses such as rhinoviruses and caliciviruses are active and dynamic structures w
Publikováno v:
Neurochemical Research. 44:117-132
In-vitro, glutamate dehydrogenase (GDH) catalyzes the reversible oxidative deamination of glutamate to α-ketoglutarate (α-KG). GDH is found in all organisms, but in animals is allosterically regulated by a wide array of metabolites. For many years,