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pro vyhledávání: '"Hong Ning Fu"'
Autor:
Arba L. Ager, James K. Wood, Hong Ning Fu, Jonathan L. Vennerstrom, William Y. Ellis, Wilbur K. Milhous, Lucia Gerena, Steven L. Andersen
Publikováno v:
Journal of Medicinal Chemistry. 35:3023-3027
Dispiro-1,2,4,5-tetraoxanes 2-4 were synthesized as potential peroxide antimalarial drugs. They had curative activity against Plasmodium berghei in vivo at single doses of 320 and 640 mg/kg which confirms earlier unpublished data. Moreover, artemisin