Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Hong Ming Shen"'
Autor:
Feng-Jun Du, Yue-Qing Huang, Ren-Fang Han, Min Huang, Zhen-Yu Jia, Hong-Ming Shen, Jian-Jun Yao, Han Min, Chun-Hua Zhao
Publikováno v:
Journal of Public Health.
Autor:
Amy L. Kenter, Yee Ling Wu, Saurabh Priyadarshi, Robert Wuerffel, Xue Lei, Jie Liang, Jose F. Cantillo, Hong Ming Shen
Publikováno v:
Cell reports. 37(8)
Class-switch recombination (CSR) involves replacement of the Cμ constant region with another downstream CH region. CSR is initiated by activation-induced cytidine deaminase (AID)-mediated DNA breaks that are targeted to transcriptionally active swit
Publikováno v:
IET Generation, Transmission & Distribution. 9:838-844
Commutation failure (CF) may be caused by AC fault in AC/DC interconnected system, and it will affect the performance of distance protection. The transient characteristic of equivalent current of power-frequency of the dc–ac inverter is first analy
Publikováno v:
Advanced Materials Research. :1671-1677
The main problem for transformer protection is still how to identify inrush current. The inrush current is likely to occur when the transformer is closed with no-load or when the voltage recovers after fault. False operation may take place for the in
Publikováno v:
The Journal of Experimental Medicine
The process of somatic hypermutation (SHM) of immunoglobulin (Ig) genes requires activation-induced cytidine deaminase (AID). Although mistargeting of AID is detrimental to genome integrity, the mechanism and the cis-elements responsible for targetin
Publikováno v:
Cell Cycle. 8:3097-3101
The somatic hypermutation (SHM) process is initiated in activated B lymphocytes by the cytosine DNA deaminase AID creating uracils that are further treated by DNA replication and/or error-prone base excision repair (BER) and/or error-prone mismatch r
Publikováno v:
Molecular and Cellular Biology. 25:10815-10821
Activation-induced deaminase (AID) initiates immunoglobulin somatic hypermutation (SHM). Since in vitro AID was shown to deaminate cytosines on single-stranded DNA or the nontranscribed strand, it remained a puzzle how in vivo AID targets both DNA st
Publikováno v:
Immunity. 19:235-242
The frequency of somatic hypermutations of an Ig κ transgene with an artificial test insert, RS, is at least 4-fold higher than that of three related transgenes. The four transgenes differ only in the sequence of a 96 bp insert within the variable r
Publikováno v:
International Immunology. 13:665-674
We have created a kappa transgene in which a polymerase (pol) III promoter replaces the pol II promoter. Two independent transgenic lines show somatic hypermutation of the transgene in B cells from hyperimmunized mice. Both lines transcribe transgene
Publikováno v:
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 356:13-19
Somatic hypermutation (SHM) of immunoglobulin (Ig) genes is a highly specific mechanism restricted to B lymphocytes during only a few cell generations. Data presented here suggest that transcription of the target genes is required, but not sufficient