GPC3 as a potential diagnostic and prognostic marker for lung adenocarcinoma

Autor: Wei-qin Wu, Qing-song Sun, Li-li Gao, Ya-juan Jia, Hong-mei Zhao, Hong Sun, Xiang Han

Publikováno v: Biotechnology & Biotechnological Equipment, Vol 38, Iss 1 (2024)

We designed this study to identify potential diagnostic and prognostic markers for lung adenocarcinoma (LUAD). Four gene expression profiles were downloaded from GEO and merged into a training cohort, and those genes that were differentially expresse

Externí odkaz: https://doaj.org/article/dd9efc54f8bd4b9483d3ee12e6070c21

Emergence of Antifungal Resistant Subclades in the Global Predominant Phylogenetic Population of Candida albicans

Autor: Jie Gong, Xin-Fei Chen, Xin Fan, Juan Xu, Han Zhang, Ruo-Yu Li, Sharon C-A Chen, Fanrong Kong, Shu Zhang, Zi-Yong Sun, Mei Kang, Kang Liao, Da-Wen Guo, Zhe Wan, Zhi-Dong Hu, Yun-Zhuo Chu, Hong-Mei Zhao, Gui-Ling Zou, Chong Shen, Yuan-Yuan Geng, Wei-Wei Wu, He Wang, Fei Zhao, Xin Lu, Li-Hua He, Gui-Ming Liu, Ying-Chun Xu, Jian-Zhong Zhang, Meng Xiao

Publikováno v: Microbiology Spectrum, Vol 11, Iss 1 (2023)

ABSTRACT Candida albicans remains the most common species causing invasive candidiasis. In this study, we present the population structure of 551 global C. albicans strains. Of these, the antifungal susceptibilities of 370 strains were tested. Specif

Externí odkaz: https://doaj.org/article/3b6082d412814a8e95b4215d04ec17b1

Characteristics and prognostic significance of genetic mutations in acute myeloid leukemia based on a targeted next‐generation sequencing technique

Autor: Rui‐Qi Wang, Chong‐Jian Chen, Yu Jing, Jia‐Yue Qin, Yan Li, Guo‐Feng Chen, Wei Zhou, Yong‐Hui Li, Juan Wang, Da‐Wei Li, Hong‐Mei Zhao, Bian‐Hong Wang, Li‐Li Wang, Hong Wang, Meng‐Zhen Wang, Xiao‐Ning Gao, Li Yu

Publikováno v: Cancer Medicine, Vol 9, Iss 22, Pp 8457-8467 (2020)

Abstract To explore the characteristics and prognostic significance of genetic mutations in acute myeloid leukemia (AML), we screened the gene mutation profile of 171 previously untreated AML patients using a next‐generation sequencing technique ta

Externí odkaz: https://doaj.org/article/b742c1516cd64c8d84fc380bac60ab71

Overexpression of tripartite motif containing 26 inhibits non‐small cell lung cancer cell growth by suppressing PI3K/AKT signaling

Autor: Jia‐Li Tao, Man Luo, Hong Sun, Hong‐Mei Zhao, Qing‐Song Sun, Zi‐Ming Huang

Publikováno v: Kaohsiung Journal of Medical Sciences, Vol 36, Iss 6, Pp 417-422 (2020)

Abstract It has been reported that tripartite motif containing 26 (TRIM26) is involved in the tumorigenesis of some cancers, but its function in non‐small cell lung cancer (NSCLC) is still unclear. In this study, we found that TRIM26 was markedly d

Externí odkaz: https://doaj.org/article/479c7e4a60ea41c9b129327cbcc6ca15

Continual Decline in Azole Susceptibility Rates in Candida tropicalis Over a 9-Year Period in China

Autor: Yao Wang, Xin Fan, He Wang, Timothy Kudinha, Ya-Ning Mei, Fang Ni, Yu-Hong Pan, Lan-Mei Gao, Hui Xu, Hai-Shen Kong, Qing Yang, Wei-Ping Wang, Hai-Yan Xi, Yan-Ping Luo, Li-Yan Ye, Meng Xiao, China Hospital Invasive Fungal Surveillance Net (CHIF-NET) Study Group, Zi-Yong Sun, Zhong-Jv Chen, Ying-Chun Xu, Mei Kang, Yu-Ling Xiao, Kang Liao, Peng-Hao Guo, Hua Yu, Lin Yin, Da-Wen Guo, Lan-Ying Cui, Peng-Peng Liu, Hong He, Yan Jin, Hui Fan, Yun-Song Yu, Jie Lin, Ruo-Yu Li, Zhe Wan, Ling Ma, Shuai-Xian Du, Wen-En Liu, Yan-Ming Li, Tie-Li Zhou, Qing Wu, Xin-Lan Hu, Ning Li, Rong Zhang, Hong-Wei Zhou, Yi-Min Li, Dan-Hong Su, Qiang-Qiang Zhang, Li Li, Yun Xia, Li Yan, Zhi-Dong Hu, Na Yue, Yan Jiang, Zhi-Yong Liu, Yu-Ting Zheng, Wei Cao, Yun-Zhuo Chu, Fu-Shun Li, Yun Liu, Yuan-Hong Xu, Ying Huang, Wei Jia, Gang Li, Huo-Xiang Lv, Qing-Feng Hu, Xiu-Li Xu, Xiao-Yan Chen, Xiao-Ling Ma, Huai-Wei Lu, Yin-Mei Yang, Hui-Ling Chen, Jian-Sheng Huang, Hui Jing, Bin San, Yan Du, Hong-Jie Liang, Bin Yang, Yu-Lan Lin, Shan-Mei Wang, Qiong Ma, Hong-Mei Zhao, Li-Wen Liu, Qing Zhang, Fei Xia, Jin-Ying Wu, Mao-Li Yi, Xiang-Yang Chen, Wei-Ping Lu, Xiao-Yan Zeng, Jing Zhang, Jing Wang, Xiao-Guang Xiao, Jia-Yin Liang, Fan-Hua Huang, Gui-Ling Zou, Xue-Fei Du, Xiao-Ming Wang, Xu-Feng Ji, Yong Liu, Zhi-Jie Zhang, Yu-Xing Ni, Sheng-Yuan Zhao, Xiu-Lan Song, Chun-Yan Xu, Lin Meng, Xian-Feng Zhang, Jian-Hong Zhao, Hong-Lian Wei, Xue-Song Xu, Weil Li, Yu-Ping Wang, Mei Xu, Yun-Duo Wang, Jing Song, Tian-Pen Cui, Zhi-Min Hu, Ting-Yin Zhou, Hai-Qing Hu, Xiao-Min Xu, Shan-Yan Liang, Lin-Qiang Deng, Hui Chen, Xiao-Jun Sun, Hai-Bin Wang, Jian-Bang Kang, Tie-Ying Hou, Ping Ji, Na Chen, Wen-Jun Sui, Hai-Tong Gu, Xiao-Qin Ha, Yuan-Yuan Zhang, Shu-Feng Wang, Hong Lu, Yi-Hai Gu, Xuan Hou, Rong Tang, Yan-Yan Guo, Fei Huang, Long-Hua Hu, Xiao-Yan Hu, Juan Li, Lian-Hua Wei, Dan Liu, Yan-Qiu Han, Yi-Hui Yao, Jian-Sheng Wang, Jie Wang, Wei Li, Li-Ping Ning, Wei-Qing Song, Yu-Jie Wang, Liang Luan

Publikováno v: Frontiers in Microbiology, Vol 12 (2021)

BackgroundThere have been reports of increasing azole resistance in Candida tropicalis, especially in the Asia-Pacific region. Here we report on the epidemiology and antifungal susceptibility of C. tropicalis causing invasive candidiasis in China, fr

Externí odkaz: https://doaj.org/article/f5afcd8390ff4114824aab7f3902e06d