Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Hong Lim Kim"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Recently, we demonstrated that the corpora amylacea (CA), a glycoprotein-rich aggregate frequently found in aged brains, accumulates in the ischemic hippocampus and that osteopontin (OPN) mediates the entire process of CA formation. Therefore, this s
Externí odkaz:
https://doaj.org/article/2a376c8f08f847cdb486ca6b5f25fb16
Autor:
Myeong-Suk Bahn, Dong-Min Yu, Myoungwoo Lee, Sung-Je Jo, Ji-Won Lee, Ho-Chul Kim, Hyun Lee, Hong Lim Kim, Arum Kim, Jeong-Ho Hong, Jun Seok Kim, Seung-Hoi Koo, Jae-Seon Lee, Young-Gyu Ko
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Bahn et al explore the role of the lipid raft protein Prominin-1 in liver regeneration. They show that Prominin-1 promotes hepatocyte proliferation after acute liver injury by interacting with the signal transducer GP130, confining it to lipid rafts
Externí odkaz:
https://doaj.org/article/44a2b730a3d24d5aa6b5b8449e0f3f16
Autor:
Jin Won Kim, Sun Ah Nam, Eunjeong Seo, Jong Young Lee, Dohui Kim, Ji Hyeon Ju, Sun Woo Lim, Hong Lim Kim, Hyung Wook Kim, Chul Woo Yang, Jin Kim, Dong Sung Kim, Yong Kyun Kim
Publikováno v:
The Korean Journal of Internal Medicine, Vol 36, Iss 6, Pp 1420-1436 (2021)
Background/Aims Tacrolimus has been used as an immunosuppressive agent in organ transplantation. Despite the therapeutic benefits, tacrolimus’s use is limited due to its nephrotoxicity. To reduce tacrolimus nephrotoxicity, effective humanized exper
Externí odkaz:
https://doaj.org/article/1cdcf2c8f8544d2a884a0e270371f0bb
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Macrophages play a crucial role in wound healing and fibrosis progression after brain injury. However, a detailed analysis of their initial infiltration and interaction with fibroblasts is yet to be conducted. This study aimed to investigate the poss
Externí odkaz:
https://doaj.org/article/c23ef133c10f4243b9261117695c16ae
Autor:
Sheng Cui, Kang Luo, Yi Quan, Sun Woo Lim, Yoo Jin Shin, Kyung Eun Lee, Hong Lim Kim, Eun Jeong Ko, Ju Hwan Kim, Sang J. Chung, Soo Kyung Bae, Byung Ha Chung, Chul Woo Yang
Publikováno v:
The Korean Journal of Internal Medicine, Vol 36, Iss 4, Pp 949-961 (2021)
Background/Aims Coenzyme Q10 (CoQ10), is a promising antioxidant; however, low bioavailability owing to lipid-solubility is a limiting factor. We developed water-soluble CoQ10 (CoQ10-W) and compared its effects with conventional lipid-soluble CoQ10 (
Externí odkaz:
https://doaj.org/article/afb827b003b848628aa950b50b5b079d
Autor:
Soon-Young Jung, Tae-Ryong Riew, Hye Hyeon Yun, Ji Hee Lim, Ji-Won Hwang, Sung Won Jung, Hong Lim Kim, Jae-Seon Lee, Mun-Yong Lee, Jeong-Hwa Lee
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9635 (2023)
Bcl-2-interacting cell death suppressor (BIS), also called BAG3, plays a role in physiological functions such as anti-apoptosis, cell proliferation, autophagy, and senescence. Whole-body Bis-knockout (KO) mice exhibit early lethality accompanied by a
Externí odkaz:
https://doaj.org/article/7f2712da140043ec96f3a364f2daccbd
Autor:
Jin Won Kim, Sun Ah Nam, Jawoon Yi, Jae Yun Kim, Jong Young Lee, Seo‐Yeon Park, Tugce Sen, Yoo‐mi Choi, Jae Yeon Lee, Hong Lim Kim, Hyung Wook Kim, Jiwhan Park, Dong‐Woo Cho, Yong Kyun Kim
Publikováno v:
Advanced Science, Vol 9, Iss 15, Pp n/a-n/a (2022)
Abstract Kidney organoids derived from human pluripotent stem cells (hPSCs) have extensive potential for disease modelling and regenerative medicine. However, the limited vascularization and immaturity of kidney organoids have been still remained to
Externí odkaz:
https://doaj.org/article/373f81733f7445ebb9d81ff268d0ae7f
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-16 (2019)
Abstract Background Osteopontin (OPN, SPP1) is upregulated in response to acute brain injury, and based on its immunoreactivity, two distinct forms have been identified: intracellular OPN within brain macrophages and small granular OPN, identified as
Externí odkaz:
https://doaj.org/article/21cc3440ba5e4526ab0e3eac029c28a1
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Perivascular cells expressing platelet-derived growth factor receptor beta (PDGFR-β) have recently been implicated in fibrotic scar formation after acute brain injury, but their precise identity and detailed morphological characteristics remain elus
Externí odkaz:
https://doaj.org/article/3a718bd153de455dab8dbca471b0a4e2
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Glucose-regulated protein (GRP78) or BiP, a 78-kDa chaperone protein located in the endoplasmic reticulum (ER), has recently been reported to be involved in the neuroglial response to ischemia-induced ER stress. The present study was designed to stud
Externí odkaz:
https://doaj.org/article/79a2b78c9b094f8e9b3f7314f00f680d