Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hong Laura Lu"'
Publikováno v:
Model Assisted Statistics and Applications. 5:151-157
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38bb14c8b0f59fb7e0d19c115326141c
https://doi.org/10.3233/mas-2010-0156
https://doi.org/10.3233/mas-2010-0156
Publikováno v:
Journal of Clinical Oncology. 27:2874-2880
Several challenging and often controversial issues arise in oncology trials with the use of the end point progression-free survival (PFS), defined to be the time to detection of progressive disease or death. While this end point does not directly mea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92aa285ecd864624f7c264da3e00ac4b
https://doi.org/10.1200/jco.2008.20.4107
https://doi.org/10.1200/jco.2008.20.4107
Autor:
Hong Laura Lu, Mohammad F. Huque
Publikováno v:
Biometrical Journal. 43:909-923
Several independent clinical trials are usually conducted to demonstrate and support the evidence of the efficacy of a new drug. When not all the trials demonstrate a treatment effect because of a lack of statistical significant finding, the sponsor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43ecd2b0fd672c72cc4794491082a125
https://doi.org/10.1002/1521-4036(200111)43:7<909::aid-bimj909>3.0.co
https://doi.org/10.1002/1521-4036(200111)43:7<909::aid-bimj909>3.0.co
Autor:
Kallappa Koti, Hong Laura Lu, Haojin Zhou, Yuan Li Shen, Mei Jin, Jenny J. Zhang, Mark Rothmann, Kyung Yul Lee
Publikováno v:
Journal of biopharmaceutical statistics. 23(5)
The intent-to-treat principle, grouping subjects as they were randomized and following all subjects to the endpoint or the end of study, allows valid statistical comparisons. Progression-free survival (PFS) has been used as a decision-making endpoint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4fa45578597f7760cb1c8de05b383dc
https://pubmed.ncbi.nlm.nih.gov/23957518
https://pubmed.ncbi.nlm.nih.gov/23957518
Publikováno v:
Journal of biopharmaceutical statistics. 19(6)
The intent-to-treat principle requires analyses according to the treatment groups to which patients were randomized and that patients be followed to the occurrence of the endpoint or the end of study. This provides unbiased comparisons with valid p v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48fd137d2da323d912b4351d07a9aca8
https://pubmed.ncbi.nlm.nih.gov/20183465
https://pubmed.ncbi.nlm.nih.gov/20183465
Publikováno v:
Model Assisted Statistics & Applications; 2010, Vol. 5 Issue 3, p151-157, 7p, 6 Charts