Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Hong Jo Lee"'
Characterization of transcriptional enhancers in the chicken genome using CRISPR-mediated activation
Publikováno v:
Frontiers in Genome Editing, Vol 5 (2023)
DNA regulatory elements intricately control when, where, and how genes are activated. Therefore, understanding the function of these elements could unveil the complexity of the genetic regulation network. Genome-wide significant variants are predomin
Externí odkaz:
https://doaj.org/article/8e8890569db54568bda7c6a1d962b0f6
Autor:
Deivendran Rengaraj, Dong Gon Cha, Hong Jo Lee, Kyung Youn Lee, Yoon Ha Choi, Kyung Min Jung, Young Min Kim, Hee Jung Choi, Hyeon Jeong Choi, Eunhui Yoo, Seung Je Woo, Jin Se Park, Kyung Je Park, Jong Kyoung Kim, Jae Yong Han
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 1654-1669 (2022)
Avian germ cells can be distinguished by certain characteristics during development. On the basis of these characteristics, germ cells can be used for germline transmission. However, the dynamic transcriptional landscape of avian germ cells during de
Externí odkaz:
https://doaj.org/article/cab8ac022f374cd9a9944c5d068cf9dc
Autor:
Kelly Chungu, Young Hyun Park, Seung Je Woo, Su Bin Lee, Deivendran Rengaraj, Hong Jo Lee, Jae Yong Han
Publikováno v:
BMC Biotechnology, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background The initial step of influenza infection is binding of the virus to specific sialic acid receptors expressed by host cells. This is followed by cell entry via endocytosis. Cleavage of the influenza virus hemagglutinin (HA) protein
Externí odkaz:
https://doaj.org/article/d00233d020b54ef4b9f3aed93445df98
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 10, Iss 1, Pp 1-14 (2019)
Abstract Background Previously, we showed that targeted disruption of viral receptor genes in avian leukosis virus (ALV) subgroups using clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9))-based geno
Externí odkaz:
https://doaj.org/article/3cf31a10c782450c8e938d0b0a04bfff
Autor:
Hong Jo Lee, Kyung Youn Lee, Young Hyun Park, Hee Jung Choi, Yongxiu Yao, Venugopal Nair, Jae Yong Han
Publikováno v:
Veterinary Research, Vol 48, Iss 1, Pp 1-10 (2017)
Abstract Avian leukosis virus (ALV) is a retrovirus that causes tumors in avian species, and its vertical and horizontal transmission in poultry flocks results in enormous economic losses. Despite the discovery of specific host receptors, there have
Externí odkaz:
https://doaj.org/article/6cc8a1b34a9846cf91c0cddb1a4cec8e
Publikováno v:
Genes; Volume 14; Issue 4; Pages: 906
Engineering of clustered regularly interspaced short palindromic repeats (CRISPR) and the CRISPR-associated protein 9 (Cas9) system has enabled versatile applications of CRISPR beyond targeted DNA cleavage. Combination of nuclease-deactivated Cas9 (d
Autor:
Jae Yong Han, Hong Jo Lee
Publikováno v:
Methods in Molecular Biology ISBN: 9781071630150
Methods in Molecular Biology ISBN: 9781493971275
Methods in Molecular Biology ISBN: 9781493971275
Rapid development of genome editing technology has facilitated the studies on exploring specific gene functions and establishment of model animals. In livestock, the technology has contributed to create high value in industry fields, e.g., enhancing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eda9c1043585ef93a8d6c85fff3cab6c
https://doi.org/10.1007/978-1-0716-3016-7_23
https://doi.org/10.1007/978-1-0716-3016-7_23
Autor:
Young-Min Kim, Humphrey H.-C. Yao, Minseok Seo, Hong Jo Lee, Soo Taek Han, Kyung Je Park, Kyung Min Jung, Kyu Hyuk Lee, Hee Jung Choi, Jin Se Park, Kyung Youn Lee, Jae Yong Han, Deivendran Rengaraj
Publikováno v:
FASEB J
Compared with the well-described XY sex determination system in mammals, the avian ZW sex determination system is poorly understood. Knockdown and overexpression studies identified doublesex and mab-3 related transcription factor 1 (DMRT1) as the tes
Autor:
Young Hyun Park, Kyung Je Park, Jin Se Park, Deivendran Rengaraj, Jong Won Yoon, Young-Min Kim, Kyung Youn Lee, Hong Jo Lee, Kyung Min Jung, Young Hwang, Jae Yong Han
Publikováno v:
The FASEB Journal. 33:8519-8529
Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated protein 9 (Cas9) have facilitated the production of genome-edited animals for use as models. Because of their unique developmental system, avian species offer ma
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 10, Iss 1, Pp 1-14 (2019)
Journal of Animal Science and Biotechnology
Journal of Animal Science and Biotechnology
Background Previously, we showed that targeted disruption of viral receptor genes in avian leukosis virus (ALV) subgroups using clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9))-based genome editin