Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Hong Jie Zhu"'
Autor:
Hong Jie Zhu, Bo Zhang, Wanqing Wei, Shuang He Liu, Lang Xiang, Jiapeng Zhu, Rui Hua Jiao, Yasuhiro Igarashi, Ghader Bashiri, Yong Liang, Ren Xiang Tan, Hui Ming Ge
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Macrocyclization is an important process in bioactive natural product synthesis. Here, the authors report on the study of a macrocyclic ring constructing enzyme in the biosynthesis of alchivemycin A and using gene deletion, biochemical assays and iso
Externí odkaz:
https://doaj.org/article/c4b5a7495b704b4bbee8ca1abd98b0d5
Autor:
Kai Biao Wang, Wen Wang, Bo Zhang, Xin Wang, Yu Chen, Hong Jie Zhu, Yong Liang, Ren Xiang Tan, Hui Ming Ge
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Streptoseomycin is a potent antibiotic that contains a pentacyclic 5/14/10/6/6 ring system. Here, the authors report the enzymatic and non-enzymatic steps of the downstream modification of streptoseomycin biosynthesis and show a [6 + 4]-cycloaddition
Externí odkaz:
https://doaj.org/article/7246c7166a5548fca61b1e86049ac423
Publikováno v:
Natural Products and Bioprospecting
Natural Products and Bioprospecting, Vol 11, Iss 1, Pp 51-62 (2020)
Natural Products and Bioprospecting, Vol 11, Iss 1, Pp 51-62 (2020)
Abstract Ten neolignans or norlignans (1–10) including eight new compounds were isolated from the whole bodies of Polyphaga plancyi Bolivar. Their structures were identified by spectroscopic data. Compounds 3, 4, 8, and 9 are racemates indicated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a72a5801901a586b8277b89f9bdffcd
http://europepmc.org/articles/PMC7933325
http://europepmc.org/articles/PMC7933325
Publikováno v:
Tetrahedron. 75:1029-1033
The insect Blaps japanensis have been used as an ethnomedicine in China for the treatment of several disorders such as cancer and inflammation. Our investigation with this insect led to the isolation of eight new and two known phenolic compounds. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15a325da4e3f178bd43a0cfbeb288a59
https://doi.org/10.1016/j.tet.2018.12.015
https://doi.org/10.1016/j.tet.2018.12.015
Autor:
Xuan Zhang, Ren-Xiang Tan, Zhen Zhen Zhou, Hong Jie Zhu, Rui Hua Jiao, Hui Ming Ge, Li Ping Lin
Publikováno v:
Chemical Science. 10:73-82
Polyketide-polyketide hybrids are unique natural products with promising bioactivity, but the hybridization processes remain poorly understood. Herein, we present that the biosynthetic pathways of two immunosuppressants, dalmanol A and acetodalmanol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9825430d7b5fa2d35e1d853dad0956e3
https://doi.org/10.1039/c8sc03697g
https://doi.org/10.1039/c8sc03697g
Autor:
Yasuhiro Igarashi, Ren-Xiang Tan, Wen Wang, Lan Wang, Shuang He Liu, Hong Jie Zhu, Bo Zhang, Hui Ming Ge, Ghader Bashiri
Publikováno v:
Journal of the American Chemical Society. 143(12)
Redox enzymes play a critical role in transforming nascent scaffolds into structurally complex and biologically active natural products. Alchivemycin A (AVM, 1) is a highly oxidized polycyclic compound with potent antimicrobial activity and features
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d180e647cc25adc61ff7bd05e0fae48f
https://pubmed.ncbi.nlm.nih.gov/33736434
https://pubmed.ncbi.nlm.nih.gov/33736434
Autor:
Hong Jie Zhu, Kai Biao Wang, Wen Wang, Ren-Xiang Tan, Bo Zhang, Yong Liang, Yu Chen, Hui Ming Ge, Xin Wang
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Streptoseomycin (STM, 1) is a bacterial macrolactone that has a unique 5/14/10/6/6-pentacyclic ring with an ether bridge. We have previously identified the biosynthetic gene cluster for 1 and characterized StmD as [6 + 4]- and [4 + 2]-bispericyclase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e1d7d814cf13ac0e8d3543c3fa9c6a5
https://pubmed.ncbi.nlm.nih.gov/33828077
https://pubmed.ncbi.nlm.nih.gov/33828077
Publikováno v:
Bioorganic chemistry. 102
Pipajiains H-J (1-3), three new phenolic derivatives with an unusual sulfone group, pipajiamides A-C (4-6), three new amide derivatives, pipajiaine A (7), one new imidazole analogue, and pipajiaine B (8), a pair of new pyrrolidine derivatives, along
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bc5da1a582d54a796257ba97195ed6f
https://pubmed.ncbi.nlm.nih.gov/32688114
https://pubmed.ncbi.nlm.nih.gov/32688114
Autor:
Yong-Sheng Xiao, Ren-Xiang Tan, Li-Yun Shi, Hong-Jie Zhu, Cheng-Long Yang, Nan Jiang, Zhen-Zhen Zhou, Yan-Jun Liu, Rui-Hua Jiao, Hui-Ming Ge
Publikováno v:
Chinese journal of natural medicines. 17(5)
Replacement of the native promoter of theglobal regulator LaeA-like gene of Daldinia eschscholzii by a strong gpdA promoter led to the generation of two novel cyclopentenone metabolites, named dalestones A and B, whose structures were assigned by a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc2f73b098dcbe3d8bb67b5914771c7
https://pubmed.ncbi.nlm.nih.gov/31171274
https://pubmed.ncbi.nlm.nih.gov/31171274
Publikováno v:
Bioorganic Chemistry. 104:104258
Five new nitrogen-containing compounds (1-3, 5, and 6), two compounds which was firstly isolated from natural origin (7 and 10), along with six known ones, were isolated from the ethanol extract of the whole bodies of Polyphaga plancyi. The structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166f6357adfb17928970190cde748fd3
https://doi.org/10.1016/j.bioorg.2020.104258
https://doi.org/10.1016/j.bioorg.2020.104258