Mechanistic evaluation of the initial burst release of leuprolide from spray-dried PLGA microspheres.

Autor: Schutzman R; Department of Pharmaceutical Sciences, The Biointerfaces Institute, University of Michigan, 2800 Plymouth Rd., Ann Arbor, MI 48109, USA., Shi NQ; Department of Pharmaceutical Sciences, The Biointerfaces Institute, University of Michigan, 2800 Plymouth Rd., Ann Arbor, MI 48109, USA; School of Pharmacy, Jilin Medical University, Jilin 132013, Jilin Province, China., Olsen KF; Department of Pharmaceutical Sciences, The Biointerfaces Institute, University of Michigan, 2800 Plymouth Rd., Ann Arbor, MI 48109, USA., Ackermann R; Department of Pharmaceutical Sciences, The Biointerfaces Institute, University of Michigan, 2800 Plymouth Rd., Ann Arbor, MI 48109, USA., Tang J; Department of Pharmaceutical Sciences, The Biointerfaces Institute, University of Michigan, 2800 Plymouth Rd., Ann Arbor, MI 48109, USA., Liu YY; Department of Pharmaceutical Sciences, The Biointerfaces Institute, University of Michigan, 2800 Plymouth Rd., Ann Arbor, MI 48109, USA., Hong JKY; Department of Pharmaceutical Sciences, The Biointerfaces Institute, University of Michigan, 2800 Plymouth Rd., Ann Arbor, MI 48109, USA., Wang Y; Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, 10903 New Hampshire Ave., Silver Spring, MD 20993, USA., Qin B; Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, 10903 New Hampshire Ave., Silver Spring, MD 20993, USA., Schwendeman A; Department of Pharmaceutical Sciences, The Biointerfaces Institute, University of Michigan, 2800 Plymouth Rd., Ann Arbor, MI 48109, USA., Schwendeman SP; Department of Pharmaceutical Sciences, The Biointerfaces Institute, University of Michigan, 2800 Plymouth Rd., Ann Arbor, MI 48109, USA; Department of Biomedical Engineering, University of Michigan, 2800 Plymouth Rd., Ann Arbor, MI 48109, USA. Electronic address: schwende@med.umich.edu.

Publikováno v: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2023 Sep; Vol. 361, pp. 297-313. Date of Electronic Publication: 2023 Aug 10.

Efficient aqueous remote loading of peptides in poly(lactic-co-glycolic acid).

Autor: Giles MB; Department of Pharmaceutical Sciences and the Biointerfaces Institute, University of Michigan, North Campus Research Complex, 2800 Plymouth Road, Ann Arbor, MI, 48109, USA., Hong JKY; Department of Pharmaceutical Sciences and the Biointerfaces Institute, University of Michigan, North Campus Research Complex, 2800 Plymouth Road, Ann Arbor, MI, 48109, USA., Liu Y; Department of Pharmaceutical Sciences and the Biointerfaces Institute, University of Michigan, North Campus Research Complex, 2800 Plymouth Road, Ann Arbor, MI, 48109, USA., Tang J; Department of Pharmaceutical Sciences and the Biointerfaces Institute, University of Michigan, North Campus Research Complex, 2800 Plymouth Road, Ann Arbor, MI, 48109, USA., Li T; Department of Pharmaceutical Sciences and the Biointerfaces Institute, University of Michigan, North Campus Research Complex, 2800 Plymouth Road, Ann Arbor, MI, 48109, USA., Beig A; Department of Pharmaceutical Sciences and the Biointerfaces Institute, University of Michigan, North Campus Research Complex, 2800 Plymouth Road, Ann Arbor, MI, 48109, USA., Schwendeman A; Department of Pharmaceutical Sciences and the Biointerfaces Institute, University of Michigan, North Campus Research Complex, 2800 Plymouth Road, Ann Arbor, MI, 48109, USA., Schwendeman SP; Department of Pharmaceutical Sciences and the Biointerfaces Institute, University of Michigan, North Campus Research Complex, 2800 Plymouth Road, Ann Arbor, MI, 48109, USA. schwende@umich.edu.; Department of Biomedical Engineering, University of Michigan, 2200 Bonisteel Blvd, Ann Arbor, MI, 48109, USA. schwende@umich.edu.

Publikováno v: Nature communications [Nat Commun] 2022 Jun 08; Vol. 13 (1), pp. 3282. Date of Electronic Publication: 2022 Jun 08.

Monoclonal Antibody Aggregation Associated with Free Radical Induced Oxidation.

Autor: Zheng K; Pharmaceutical Development, Genentech, South San Francisco, CA 94080, USA., Ren D; Oceanside Pharmaceutical Technical Development, Genentech, Oceanside, CA 92056, USA., Wang YJ; Pharmaceutical Development, Genentech, South San Francisco, CA 94080, USA., Lilyestrom W; Pharmaceutical Development, Genentech, South San Francisco, CA 94080, USA., Scherer T; Pharmaceutical Development, Genentech, South San Francisco, CA 94080, USA., Hong JKY; Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI 48109, USA., Ji JA; Pharmaceutical Development, Genentech, South San Francisco, CA 94080, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2021 Apr 12; Vol. 22 (8). Date of Electronic Publication: 2021 Apr 12.

Physical-Chemical Characterization of Octreotide Encapsulated in Commercial Glucose-Star PLGA Microspheres.

Autor: Beig A; Department of Pharmaceutical Sciences and the Biointerfaces Institute, University of Michigan, 2800 Plymouth Road, Ann Arbor, Michigan 48109, United States., Feng L; Department of Pharmaceutical Sciences and the Biointerfaces Institute, University of Michigan, 2800 Plymouth Road, Ann Arbor, Michigan 48109, United States., Walker J; Department of Pharmaceutical Sciences and the Biointerfaces Institute, University of Michigan, 2800 Plymouth Road, Ann Arbor, Michigan 48109, United States., Ackermann R; Department of Pharmaceutical Sciences and the Biointerfaces Institute, University of Michigan, 2800 Plymouth Road, Ann Arbor, Michigan 48109, United States., Hong JKY; Department of Pharmaceutical Sciences and the Biointerfaces Institute, University of Michigan, 2800 Plymouth Road, Ann Arbor, Michigan 48109, United States., Li T; Department of Pharmaceutical Sciences and the Biointerfaces Institute, University of Michigan, 2800 Plymouth Road, Ann Arbor, Michigan 48109, United States., Wang Y; Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, Massachusetts 20993, United States., Qin B; Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, Massachusetts 20993, United States., Schwendeman SP; Department of Pharmaceutical Sciences and the Biointerfaces Institute, University of Michigan, 2800 Plymouth Road, Ann Arbor, Michigan 48109, United States.; Department of Biomedical Engineering, University of Michigan, 2200 Bonisteel Blvd., Ann Arbor, Michigan 48109, United States.

Publikováno v: Molecular pharmaceutics [Mol Pharm] 2020 Nov 02; Vol. 17 (11), pp. 4141-4151. Date of Electronic Publication: 2020 Oct 19.

Microencapsulation of luteinizing hormone-releasing hormone agonist in poly (lactic-co-glycolic acid) microspheres by spray-drying.

Autor: Shi NQ; Department of Pharmaceutical Sciences, The Biointerfaces Institute, University of Michigan, 2800 Plymouth Rd., Ann Arbor, MI 48109, USA; School of Pharmacy, Jilin Medical University, Jilin 132013, Jilin Province, China., Zhou J; Department of Pharmaceutical Sciences, The Biointerfaces Institute, University of Michigan, 2800 Plymouth Rd., Ann Arbor, MI 48109, USA., Walker J; Department of Pharmaceutical Sciences, The Biointerfaces Institute, University of Michigan, 2800 Plymouth Rd., Ann Arbor, MI 48109, USA., Li L; School of Pharmaceutical Science, Liaoning University, Jilin 132013, Jilin Province, China., Hong JKY; Department of Pharmaceutical Sciences, The Biointerfaces Institute, University of Michigan, 2800 Plymouth Rd., Ann Arbor, MI 48109, USA., Olsen KF; Department of Pharmaceutical Sciences, The Biointerfaces Institute, University of Michigan, 2800 Plymouth Rd., Ann Arbor, MI 48109, USA., Tang J; Department of Pharmaceutical Sciences, The Biointerfaces Institute, University of Michigan, 2800 Plymouth Rd., Ann Arbor, MI 48109, USA., Ackermann R; Department of Pharmaceutical Sciences, The Biointerfaces Institute, University of Michigan, 2800 Plymouth Rd., Ann Arbor, MI 48109, USA., Wang Y; Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, 10903 New Hampshire Ave., Silver Spring, MD 20993, USA., Qin B; Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, 10903 New Hampshire Ave., Silver Spring, MD 20993, USA., Schwendeman A; Department of Pharmaceutical Sciences, The Biointerfaces Institute, University of Michigan, 2800 Plymouth Rd., Ann Arbor, MI 48109, USA., Schwendeman SP; Department of Pharmaceutical Sciences, The Biointerfaces Institute, University of Michigan, 2800 Plymouth Rd., Ann Arbor, MI 48109, USA; Department of Biomedical Engineering, University of Michigan, 2800 Plymouth Rd., Ann Arbor, MI 48109, USA. Electronic address: schwende@med.umich.edu.

Publikováno v: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2020 May 10; Vol. 321, pp. 756-772. Date of Electronic Publication: 2020 Jan 11.