Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Hong Hua Yan"'
Autor:
Kyung Hee Jung, Mi Kwon Son, Hong Hua Yan, Zhenghuan Fang, Juyoung Kim, Soo Jung Kim, Jung Hee Park, Ji Eun Lee, Young‐Chan Yoon, Myeong Seong Seo, Beom Seok Han, Soyeon Ko, Young Ju Suh, Joo Han Lim, Don‐Haeng Lee, Ziqiang Teo, Jonathan Wei Kiat Wee, Nguan Soon Tan, Soon‐Sun Hong
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 8, Pp n/a-n/a (2020)
Abstract Pancreatitis is the inflammation of the pancreas. However, little is known about the genes associated with pancreatitis severity. Our microarray analysis of pancreatic tissues from mild and severe acute pancreatitis mice models identified an
Externí odkaz:
https://doaj.org/article/9ddcdb3fea6f4d339aa61f04fa2c5ca5
Autor:
Zhenghuan Fang, Kyung Hee Jung, Hong Hua Yan, Soo-Jung Kim, Marufa Rumman, Jung Hee Park, Boreum Han, Ji Eun Lee, Yeo wool Kang, Joo Han Lim, Soon Sun Hong
Publikováno v:
Cellular Physiology and Biochemistry, Vol 47, Iss 5, Pp 1751-1768 (2018)
Background/Aims: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignant tumors with poor prognosis. Conventional chemotherapies including gemcitabine have failed owing to weak response and side effects. Hence novel treatment regi
Externí odkaz:
https://doaj.org/article/74a9ddd7af924cf985b8ae59ad421ad8
Autor:
Juyoung Kim, Kyung Hee Jung, Hong Hua Yan, Min Ji Cheon, Sunmi Kang, Xing Jin, Sunghyouk Park, Myung Sook Oh, Soon-Sun Hong
Publikováno v:
BMC Complementary and Alternative Medicine, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Natural product is one of the most important sources of drugs used in pharmaceutical therapeutics. Artemisia capillaris has been traditionally used as a hepatoprotective and anti-inflammatory agent. In this study, we extracted an
Externí odkaz:
https://doaj.org/article/83a592aaa6e64916bc81ffd99ec7ef36
Autor:
Min Gyu Woo, Yong Sung Kim, Mi Kwon Son, Seung-Min Shin, Zhenghuan Fang, Kyung Hee Jung, Soon-Sun Hong, Young-Chan Yoon, Hong Hua Yan, Ji Eun Lee, Yeo Wool Kang, Jung Hee Park
Publikováno v:
Biomolecules & Therapeutics. 30:274-283
KRAS activating mutations, which are present in more than 90% of pancreatic cancers, drive tumor dependency on the RAS/mitogen-activated protein kinase (MAPK) and phosphoinositide 3-kinase (PI3K)/AKT signaling pathways. Therefore, combined targeting
Autor:
Jung Hee Park, Juyoung Kim, Mi Kwon Son, Soo Jung Kim, Hong Hua Yan, Ji Eun Lee, Zhenghuan Fang, Kyung Hee Jung, Soon-Sun Hong, Ju Han Lim
Publikováno v:
Cancer Letters. 519:185-198
Oncogenic KRASG12D induces neoplastic transformation of pancreatic acinar cells through acinar-to-ductal metaplasia (ADM) and pancreatic intraepithelial neoplasia (PanIN), and drives pancreatic ductal adenocarcinoma (PDAC). Angiopoietin-like 4 (ANGPT
Autor:
Hong Hua, Yan, Kyung Hee, Jung, Ji Eun, Lee, Mi Kwon, Son, Zhenghuan, Fang, Jung Hee, Park, Soo Jung, Kim, Ju Young, Kim, Ju Han, Lim, Soon-Sun, Hong
Publikováno v:
Cancer letters. 519
Oncogenic KRAS
Autor:
Shinmee Mah, Jung Hee Park, Kyung Hee Jung, Young-Chan Yoon, Soon-Sun Hong, Zhenghuan Fang, Soo Jung Kim, You-Sun Kim, Sungwoo Hong, Joo Han Lim, Ji Eun Lee, Hong Hua Yan
Publikováno v:
Cancer Letters. 444:94-104
Necroptosis is a form of regulated necrotic cell death mediated by receptor-interacting kinase 3 (RIP3). Recently, necroptosis has gained attention as a novel alternative therapy to target cancer cells. In this study, we screened several chemotherape
Autor:
Yong Sung Kim, Kyung Hee Jung, Soon-Sun Hong, Yeo Wool Kang, Seung-Min Shin, Min Ji Cheon, Soo Jung Kim, Min Gyu Woo, Mi Kwon Son, Boreum Han, Hong Hua Yan, Jung Hee Park, Zhenghuan Fang, Joo Han Lim, Ji Eun Lee
Publikováno v:
Cancer Letters. 438:174-186
Pancreatic cancer exhibits an oncogenic KRAS mutation rate of ∼90%. Despite research and drug development efforts focused on KRAS, no targeted therapy has been clinically approved for the treatment of pancreatic cancer with KRAS mutation. Also, the
Autor:
Min Gyu Woo, Soo Jung Kim, Ji Eun Lee, Zhenghuan Fang, Yong Sung Kim, Seung-Min Shin, Myung Sung Seo, Min Ji Cheon, Kyung Hee Jung, Soon-Sun Hong, Mi Kwon Son, Jung Hee Park, Yeo Wool Kang, Young-Chan Yoon, Hong Hua Yan, Joo Han Lim, Boreum Han, Ji-Sun Kim
Publikováno v:
Cancer letters. 507
KRAS mutation is associated with the progression and growth of pancreatic cancer and contributes to chemo-resistance, which poses a significant clinical challenge in pancreatic cancer. Here, we developed a RT22-ep59 antibody (Ab) that directly target
Autor:
Ji Eun Lee, Young-Chan Yoon, Zhenghuan Fang, Don Haeng Lee, Kyung Hee Jung, Soon-Sun Hong, Nguan Soon Tan, Soo Jung Kim, Juyoung Kim, Ziqiang Teo, Jung Hee Park, Joo Han Lim, Jonathan Wei Kiat Wee, Soyeon Ko, Myeong Seong Seo, Beom Seok Han, Young Ju Suh, Mi Kwon Son, Hong Hua Yan
Publikováno v:
Publons
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 12, Iss 8, Pp n/a-n/a (2020)
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 12, Iss 8, Pp n/a-n/a (2020)
Pancreatitis is the inflammation of the pancreas. However, little is known about the genes associated with pancreatitis severity. Our microarray analysis of pancreatic tissues from mild and severe acute pancreatitis mice models identified angiopoieti