Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Hong‑Gang Pang"'
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 10, Pp 1726-1733 (2019)
The role of vascular endothelial growth factor A in platelet adhesion in cerebral microvessels in the early stage of subarachnoid hemorrhage remains unclear. In this study, the endovascular puncture method was used to produce a rat model of subarachn
Externí odkaz:
https://doaj.org/article/950eccb575794db495899a2e07d7fc75
Publikováno v:
Neural Regeneration Research, Vol 11, Iss 6, Pp 944-950 (2016)
Rosiglitazone up-regulates caveolin-1 levels and has neuroprotective effects in both chronic and acute brain injury. Therefore, we postulated that rosiglitazone may ameliorate diffuse axonal injury via its ability to up-regulate caveolin-1, inhibit e
Externí odkaz:
https://doaj.org/article/124883527abb4db5ba1310e81021e882
Publikováno v:
Neuroreport
Diffuse axonal injury (DAI) accounts for more than 50% of all traumatic brain injury. In response to the mechanical damage associated with DAI, the abnormal proteins produced in the neurons and axons, namely, β-APP and p-tau, induce endoplasmic reti
Publikováno v:
BMC Medical Genetics
BMC Medical Genetics, Vol 20, Iss 1, Pp 1-9 (2019)
BMC Medical Genetics, Vol 20, Iss 1, Pp 1-9 (2019)
Background Ischemic stroke (IS) is a serious cardiovascular disease and is associated with several single nucleotide polymorphisms (SNPs). However, the role of Cytochrome P450 family 4 subfamily F member 2 (CYP4F2) gene in IS remains unknown. Our stu
Autor:
Jinning Song, Hong-Gang Pang, Ming Zhang, Yahui Zhao, Yonglin Zhao, Xudong Ma, Junjie Zhao, Tingqin Huang, Jiaxi Li
Publikováno v:
Mediators of Inflammation
Mediators of Inflammation, Vol 2016 (2016)
Mediators of Inflammation, Vol 2016 (2016)
Increasing evidence suggests that secondary injury after diffuse axonal injury (DAI) damages more axons than the initial insult, but the underlying mechanisms of this phenomenon are not fully understood. Recent studies show that toll-like receptor 4
Publikováno v:
Journal of the Neurological Sciences. 350:84-89
Receptor-associated protein (RAP) is a receptor antagonist that inhibits ligand interactions with the receptors that belong to the low density lipoprotein receptor gene family. The low-density lipoprotein receptor-related protein 1 (LRP1) has a cruci
Autor:
Ji-Yang An, Ming Zhang, Jinning Song, Dan-Dong Li, Peng Sun, Li-Li Zhou, Hong-Gang Pang, Yu Li
Publikováno v:
Acta Neurochirurgica. 157:781-792
AMP-activated protein kinase (AMPK) is a key metabolic and stress sensor/effector. Few investigations have been performed to study the role of AMPK in subarachnoid hemorrhage (SAH)-induced early brain injury (EBI). This study was undertaken to invest
Autor:
Yonglin Zhao, Jinning Song, Peng Sun, Bin-fei Zhang, Ming Zhang, Huan Huang, Xudong Ma, Dan-Dong Li, Hong-Gang Pang
Publikováno v:
Cell Biology International. 39:788-798
A rapid increase in matrix metalloproteinase-9 (MMP-9) expression by stimulated leukocytes is common in many diseases. Recent evidence suggests that the beneficial effects of statins are mediated in part by the suppression of MMP-9 release. In this s
Autor:
Peng Sun, Dan-Dong Li, Yu Li, Xudong Ma, Hong-Gang Pang, Yonglin Zhao, Jinning Song, Tingqin Huang, Bin-fei Zhang, Zun-wei Liu
Publikováno v:
Neurochemical Research. 40:591-599
Cerebral inflammation plays a crucial role in early brain injury (EBI) after subarachnoid hemorrhage (SAH). This study investigated the effects of c-Jun N-terminal kinase (JNK) inhibitor SP600125, acetylcholine (Ach), etanercept, and anti-TNF-α on c
Autor:
Yonglin Zhao, Bo Wang, Jinning Song, Ming Zhang, Junjie Zhao, Jiaxi Li, Xudong Ma, Hong-Gang Pang, Tingqin Huang, Yahui Zhao
Publikováno v:
Mediators of Inflammation
Mediators of Inflammation, Vol 2017 (2017)
Mediators of Inflammation, Vol 2017 (2017)
Treatment of diffuse axonal injury (DAI) remains challenging in clinical practice due to the unclear pathophysiological mechanism. Uncontrolled, excessive inflammation is one of the most recognized mechanisms that contribute to the secondary injury a