2-Aminoimidazole Analogs Target PhoP Altering DNA Binding Activity and Affect Outer Membrane Stability in Gram-Negative Bacteria.

Autor: Zeczycki TN; Department of Biochemistry and Molecular Biology, Brody School of Medicine, East Carolina University, Greenville, North Carolina27834, United States., Milton ME; Department of Biochemistry and Molecular Biology, Brody School of Medicine, East Carolina University, Greenville, North Carolina27834, United States., Jung D; Agile Sciences Inc., 617 Hutton Street, Raleigh, North Carolina27606, United States., Thompson RJ; Department of Biochemistry and Molecular Biology, Brody School of Medicine, East Carolina University, Greenville, North Carolina27834, United States., Jaimes FE; Department of Biochemistry and Molecular Biology, Brody School of Medicine, East Carolina University, Greenville, North Carolina27834, United States., Hondros AD; Department of Biochemistry and Molecular Biology, Brody School of Medicine, East Carolina University, Greenville, North Carolina27834, United States., Palethorpe S; Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, North Carolina27834, United States., Melander C; Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana46556, United States., Cavanagh J; Department of Biochemistry and Molecular Biology, Brody School of Medicine, East Carolina University, Greenville, North Carolina27834, United States.

Publikováno v: Biochemistry [Biochemistry] 2022 Dec 20; Vol. 61 (24), pp. 2948-2960. Date of Electronic Publication: 2022 Dec 01.