Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Additional file 12 of Distinct cell type-specific protein signatures in GRN and MAPT genetic subtypes of frontotemporal dementia

Autor: Miedema, Suzanne S. M., Mol, Merel O., Koopmans, Frank T. W., Hondius, David C., van Nierop, Pim, Menden, Kevin, de Veij Mestdagh, Christina F., van Rooij, Jeroen, Ganz, Andrea B., Paliukhovich, Iryna, Melhem, Shamiram, Li, Ka Wan, Holstege, Henne, Rizzu, Patrizia, van Kesteren, Ronald E., van Swieten, John C., Heutink, Peter, Smit, August B.

Additional file 12 Raw images of OXPHOS and PLP1 immunoblotting experiments. (A) Total protein load for each sample on the gels used in the OXPHOS immunoblotting experiments (Bio-Rad gel images). Specific antibody signal values on the corresponding b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c494c01086d6d436a709532e41328e2

A Laser Microdissection-Liquid Chromatography-Tandem Mass Spectrometry Workflow for Post-mortem Analysis of Brain Tissue

Autor: Hondius, David C, Hoozemans, Jeroen J M, Rozemuller, Annemieke J M, Li, Ka Wan, Smit, August B

Publikováno v: Hondius, D C, Hoozemans, J J M, Rozemuller, A J M, Li, K W & Smit, A B 2018, ' A Laser Microdissection-Liquid Chromatography-Tandem Mass Spectrometry Workflow for Post-mortem Analysis of Brain Tissue ', Methods in Molecular Biology, vol. 1723, pp. 371-383 . https://doi.org/10.1007/978-1-4939-7558-7_21
Methods in Molecular Biology, 1723, 371-383. Humana Press

Improved speed and sensitivity of mass spectrometry allow the simultaneous quantification of high numbers of proteins from increasingly smaller quantities of tissue sample. Quantitative data of the proteome is highly valuable for providing unbiased i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6a114d5348995358d5464f54bb8675a5
https://research.vumc.nl/en/publications/8bdf25c5-9459-4470-a9e2-40cf162c15d5

Laser microdissection for spatial proteomics of postmortem brain tissue

Autor: Hondius, David C., Hoozemans, Jeroen J.M., Rozemuller, Annemieke J.M., Smit, August B., Li, Ka Wan

Publikováno v: Neuromethods, 146, 43. Humana Press Inc.
Neuromethods, 43-53
STARTPAGE=43;ENDPAGE=53;TITLE=Neuromethods
Hondius, D C, Hoozemans, J J M, Rozemuller, A J M & Smit, A B 2019, Laser microdissection for spatial proteomics of postmortem brain tissue . in Neuromethods . Neuromethods, vol. 146, Humana Press Inc., pp. 43-53 . https://doi.org/10.1007/978-1-4939-9662-9_4
Hondius, D C, Hoozemans, J J M, Rozemuller, A J M & Smit, A B 2019, Laser microdissection for spatial proteomics of postmortem brain tissue . in K W Li (ed.), Neuroproteomics . 2nd edn, Neuromethods, vol. 146, Humana Press Inc, New York, NY, pp. 43-53 . https://doi.org/10.1007/978-1-4939-9662-9_4
Neuroproteomics, 43-53
ISSUE=2nd;STARTPAGE=43;ENDPAGE=53;TITLE=Neuroproteomics
Neuromethods ISBN: 9781493996612

Quantitative data of the proteome is highly valuable for providing unbiased information on protein expression changes related to disease or identifying related biomarkers. In brain diseases the affected area can be small and pathogenic events can be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d0fcac3a088cc4a2f831d97e5efc8f
https://hdl.handle.net/1874/391346