Výsledky vyhledávání - "Hondamuni I. De Silva"

Characterization and cytoprotective properties of Sargassum natans fucoidan against urban aerosol-induced keratinocyte damage

Autor: C. M. Nanayakkara, D.T.U. Abeytunga, Ilekuttige Priyan Shanura Fernando, Kalu Kapuge Asanka Sanjeewa, A.P.J.P. Vaas, WonWoo Lee, Hyo Geun Lee, Hyun-Soo Kim, You-Jin Jeon, Dae Sung Lee, Hondamuni I. De Silva

Publikováno v: International Journal of Biological Macromolecules. 159:773-781

The escalation of fine particulate matter (PM) air pollution has recently become a global concern. Evidence is fast accumulating on PM exposure-related skin damage. The present study explored the therapeutic potentials of fucoidan purified from Sarga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9680dd6d26406c2958c63d665991756
https://doi.org/10.1016/j.ijbiomac.2020.05.132

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Fucoidan Purified from Sargassum polycystum Induces Apoptosis through Mitochondria-Mediated Pathway in HL-60 and MCF-7 Cells

Autor: Hyo Geun Lee, C. M. Nanayakkara, Hondamuni I. De Silva, You-Jin Jeon, Jung-Suck Lee, Ilekuttige Priyan Shanura Fernando, Hyun-Soo Kim, D.T.U. Abeytunga, Kalu Kapuge Asanka Sanjeewa, A.P.J.P. Vaas, Dae Sung Lee

Publikováno v: Marine Drugs
Volume 18
Issue 4
Marine Drugs, Vol 18, Iss 196, p 196 (2020)

Fucoidans are biocompatible, heterogeneous, and fucose rich sulfated polysaccharides biosynthesized in brown algae, which are renowned for their broad-spectrum biofunctional properties. As a continuation of our preliminary screening studies, the pres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90e369a9c3dc7af120ae80485f390a35

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Synthesis of Functionalized Fused-Ring Heterocycles from Tautomers of 2-(Thiazole, Oxazole, Benzothiazole, and Benzoxazole)-1-phenylethenols and 1,3-Diacid Chlorides or N-(Chlorocarbonyl) Isocyanate

Autor: Charles U. Pittman, William P. Henry, Sabornie Chatterjee, Hondamuni I. De Silva

Publikováno v: Synthesis. 44:3453-3464

2-Methylthiazole, 2,4,5-trimethylthiazole, 2,4,5-trimethyloxazole, 2-methylbenzothiazole, and 2-methylbenzoxazole were each reacted with benzoyl chloride in acetonitrile–triethylamine to generate (Z)-2-(heterocyclic)-1-phenylvinyl benzoates. Base h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f2f1da8fa28af222c9b80601e39ae10b
https://doi.org/10.1055/s-0032-1316800

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Reactions of Keto–Enol Tautomers of 2-Thiazolyl-, 2-Oxazolyl-, 2-Benzoxazolyl-, or 2-Benzothiazolyl-1-phenylethenols with α,β-Alkynyl Esters: Syntheses of Highly Functionalized Fused-Ring Heterocycles

Autor: Hondamuni I. De Silva, Charles U. Pittman, William P. Henry

Publikováno v: Synthesis. 44:3337-3352

2-Methyl-1,3-thiazole, 2,4-dimethyl-1,3-thiazole, 2,4,5-trimethyl-1,3-thiazole, 2,4,5-trimethyl-1,3-oxazole, 2-methyl-1,3-benzoxazole and 2-methyl-1,3-benzothiazole were each treated with benzoyl chloride in acetonitrile containing triethylamine to g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::66b96373ae86b70d449028d016b6d99e
https://doi.org/10.1055/s-0032-1316790

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Ring size and substituent steric effects in cyclic ketene-N,O/S-acetal trifluoroacetylations

Autor: Hondamuni I. De Silva, Yingquan Song, William P. Henry, Charles U. Pittman

Publikováno v: Tetrahedron Letters. 53:2965-2970

Trifluoroacetylations of cyclic ketene-N,O/S-acetals exhibit a ring size effect. The five-membered rings 2,4,4-trimethyl-2-oxazoline, 2-methyl-2-oxazoline, and 2-methyl-2-thiazoline, each form cyclic ketene-N,O/S-acetal intermediates which then react

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::386eed9e0901b083096a37124a8f7907
https://doi.org/10.1016/j.tetlet.2012.03.068

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One pot synthesis of α,α-bis(N-arylamido) lactams via iodide-catalyzed rearrangement of β,β-bis(N-arylamido) cyclic ketene-N,O-acetals

Autor: William P. Henry, Hondamuni I. De Silva, Yingquan Song, Guozhong Ye, Charles U. Pittman

Publikováno v: Tetrahedron Letters. 52:853-858

Five and six-membered cyclic ketene-N,O-acetals, generated in situ from 2,3-dimethyl-2-oxazolinium iodide or 2,3-dimethyl-2-oxazinium iodide and triethylamine, reacted with aryl isocyanates in refluxing THF producing α,α-bis(N-arylamido) lactams vi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c3237296391ca8b2d1bdf6ec4e07a874
https://doi.org/10.1016/j.tetlet.2010.11.148

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ChemInform Abstract: One-Pot Synthesis of α,α-Bis(N-arylamido) Lactams via Iodide-Catalyzed Rearrangement of β,β-Bis(N-arylamido) Cyclic Ketene-N,O-acetals

Autor: Hondamuni I. De Silva, Yingquan Song, William P. Henry, Guozhong Ye, Charles U. Pittman

Publikováno v: ChemInform. 42

In situ generated ketene-N,O-acetals react with aryl isocyanates in refluxing THF to produce β,β-bis(N-arylamido) cyclic ketene-N,O-acetals.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f13175ce3468bba6a1010fc02285892c
https://doi.org/10.1002/chin.201122124

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Ultrasensitive detection of malondialdehyde with surface-enhanced Raman spectroscopy

Autor: Svein Saebo, Charles U. Pittman, Karthikeshwar Vangala, Hondamuni I. De Silva, Andrzej Sygula, Rukshani Haputhanthri, Dongmao Zhang, Siyam M. Ansar

Publikováno v: Analytical and bioanalytical chemistry. 398(7-8)

Malondialdehyde (MDA) is a biomarker of lipid peroxidation that has been widely associated with food rancidity as well as many human diseases. Most current MDA detection methods involve MDA reaction with thiobarbituric acid (TBA), followed by UV–vi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a745a6b453e762ff645c6d9de073c78
https://pubmed.ncbi.nlm.nih.gov/20924567

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